Results 31 to 40 of about 53,919 (139)

Bridging the Late Antique Gap in Northwest Arabia: New Archaeological Evidence on the Occupation of Wādī al‐Qurā (al‐ʿUlā [AlUla], Saudi Arabia) Between the Third and Seventh Centuries CE

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT In 2019, the Dadan Archaeological Project (CNRS/RCU/AFALULA) identified a Late Antique village 1 km south of ancient Dadan in the al‐ʿUlā valley (northwest Saudi Arabia). Three excavation seasons at this site (2021–2023) have uncovered a massive building constructed in the late third or early fourth cent.
Jérôme Rohmer, Abdulrahman Alsuhaibani, Charlène Bouchaud, Elora Chambraud, Vladimir Dabrowski, Hatem Djerbi, Fabien Lesguer, Hervé Monchot, Paul Picavet, Louise Purdue, Bertrand Riba, Shadi Shabo   +11 more
wiley   +1 more source

Peculiarities of transient hyperglycemia in ischemic hemispheric stroke in patients with obesity

Patologìâ, 2012
Ischemic strokes in abdominally obese patients have more severe clinical course. We analyzed glycemia indicators during the first day after hemispheric ischemic strokes in patients with different obesity types and with definite cerebral lesion volumes ...
M. Yu. Delva
doaj   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Inhibition of poly(ADP-ribose)polymerase contributes to the reduction of oxidative stress in murine liver under the conditions of experimental endotoxemia

Patologìâ, 2019
The aim of the work is to investigate the effect of the enzyme poly(ADP-ribose)polymerase 1 (PARP-1) inhibitor, 4-hydroxyquinazoline (4-HQN), on the state of the pro- and antioxidant system of murine liver, under the conditions of lipopolysaccharide (LPS)
N. H. Hrushka, S. I. Pavlovych, O. A. Kondratska, N. O. Pilkevych, R. I. Yanchii   +4 more
doaj   +1 more source

Recurrent and novel fusions detected by targeted RNA sequencing as part of the diagnostic workflow of soft tissue and bone tumours

The Journal of Pathology: Clinical Research
The identification of gene fusions has become an integral part of soft tissue and bone tumour diagnosis. We investigated the added value of targeted RNA‐based sequencing (targeted RNA‐seq, Archer FusionPlex) to our current molecular diagnostic workflow ...
Rafael Zago Baltazar, Sofie Claerhout, Sara Vander Borght, Lien Spans, Raphael Sciot, Patrick Schöffski, Daphne Hompes, Friedl Sinnaeve, Hazem Wafa, Marleen Renard, Mari FCM van den Hout, Astrid Vernemmen, Louis Libbrecht, An‐Katrien De Roo, Filomena Mazzeo, Cédric van Marcke, Karen Deraedt, Claire Bourgain, Isabelle Vanden Bempt   +18 more
doaj   +1 more source

Role of cancer‐associated fibroblast‐derived exosomal microRNAs in breast cancer progression: A systematic review

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Yy Abstract Background Cancer‐associated fibroblasts (CAFs) are key components of the breast cancer tumor microenvironment and mediate communication with tumor cells through extracellular vesicles carrying microRNAs (miRNAs). These miRNAs may influence breast cancer progression by regulating oncogenic and tumor‐suppressive pathways.
Matine Hajarian‐Rezazadeh, Fatemeh Fattahi, Mahmood Shekari‐Khaniani, Mehdi Khorrami, Akbar Amirfirouzi   +4 more
wiley   +1 more source

Gastric cancer immune microenvironment score predicts neoadjuvant chemotherapy efficacy and prognosis

The Journal of Pathology: Clinical Research
The efficacy of neoadjuvant chemotherapy (NACT) in patients with advanced gastric cancer (GC) varies greatly. Thus, we aimed to verify the predictive value of tumor‐infiltrating immune cells (TIICs) on the treatment response to NACT and the prognosis of ...
Shaoji Zhao, Yinan Liu, Li Ding, Chaoyue Zhang, Jinning Ye, Kaiyu Sun, Wu Song, Shirong Cai, Yulong He, Jianjun Peng, Jianbo Xu   +10 more
doaj   +1 more source

Features of cerebral hemodynamics and vascular autoregulation in chronic cerebral ischemia

Patologìâ, 2013
Introduction. The problem of cerebrovascular diseases in Ukraine and the world is one of the urgent problems of modern clinical medicine. The most wide-spread such a disease is chronic ischemic attack. These aspects determine the relevance of studying
O.A. Kozyolkin, S.V. Yarkova
doaj   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Peptide BG From Bitter Gourd (Momordica Charantia) Improves Adjuvant-Induced Arthritis by Modulating the Necroptosis/Neutrophil Extracellular Traps/Inflammation Axis and the Gut Microbiota

Mediators of Inflammation
Conclusion: Peptide BG has demonstrated efficacy in ameliorating AIA through its regulation of the necroptosis/NETs/inflammation axis and the gut microbiota. This finding underscores the potential of BG as a promising therapeutic intervention for RA.
Wenyan Han, Yanan Xu, Suyila Qimuge, Changshan Wang, Xiulan Su   +4 more
doaj   +1 more source