Results 51 to 60 of about 6,826 (151)
Objective Nociplastic pain is pain primarily driven by the central nervous system and, unlike nociceptive pain conditions, is thought to be refractory to peripherally directed therapies. Nociplastic pain is also associated with hypersensitivity to painful and other sensory stimuli (such as visual stimuli). Nonpainful sensory measures have not been well
Noah Waller +15 more
wiley +1 more source
We present a case of digital ischemia investigated and localized using point‐of‐care ultrasound (POCUS), in a patient that was subsrquently diagnosed with antiphospholipid syndrome and polycythemia vera concurrently, in the setting of active tobacco use. ABSTRACT In patients with undifferentiated extremity ischemia, point‐of‐care ultrasound (POCUS) can
Tristan Burgess +2 more
wiley +1 more source
The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong +5 more
wiley +1 more source
ABSTRACT Background The fifth edition of the World Health Organization (WHO) classification defines cold agglutinin disease (CAD) as a clonal B‐cell lymphoproliferative disorder occurring in the absence of overt lymphoma, whereas cases associated with lymphoma are classified as cold agglutinin syndrome (CAS).
Yuki Sato +7 more
wiley +1 more source
ABSTRACT Background and Aims Pruritus is a debilitating, under‐prioritized symptom of primary biliary cholangitis (PBC). This study assessed its impact on healthcare resource utilization (HCRU) and costs in the US. Methods A retrospective cohort study of individuals with PBC was conducted using Komodo's claims and laboratory data between September 1 ...
Robert G. Gish +8 more
wiley +1 more source
Twenty female patients with primary Raynaud's phenomenon were included in a 9-month open assessment of Hexopal® tablets. Measurements of digital artery blood velocity rates by transcutaneous Doppler techniques, digital artery pressure by micromanometry, and hand blood flow by venous occlusion plethysmography were undertaken at regular intervals ...
openaire +2 more sources
ABSTRACT Background Individuals with rheumatoid arthritis (RA) often ask whether dietary changes or food exclusions can reduce symptoms. The Autoimmune Protocol (AIP) diet, an elimination‐based approach, is popular on social media, with anecdotal reports of benefit, but lacks clinical evaluation in RA.
Julianne J. McNeill +3 more
wiley +1 more source
Quantitative T2* Magnetic Resonance Imaging for Iron Detection in Soft Tissue of the Fingers
T2* MRI was evaluated for detecting iron in soft tissues of the fingers. After visual inspection of dual‐colored maps, multiple regions of interest were placed in the soft tissues at areas that indicated increased susceptibility. Lower T2* values, indicative of iron deposition, were detected in patients with microvasculopathy (right panel) but not in ...
Artemis Galani +6 more
wiley +1 more source
Abstract In pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance (PVR) causes right ventricular pressure overload and left ventricular (LV) underfilling. We investigated LV mechanics and their prognostic value in PAH using cardiovascular magnetic resonance (CMR)‐derived LV pressure‐volume (PV) loops.
Alessandro Castiglione +5 more
wiley +1 more source

