Results 51 to 60 of about 1,000,893 (259)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Aflatoxin B1 adsorption by the natural aluminosilicates - concentrate of montmorillonite and zeolite [PDF]

open access: yesHemijska Industrija, 2016
Aflatoxin B1 adsorption by the concentrate of bentonite clay - montmorillonite and the natural zeolite - clinoptilolite and was investigated at the initial toxin concentration 4 ppm, with different amonunts of solid phase in suspension (10, 5, 2
Marković Marija A.   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Effect of La2O3 on the structure and the properties of strontium borate glasses [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2016
The selected lanthanum-strontium-borate glasses were prepared by a conventional melt-quenching technique. The compositions of the investigated glasses were chosen to be: 5.7, 9.5, 14.3, 19.1 mol % for La2O3, 22.9, 19.1, 14.3, 9.5 for mol % SrO ...
Smiljanić Sonja V.   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Phase equilibria study and characterization of the alloys in the BiCu0.5Ni0.5 section of the Bi-Cu-Ni system [PDF]

open access: yesTehnika, 2017
The Bi-Cu-Ni system is a very significant, because its alloys belong to the group of potential Cu-Ni-based advanced lead-free solder materials for high temperature application.
Marković Branislav   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

The valorization impact and methods for treatment of non ferrous secondary raw materials [PDF]

open access: yesTehnika, 2017
Production of non ferrous metals from secondary raw materials is far less costly than its production from primary raw materials, due to lower energy consumption.
Sokić Miroslav   +5 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Treatment of flue gas and coal to reduce air pollution-overview [PDF]

open access: yesPodzemni Radovi
This paper presents the procedures that can be used to reduce air pollution that originates from the burning of fossil fuels. Research has shown that burning coal is the largest source of emissions of greenhouse gases such as carbon dioxide, sulfur ...
Mihajlović Slavica R.   +3 more
doaj   +1 more source

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