Results 61 to 70 of about 6,997 (197)

Association of Elevated Platelets and C‐Reactive Protein With Severe Disease and Poor Survival in Systemic Sclerosis

open access: yesArthritis Care &Research, EarlyView.
Objective Elevated C‐reactive protein (CRP) levels in systemic sclerosis (SSc) have been linked with severe disease and worse survival, but the role of platelet levels remains unclear. This study examined whether elevated platelet levels, CRP levels, or both are associated with disease severity, progression, and survival in SSc.
Brian S. Lee   +4 more
wiley   +1 more source

SYPHILIS AND RAYNAUD'S DISEASE [PDF]

open access: yesArchives of Internal Medicine, 1915
The coincidence of syphilis and Raynaud's disease has occasionally been observed. A few cases have been reported in which the diagnosis of Raynaud's disease was unwarranted, and in which we were dealing with a pure specific obliterative endarteritis ; in other cases in which the diagnoses are beyond question, the interdependence is very frail and ...
openaire   +2 more sources

Long Noncoding RNA H19 Mediates STAT3‐Dependent Activation of Keratinocytes and Fibroblasts in Systemic Sclerosis Skin

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dermal systemic sclerosis (SSc) fibroblasts and their exosomes can activate keratinocytes in SSc, with long noncoding RNA (lncRNA) H19 highlighted as the most up‐regulated RNA in their cargo compared with healthy controls (HCs). The role of H19 in SSc pathogenesis has never been investigated.
Begoña Caballero‐Ruiz   +3 more
wiley   +1 more source

The evaluation of the Myxovirus Resistance 1 protein in serum and saliva to monitor disease activation in primary Sjögren’s syndrome

open access: yesClinics
OBJECTIVE: Primary Sjögren’s syndrome (pSjS) is a chronic autoimmune disease that causes dry eye and mouth. No laboratory parameters to monitor the activation of this disease have been identified.
Yasemin Gul Aydemir, Ahmet Kocakusak
doaj   +1 more source

Expert Perspectives: Defining and Managing Progressive Pulmonary Fibrosis in Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Systemic sclerosis–associated interstitial lung disease (SSc‐ILD) is one of the leading causes of morbidity and mortality in SSc, affecting up to three‐quarters of patients. The disease course is highly heterogeneous, ranging from indolent, nonprogressive forms to rapidly progressive pulmonary fibrosis (PPF).
Devis Benfaremo   +7 more
wiley   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

open access: yesArthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz   +13 more
wiley   +1 more source

Peripheral Blood DNA Methylation Changes Precede Lymphoma Diagnosis in Primary Sjögren's Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Primary Sjögren's disease (SjD) is a systemic autoimmune disease associated with an increased risk of lymphoma. The molecular mechanisms underlying lymphomagenesis remain poorly understood, and sensitive biomarkers for early identification of patients at high risk of developing lymphoma are lacking.
Hanna Lidberg   +2 more
wiley   +1 more source

Síndrome de CREST. Presentación de un caso CREST syndrome. Presentation of a case

open access: yesRevista Médica Electrónica, 2010
Como esclerodermia, se designa un grupo de enfermedades y síndromes que tienen como característica común la induración y el engrosamiento cutáneos.
Yanet Acosta Piedra   +4 more
doaj  

Autoantibody Profile of Egyptian Juvenile Systemic Lupus Erythematosus Patients and Its Association with Clinical Characteristics and Disease Activity

open access: yesOpen Access Rheumatology: Research and Reviews, 2021
Mohammed Abd El Monem Teama,1 Marwa Adham El-Mohamdy,2 Fatma Abdellah Abdullah Mahmoud,2 Fatma Mohammed Badr1 1Internal Medicine Department, Division of Rheumatology and Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt; 2Clinical ...
Abd El Monem Teama M   +3 more
doaj  

Fetal growth trajectories and neonatal outcomes: A French population‐based study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study assesses whether fetal growth trajectories are associated with neonatal outcomes. Methods The study population included 8537 singleton liveborn infants from the 2021 French National Perinatal Survey. Fetal growth trajectories were assessed between second and third trimester routine ultrasounds and between the third ...
Pierre Gibert   +22 more
wiley   +1 more source

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