Results 141 to 150 of about 5,986,284 (284)

Effects of continuous and released compressive force on osteoclastogenesis in vitro

Journal of Oral Biology and Craniofacial Research
Objective: Compressive force has been found to be catabolic to alveolar bone during orthodontic tooth movement. This study quantified the fusion of mononuclear RAW 264.7 cells (a murine osteoclastic-like cell line) into multinucleated osteoclasts under a
Boontida Changkhaokham, Sumit Suamphan, Suwanna Jitpukdeebodintra, Chidchanok Leethanakul   +3 more
doaj   +1 more source

Lithium‐Doped Hydroxyapatite Nanowires Rejuvenate Senescent Macrophages Via the Lysosome‐Dependent Ferroptosis Axis to Promote Aged Bone Regeneration

Advanced Science, EarlyView.
Li‐nHAP+GelMA promotes mandibular bone regeneration in aged mice by remodeling the senescent immune microenvironment. Local delivery of Li‐nHAP restores lysosomal homeostasis in senescent macrophages, reduces intracellular labile Fe2+ accumulation, ROS production, and lipid peroxidation, thereby suppressing macrophage ferroptosis and senescence ...
Baixi Chen, Ziduan Ding, Ruomei Li, Cheng Zhu, Zhiyu Zhu, Zitong Yang, Luyao Qu, Jin Hao, Lunguo Xia, Bing Fang, Lu Liu   +10 more
wiley   +1 more source

Biomimetic Nanoplatform for Fibrosis Remodeling and Anti‐PD‐1 Potentiation via Cu+/Ca2+ Ion Dysregulation and TGF‐β Inhibition in PDAC

Advanced Science, EarlyView.
A biomimetic nanoplatform (RPm@CC‐LY) remodels fibrotic stroma via sustained TGF‐β inhibition, triggers oxidative stress and apoptosis through Cu+‐mediated Fenton chemistry and Ca2+ overload, and reprograms macrophages and dendritic cells to boost CD8+ T cell infiltration.
Jianmei Li, Qinlong Wen, Jie Dai, Li Yang, Feng Xiong, Zhigong Wei, Xingchen Peng   +6 more
wiley   +1 more source

Phase‐Programmed Microneedles Enable Sequential Hydrogen and Quercetin Release for Scar‐Reduced Regeneration of Burn Wounds

Advanced Science, EarlyView.
A phase‐programmed microneedle patch, comprising a poly (lactic‐co‐glycolic acid) (PLGA) shell and a sulfobutylether‐β‐cyclodextrin (SBECD) core, is designed for sequential hydrogen and quercetin release for scar‐reduced regeneration of burn wounds. ABSTRACT Burn wounds complicated by bacterial infection and fibrotic scarring remain a major clinical ...
Yongnian Zeng, Zhigang Chu, Huiyuan Yang, Wen Zhang, Peng Jiang, Jiapeng Lei, Siyu Zhang, Qiongfang Ruan, Shuhua Liu, Wei Li   +9 more
wiley   +1 more source

Biological processes and corresponding genes regulated by PGPC in RAW 264.7 macrophages.

, 2014
Biological processes and corresponding genes regulated by PGPC in RAW 264.7 macrophages.
Juliane Gertrude Bogner-Strauß (647808), Daniel Koller (647807), Hubert Hackl (15768), Albin Hermetter (440005)   +3 more
core   +1 more source

pH‐Responsive Ultrasmall Iron Oxide Nanoassemblies for Activatable T2/T1 Magnetic Resonance Imaging

Advanced NanoBiomed Research, EarlyView.
This research reports a pH‐responsive ultrasmall iron oxide nanoparticle (USIONs)/polymer nanoassemblies for activatable magnetic resonance imaging. Amphiphilic diphosphonic acid block copolymers compactly encapsulate USIONs to generate T2‐weighted contrast at physiological pH, while acidic conditions trigger disassembly, activating T1‐weighted ...
Xumin Huang, Liwei Liu, Jiayuan Zhu, Xinghao Hu, Changkui Fu, Yao Wang, Lining Arnold Ju, Thomas P. Davis, Andriansjah Rukmana, Shaohua Ma, Zheng Zhang, Ruirui Qiao   +11 more
wiley   +1 more source

Genes activating cxcl2-pLuc expression in Raw 264.7 cells.

, 2012
Genes activating cxcl2-pLuc expression in Raw 264.7 cells.
David H. Wyllie (145641), Endre Kiss-Toth (147619), Migena Bregu (147614), Xu Yaobo (147606), Karen Holland (147599), Adrian V. S. Hill (40512), Karen C. Søgaard (147591)   +6 more
core   +1 more source

Atheroprotective effect of novel peptides from Porphyridium purpureum in RAW 264.7 macrophage cell line and its molecular docking study.

, 2019
Objective To explore the atherogenic foam cell prevention efficiency of two dipeptides purified from Porphyridium purpureum on RAW 264.7 cell line and to study its molecular interaction through molecular docking. Result P. purpureum consists of 29.9%
Shilpa, T. S., Nandini, P. Shetty, Kavitha, M. D., Aditya Rao, S. J., Mallikarjun Gouda, K. G., Sarada, R.   +5 more
core   +1 more source

A nanoplatform that induces dual‐amino acid deprivation to reverse tumor immunosuppression and enhance metabolic immunotherapy

BMEMat, EarlyView.
ZIF‐8‐based nanoparticles co‐delivering CB‐839 (glutaminase inhibitor) and 1‐MT (IDO1 inhibitor), dual‐targeting glutamine/tryptophan metabolism to induce immunogenic cell death, activate STING, block kynurenine production, reverse immunosuppression, and enhance cancer immunotherapy to suppress primary/distant tumors.
Wenli Ning, Yunhan Sun, Mingyang Li, Shilu Liu, Fangjie Yi, Hongfei Wang, Ruibing Bai, Dongdong Liu, Fen Zhao, Guiqiang Zhang, Xiao Fu   +10 more
wiley   +1 more source

Cytotoxic activity (IC₅₀ value) of S. nigrum polysaccharide fractions against RAW 264.7 cell line and killing percentage at maximum concentration.

, 2014
**Positive control. Values are expressed as mean ± standard deviation (n = 3).
Amirah Ismail (641691), Adawiyah Suriza Shuib (641692), Nurhayati Zainal Abidin (325499), Faizan Naeem Razali (641690)   +3 more
core   +1 more source