Results 21 to 30 of about 350 (140)
Synthesis of chiral carbosilane dendrimers with L-cysteine and N-acetyl-L-cysteine on their surface and their application as chiral selectors for enantiomer separation by capillary electrophoresis [PDF]
, 2017 The synthesis of chiral carbosilane dendrimers functionalized with cysteine and Nacetylcysteine groups is presented in this work. These dendrimers were obtained through thiol-ene addition reactions and their application as chiral selectors in Capillary ...
Quintana Sánchez, Sara +11 more
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RAZOXANE FOR CROHN'S COLITIS AND NON‐SPECIFIC PROCTITIS
International Journal of Clinical Practice, 1992 SUMMARYOral razoxane 125 mg daily brought active Crohn's disease into remission when used alone and mainly on an out‐patient basis in all nine patients studied. Remissions took several months to achieve, but no relapses have occurred on treatment and no surgery has been necessary in any of the patients.In the two patients with active non‐specific ...
R D, Kingston, K, Hellman
openaire +2 more sources
The metabolism of razoxane and dexrazoxane in the Sprague-Dawley rat
, 1998 The objectives of this project were to use a rat model to study the stereoselective metabolism of razoxane and the metabolism of dexrazoxane to its intermediate hydrolysis products. A solid phase method for extraction of razoxane from plasma and a chiral
Aoyama, Ronald G.
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, 1991 The effects of conventional vs protected housing, and those caused by the periodic application of a psychological stressor (rotational stress, spatial disorientation) on mice kept in a protected housing, with spontaneous tumor metastasis have been ...
RAPOZZI, Valentina +4 more
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Inhibition of experimental colorectal cancer by razoxane (ICRF-159)
Journal of British Surgery, 1984 Abstract Large bowel cancer induced in rats by dimethylhydrazine (DMH) closely resembles human disease both histologically and clinically. In this study it has been used to assess the antimitotic drug razoxane (ICRF-159). Dimethylhydrazine induced benign colorectal tumours after 20 weeks and adenocarcinomas from 30 weeks.
J M, Gilbert +3 more
openaire +2 more sources
, 1984 Thirty-one patients with advanced squamous cell carcinoma of the cervix were entered onto this phase II study evaluating the efficacy of ICRF-159 (razoxane).
Hatch, K +5 more
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Iron binding by certain anticancer pharmaceuticals
, 1992 The importance of Fe(III)-chelation in the biological activity of the anticancer pharmaceutical Razoxane has been investigated. Since Razoxane is known to be hydrolysed in vivo to form a potential complexing agent, the observed biological effect o ...
McLay, Paula
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Successful management of primary sarcoma of the breast with complete pathological response: a case report. [PDF]
J Surg Case Rep, 2023 Arafat H +3 more
europepmc +1 more source
, 1986 Rapidly growing normal human neonatal prokeratinocytes (HPK) cultured in serum-free medium can be induced to undergo either reversible or irreversible growth arrest at distinct cell cycle states. Reversible G1 arrest was induced by culture of low-density
Scott, Robert E +2 more
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Dexrazoxane: A New Cardioprotective Agent
, 1998 Objective: To review the literature discussing the use of dexrazoxane (e.g., Zinecard, ICRF-187) to prevent doxorubicin-induced cardiotoxicity. Data Sources: Pertinent English-language reports of studies in humans were retrieved from a MEDLINE search ...
Beverly D Abbott, Cindy M Ippoliti
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