Results 51 to 60 of about 4,865,556 (281)

Raynaud's Disease in Children [PDF]

open access: yesCirculation, 1967
Six children with primary Raynaud's disease have been studied with plethysmography and multiple-site skin-temperature readings. All six were free of systemic disease. Each demonstrated the characteristic sequence of pallor, cyanosis, and rubor when subjected to generalized cold, but application of local cold produced only modest reduction in skin ...
W G, Guntheroth   +3 more
openaire   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Pesticide-induced systemic scleroderma: a case report

open access: yesКлиническая практика
BACKGROUND: Systemic sclerosis, or systemic scleroderma, is a rare autoimmune connective tissue disease. The presented clinical case highlights that taking an occupational history is essential in patients with suspected systemic connective tissue ...
Olga A. Georginova   +7 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich   +35 more
wiley   +1 more source

Fenómeno de Raynaud. Revisión [PDF]

open access: yes, 2014
Raynaud\u27s phenomenon is an exaggerated vascular response to cold or stress manifested by skin colour changes at several locations, having three characteristic phases: pallor (white), cyanosis (blue) and rubor (red).
Jaramillo-Arroyave, Daniel   +1 more
core   +1 more source

Premature stroke and cardiovascular risk in primary Sjögren's syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2022
IntroductionPrimary Sjögren's syndrome (pSS) is associated with an increased prevalence of traditional risk factors and cardiovascular diseases (CVDs). The study aimed to identify specific risk factors for CVD in pSS patients.MethodsPSS patients with and
Clara L. Zippel   +10 more
doaj   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa   +3 more
wiley   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo   +9 more
wiley   +1 more source

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