Results 51 to 60 of about 6,826 (151)

Visual Hypersensitivity as a Transdiagnostic Marker of Surgical Pain Response in Arthritis and Chronic Pain Syndromes

open access: yesArthritis &Rheumatology, Volume 78, Issue 6, Page 1339-1349, June 2026.
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller   +15 more
wiley   +1 more source

Acute Finger Ischemia Evaluated With Point‐Of‐Care‐Ultrasound and Diagnosed With Concurrent Polycythemia Vera, Antiphospholipid Syndrome, and Tobacco Use

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
We present a case of digital ischemia investigated and localized using point‐of‐care ultrasound (POCUS), in a patient that was subsrquently diagnosed with antiphospholipid syndrome and polycythemia vera concurrently, in the setting of active tobacco use. ABSTRACT In patients with undifferentiated extremity ischemia, point‐of‐care ultrasound (POCUS) can
Tristan Burgess   +2 more
wiley   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

open access: yesiNew Medicine, Volume 2, Issue 2, June 2026.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong   +5 more
wiley   +1 more source

Cold Agglutinin Disease–Like Genetic Signatures in Lymphoplasmacytic Lymphoma–Like Cases Challenge the WHO Fifth Edition Classification

open access: yeseJHaem, Volume 7, Issue 3, June 2026.
ABSTRACT Background The fifth edition of the World Health Organization (WHO) classification defines cold agglutinin disease (CAD) as a clonal B‐cell lymphoproliferative disorder occurring in the absence of overt lymphoma, whereas cases associated with lymphoma are classified as cold agglutinin syndrome (CAS).
Yuki Sato   +7 more
wiley   +1 more source

Association Between Pruritus and Healthcare Utilization and Costs Among Individuals With Primary Biliary Cholangitis

open access: yesLiver International Communications, Volume 7, Issue 2, June 2026.
ABSTRACT Background and Aims Pruritus is a debilitating, under‐prioritized symptom of primary biliary cholangitis (PBC). This study assessed its impact on healthcare resource utilization (HCRU) and costs in the US. Methods A retrospective cohort study of individuals with PBC was conducted using Komodo's claims and laboratory data between September 1 ...
Robert G. Gish   +8 more
wiley   +1 more source

Hexopal in Raynaud's Disease

open access: yesJournal of International Medical Research, 1979
Twenty female patients with primary Raynaud's phenomenon were included in a 9-month open assessment of Hexopal® tablets. Measurements of digital artery blood velocity rates by transcutaneous Doppler techniques, digital artery pressure by micromanometry, and hand blood flow by venous occlusion plethysmography were undertaken at regular intervals ...
openaire   +2 more sources

The Effect of an Autoimmune Protocol (AIP) Diet in Adults With Rheumatoid Arthritis: A Single Arm Crossover Pilot Feasibility Study

open access: yesMusculoskeletal Care, Volume 24, Issue 2, June 2026.
ABSTRACT Background Individuals with rheumatoid arthritis (RA) often ask whether dietary changes or food exclusions can reduce symptoms. The Autoimmune Protocol (AIP) diet, an elimination‐based approach, is popular on social media, with anecdotal reports of benefit, but lacks clinical evaluation in RA.
Julianne J. McNeill   +3 more
wiley   +1 more source

Quantitative T2* Magnetic Resonance Imaging for Iron Detection in Soft Tissue of the Fingers

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
T2* MRI was evaluated for detecting iron in soft tissues of the fingers. After visual inspection of dual‐colored maps, multiple regions of interest were placed in the soft tissues at areas that indicated increased susceptibility. Lower T2* values, indicative of iron deposition, were detected in patients with microvasculopathy (right panel) but not in ...
Artemis Galani   +6 more
wiley   +1 more source

CMR‐derived left ventricular pressure‐volume loops enhance individualized assessment of disease severity and prognosis in pulmonary arterial hypertension in adults

open access: yesPhysiological Reports, Volume 14, Issue 11, June 2026.
Abstract In pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance (PVR) causes right ventricular pressure overload and left ventricular (LV) underfilling. We investigated LV mechanics and their prognostic value in PAH using cardiovascular magnetic resonance (CMR)‐derived LV pressure‐volume (PV) loops.
Alessandro Castiglione   +5 more
wiley   +1 more source

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