Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages. [PDF]
Established cell lines are widely used in research, however an appealing question is the comparability of the cells between various laboratories, their characteristics and stability in time.
Bartłomiej Taciak +7 more
doaj +2 more sources
Biological effects of N-acetylcysteine, calcium hydroxide, chlorhexidine and their combinations as intracanal medications: cytotoxicity, genotoxicity and cytokine modulation [PDF]
Objective This study aimed to evaluate whether the combination of N-acetylcysteine (NAC), a compound with antimicrobial, antioxidant, and immunomodulatory properties, with conventional intracanal medications calcium hydroxide [Ca(OH)₂] and chlorhexidine (
Ana Caroline Freitas da Silva +8 more
doaj +2 more sources
Metformin Improves Burn Wound Healing by Modulating Microenvironmental Fibroblasts and Macrophages
Metformin, a biguanide, exerts different functions through various signaling pathways. In order to investigate the function and mechanism of metformin in burn wounds, we established burn rat models, subcutaneously injected metformin to treat the wounds ...
Liangliang Shi +9 more
doaj +1 more source
Chemoattractant signaling between tumor cells and macrophages regulates cancer cell migration, metastasis and neovascularization. [PDF]
Tumor-associated macrophages are known to influence cancer progression by modulation of immune function, angiogenesis, and cell metastasis, however, little is known about the chemokine signaling networks that regulate this process.
Chad E Green +7 more
doaj +1 more source
Anti-inflammatory Effects of Complex Extract including Eucommia ulmoides in LPS-induced RAW 264.7 Cells [PDF]
Background The purpose of this study was to investigate the anti-inflammatory response of lipopolysaccharide (LPS) activated macrophages (RAW 264.7 murine cell line) to JCE003 which is an extract including Eucommia ulmoides, Juglans regia ...
Hwa Yeon Ryu +3 more
doaj +1 more source
Clostridium difficile spore-macrophage interactions: spore survival. [PDF]
BACKGROUND: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C.
Daniel Paredes-Sabja +4 more
doaj +1 more source
Platycodin D-Induced Immunotoxicity in RAW 264.7 Macrophages via Oxidative Stress-Mediated Apoptosis
Platycodin D (PD) is a naturally occurring, biologically active triterpenoid saponin isolated from a medicinal food homology plant called Platycodon grandiflorus (Jacq.) A. DC. It is involved in the processing of various biological activities.
Xinying Du +5 more
doaj +1 more source
Potential immune-modulatory effects of wheat phytase on the performance of a mouse macrophage cell line, Raw 264.7, exposed to long-chain inorganic polyphosphate [PDF]
Objective This experiment was conducted to find out the immunological effects of wheat phytase when long-chain inorganic polyphosphate (polyP) treated with wheat phytase was added to a macrophage cell line, Raw 264.7, when compared to intact long-chain ...
Jeongmin An, Jaiesoon Cho
doaj +1 more source
Cytotoxicity and anti-inflammatory activity of ethanol extract of Artocarpus altilis (Parkinson ex F.A.Zorn) Fosberg leaf in lipopolysaccharide-stimulated RAW 264.7 cells [PDF]
Context: The flavonoid and phenolic compounds found in Artocarpus altilis have made their popularity. This plant has been used as a traditional medicine in Indonesia for various diseases. Aims: To evaluate the toxic concentration of the A.
Fitrya +3 more
doaj +1 more source
In this study, we isolated sargachromenol (SC) from Sargassum horneri and evaluated its anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages.
Eui-Jeong Han +11 more
doaj +1 more source

