Results 41 to 50 of about 726,846 (313)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Rice Husk Hydrolytic Lignin Transformation in Carbonization Process

Molecules, 2019
Lignin processing products have an extensive using range. Because products properties depend on lignin precursor quality it was interesting to study lignin isolated from rice husk being a large tonnage waste of rice production and its structural ...
Svetlana Yefremova, Abdurassul Zharmenov, Yurij Sukharnikov, Lara Bunchuk, Askhat Kablanbekov, Kuanish Anarbekov, Tetiana Kulik, Alina Nikolaichuk, Borys Palianytsia   +8 more
doaj   +1 more source

raw materials scoreboard

, 2016
The raw materials scoreboard is an initiative of the European Innovation Partnership (EIP) on Raw Materials. Its purpose is to provide quantitative data on the EIP's general objectives and on the raw materials policy context. It presents relevant and reliable information that can be used in policymaking in a variety of areas.
VIDAL LEGAZ Beatriz, BLENGINI Giovanni, MATHIEUX Fabrice, LATUNUSSA Cynthia, MANCINI Lucia, NITA Viorel, HAMOR Tamas, ARDENTE Fulvio, NUSS Philip, TORRES DE MATOS Cristina, WITTMER Dominic, TALENS PEIRO Laura, GARBOSSA Elisa, PAVEL Claudiu, ALVES DIAS Patricia, BLAGOEVA Darina, BOBBA Silvia, HUISMAN Jacob, EYNARD, UMBERTO, DI PERSIO Franco, DOS SANTOS GERVASIO Helena, CIUPAGEA Constantin, PENNINGTON David   +22 more
openaire   +4 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Study on Occurrence Status Characteristics of Trace Elements in Imported Indonesia Coals of Shanghai Port Using Inductively Coupled Plasma-Mass Spectrometry and Atomic Fluorescence Spectrometry

Yankuang ceshi, 2015
Indonesia is the largest coal importer of China. In this paper, the concentrations of 12 elements in 31 imported Indonesia coal samples were determined using inductively coupled plasma mass spectrometry (ICP-MS), atomic fluorescence spectrometry (AFS ...
LIU Shu, SHEN Jie, ZHOU Hai-min, ZHU Xiu-fen, ZHU Zhi-xiu, LI Chen, LAN Chao   +6 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Effect of B4C particle size on the mechanical properties of B4C reinforced aluminum matrix layered composite

Science and Engineering of Composite Materials, 2019
Reinforcement particle size is very important for the performance of metal ceramic composites. This work studied the influence of B4C particle size on the mechanical properties of Al matrix layered composites.
Xu Guangye, Yu Yingshui, Zhang Yubo, Li Tingju, Wang Tongmin   +4 more
doaj   +1 more source

Based on metabolomics, the optimum wind speed process parameters of flue-cured tobacco in heat pump bulk curing barn were explored

Scientific Reports, 2023
To explore the influence of wind speed on the quality of tobacco in this study, we employed a heat pump-powered intensive curing barn and a three-stage curing process.
Cheng Lin Sun, Hui Lin Zhang, Dong Bo Zhou, Zhi Jun Cheng, You Xie, Zhong Wen Rang, Lin Jian Dai   +6 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source