Results 31 to 40 of about 177,602 (172)

Spatial Mapping the Dengue and Chikungunya Burden in a Rural Area near Bangalore: a Descriptive Cross-Sectional Study

Journal of Arthropod-Borne Diseases
Background: The burden of dengue and chikungunya diseases across geographical regions of India is poorly quantified more so during Covid19 pandemic and from hospital-based studies.
N R Ramesh masthi, Divya Bharathi G
doaj   +1 more source

Identification and characterization of seven new exon 11-associated splice variants of the rat mu opioid receptor gene, OPRM1

Molecular Pain, 2011
Background The mouse mu opioid receptor (OPRM1) gene undergoes extensive alternative splicing at both the 3'- and 5'-ends of the gene. Previously, several C-terminal variants generated through 3' splicing have been identified in the rat OPRM1 gene.
Pasternak Gavril W, Rossi Grace C, Xu Mingming, Xu Jin, Pan Ying-Xian   +4 more
doaj   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Na_v1.7 expression is increased in painful human dental pulp

Molecular Pain, 2008
Background Animal studies and a few human studies have shown a change in sodium channel (NaCh) expression after inflammatory lesions, and this change is implicated in the generation of pain states. We are using the extracted human tooth as a model system
Levinson S Rock, Perry Griffin M, Luo Songjiang, Henry Michael A   +3 more
doaj   +1 more source

Bridging the Late Antique Gap in Northwest Arabia: New Archaeological Evidence on the Occupation of Wādī al‐Qurā (al‐ʿUlā [AlUla], Saudi Arabia) Between the Third and Seventh Centuries CE

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT In 2019, the Dadan Archaeological Project (CNRS/RCU/AFALULA) identified a Late Antique village 1 km south of ancient Dadan in the al‐ʿUlā valley (northwest Saudi Arabia). Three excavation seasons at this site (2021–2023) have uncovered a massive building constructed in the late third or early fourth cent.
Jérôme Rohmer, Abdulrahman Alsuhaibani, Charlène Bouchaud, Elora Chambraud, Vladimir Dabrowski, Hatem Djerbi, Fabien Lesguer, Hervé Monchot, Paul Picavet, Louise Purdue, Bertrand Riba, Shadi Shabo   +11 more
wiley   +1 more source

RB1 (retinoblastoma) [PDF]

, 1999
Review on RB1 (retinoblastoma), with data on DNA, on the protein encoded, and where the gene is ...
DR Lohmann, Lohmann, DR
core   +1 more source

Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones

Molecular Pain, 2010
Protease-activated receptors (PAR1-4) are activated by proteases released by cell damage or blood clotting, and are known to be involved in promoting pain and hyperalgesia.
Magherini Pier C, Reeh Peter, Hechtfischer Sabine C, Prandini Massimiliano, Kinsey Anna M, Vellani Vittorio, Giacomoni Chiara, McNaughton Peter A   +7 more
doaj   +1 more source

EEPD1 Inhibition Unleashes Antitumor Immunity in Colorectal Cancer by Activating the cGAS‐STING Pathway

Advanced Science, Volume 13, Issue 34, 19 June 2026.
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo, Chong Wu, Xiaobo Li, Caina Ma, Jiamin Huang, Zishuo Chen, Weiling He, Tianyu Tao, Weijing Zhang   +8 more
wiley   +1 more source

Multiple germline sequence variants with potential cancer risk uncovered by exome sequencing in an anatomic lab donor cadaver with multiple cancer lesions

Human Pathology Reports
Ovarian cancer is the leading cause of death among gynecological cancers in most developed countries, with many patients developing chemotherapy resistance leaving them with a 5-year survival rate of 
Jessica Liang, Arben Santo, Peter Samuel, Lin Kang, Katherine Salim, Tiffany Carpenetti, Ramu Anandakrishnan, Pawel Michalak, Harold Garner, Robin T. Varghese   +9 more
doaj   +1 more source

Cortical plasticity as a new endpoint measurement for chronic pain

Molecular Pain, 2011
Animal models of chronic pain are widely used to investigate basic mechanisms of chronic pain and to evaluate potential novel drugs for treating chronic pain.
Zhuo Min
doaj   +1 more source