Results 31 to 40 of about 9,004,370 (343)
Italian Journal of Medicine, 2013 Introduction: The term scleroderma derives from the Greek words skleros, which means hard, and derma, which means skin. It refers to an acquired systemic inflammatory disease of the connective tissue –also known as systemic sclerosis (SSc)– characterized
Domenico Galasso +2 more
doaj +1 more source
Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance [PDF]
, 2015 Seliciclib (R-Roscovitine) was identified as an inhibitor of CDKs and has undergone drug development and clinical testing as an anticancer agent. In this review, the authors describe the discovery of Seliciclib and give a brief summary of the biology of ...
Cavicchi, Laura +4 more
core +4 more sources
The impact of Raynaud’s phenomenon on work ability – a longitudinal study
Journal of Occupational Medicine and Toxicology, 2022 Objective To determine if having Raynaud’s phenomenon (RP) affects the work ability, job retainment, or occurrence of sick leave. Methods Surveys on the working-age general population of northern Sweden were conducted in 2015 and 2021, gathering data on ...
Albin Stjernbrandt, Jens Wahlström
doaj +1 more source
Arthritis care & research, 2019 Assessment of Raynaud's phenomenon (RP) in systemic sclerosis (SSc) is reliant on self‐report. The Raynaud's Condition Score (RCS) diary assumes discrete episodic RP attacks, although not all SSc patients identify with this paradigm.
J. Pauling +3 more
semanticscholar +1 more source
Case Reports in Rheumatology, 2023 Antisynthetase syndrome is a rare autoimmune disease within the subset of idiopathic inflammatory myopathies. The diagnostic criteria include the presence of an aminoacyl-tRNA synthetase antibody, and typical clinical findings, including myositis ...
Anusha Vege, Jesse Beery, Areeba Kara
doaj +1 more source
Revista Brasileira de Reumatologia, 2012 OBJETIVO: Avaliar a ação do medicamento inibidor do receptor de leucotrieno CysLT1 (montelucaste) nas alterações vasculares das mãos em pacientes com fenômeno de Raynaud.
Mario Newton Leitão de Azevedo +6 more
doaj +1 more source
Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]
, 2018 ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core +2 more sources