Results 51 to 60 of about 49,770 (119)

Targeted Therapies in the Most Common Advanced Solid Tumors, Drug Resistance, and Counteracting Progressive Micrometastatic Disease: The Next Frontier of Research

MedComm, Volume 6, Issue 10, October 2025.
In TME, undetectable DCCs (panel A) join with a low tumor burden along with low immune suppression, that favor successful immune manipulation through immune suppression inhibiting immune‐therapy. This moves the immune balance toward the immune response and likely makes more stable the dormant state of DCCs in the unstable metastatic niche and/or allows
Andrea Nicolini, Paola Ferrari, Roberto Silvestri, Dario A. Bini   +3 more
wiley   +1 more source

Interleukin-2 receptor β chain as a possible target for low doses of mafosfamide

Mediators of Inflammation, 1995
The 7-day cytotoxic lymphocytes (CTL) induced in mixed lymphocyte culture express only the chain of the interleukin-2 receptor (IL-2R). In the present study this fact has been confirmed in a murine semi-allogeneic system.
A. Pukhalsky, A. Toptygina, S. Khaidukov
doaj   +1 more source

A Comprehensive Correlation of Clinicopathologic Prognostic Factors in Malignant Adult Renal Tumors: A Single Institutional Study [PDF]

Türk Patoloji Dergisi
Objective: To study the clinicopathologic prognostic parameters of malignant adult renal tumors as these have poor over-all survival (OS) and show frequent metastasis. Material and Methods: This was a retrospective analysis of the clinical and pathologic
Sobiya M AYESHA, Swetha SIVAKUMAR, Rahul DEVRAJ, Rajsekhar SHANTAPPA, Ranganath RATNAGIRI, Meher Lakshmi KONATAM, Shantveer G UPPIN, Tara Roshni PAUL, Megha S UPPIN   +8 more
doaj   +1 more source

Microscopic precursor lesions of uterine lymphangioleiomyomatosis associated with incidental nodal lymphangioleiomyomatosis: A case report and discussion of pathogenesis

Human Pathology: Case Reports, 2020
A 47 yo woman underwent resection of an endometrial adenocarcinoma with pelvic lymph node biopsies. She was found to have incidental nodal lymphangioleiomyomatosis (LAM).
Charles M. Lombard
doaj   +1 more source

Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Its Implications for Prophylactic and Therapeutic Pharmaceuticals

MedComm, Volume 6, Issue 10, October 2025.
Respiratory syncytial virus (RSV) causes substantial global morbidity, particularly in infants and elderly populations. This review summarizes key viral pathogenesis mechanisms and highlights recent advances in both prophylactic (vaccines, antibodies) and therapeutic (antiviral agents) strategies against RSV.
Xiaowen Liang, Yue Yin, Yuanlong Lin, Shiman Chen, Qi Qian, Jing Yuan, Liuqing Yang, Yang Yang   +7 more
wiley   +1 more source

Suppressive Activity of a Macrolide Antibiotic, Roxithromycin, on Pro-Inflammatory Cytokine Production in Vitro and in Vivo

Mediators of Inflammation, 1999
This study was designed to examine the influence of a macrolide antibiotic, roxithromycin (RXM), on the production of pro-inflammatory cytokines, interleukin (IL)-1β and tumor necrosis factor (TNF)-α.
H. Suzaki, K. Asano, S. Ohki, K. Kanai, T. Mizutani, T. Hisamitsu   +5 more
doaj   +1 more source

Lumps and Bumps on the Abdominal Wall: Role of Fine Needle Aspiration Cytology [PDF]

Türk Patoloji Dergisi
Objective: Abdominal wall masses often pose diagnostic challenges for clinicians due to their nonspecific symptoms. They include a wide spectrum of lesions ranging from inflammatory to tumor-like masses and malignancies.
Anjali ASHTAKAR, Asha SHENOY, Mona AGNIHOTRI, Kanchan KOTHARI   +3 more
doaj   +1 more source

The Isosteroid Alkaloid Imperialine from Bulbs of Fritillaria cirrhosa Mitigates Pulmonary Functional and Structural Impairment and Suppresses Inflammatory Response in a COPD-Like Rat Model

Mediators of Inflammation, 2016
Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the world. Present therapies for COPD have limited effect on reducing the progression of COPD and suppressing the inflammatory response in the lung.
Dongdong Wang, Qingdan Du, Houcong Li, Shu Wang   +3 more
doaj   +1 more source

Under the Microscope: A Case Report of Thoracic SMARCA4-Deficient Undifferentiated Tumor with Review of the Literature [PDF]

Türk Patoloji Dergisi
Objective: SMARCA4-deficient undifferentiated tumor (SMARCA4-UT) is a highly malignant neoplasm with an undifferentiated or rhabdoid phenotype, posing a diagnostic challenge.
Manasi MUNDADA, Khalid ABDUL MANNAN, Divya VASU, Faiq AHMED, Suseela K   +4 more
doaj   +1 more source

A Case of Nasal Glial Heterotopia That Can Be Misdiagnosed as Storiform Patterned Sclerotic Fibroma/Collagenoma [PDF]

Türk Patoloji Dergisi
Objective: Nasal glioma, also known as nasal glial heterotopia, is a rare tumor-like lesion that often affects newborns or infants with no hereditary predisposition.
Fatma GUNDOGDU, Deniz ATES OZDEMIR, Ibrahim VARGEL   +2 more
doaj   +1 more source