Results 21 to 30 of about 52,206 (120)
Neurovascular Unit in Chronic Pain
Mediators of Inflammation, 2013 Chronic pain is a debilitating condition with major socioeconomic impact, whose neurobiological basis is still not clear. An involvement of the neurovascular unit (NVU) has been recently proposed.
Beatrice Mihaela Radu +6 more
doaj +1 more source
Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction
Advanced Healthcare Materials, EarlyView.Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang +4 more
wiley +1 more source
npj Precision OncologyOvarian cancer is the most lethal gynecologic malignancy, mainly due to late-stage diagnosis, frequent recurrences, and eventually therapy resistance.
Charlotte Fieuws +9 more
doaj +1 more source
Mediators of Inflammation, 2019 Background and Aims. Overweight is ever more prevalent in the pediatric population, and this cardiometabolic factor can be associated with inflammatory markers, gut microbiota composition, and short-chain fatty acid (SCFA) concentrations. The aim of this
Valter Paulo Neves Miranda +8 more
doaj +1 more source
Advanced Science, EarlyView.In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
Synthetic Phage for Tissue Regeneration
Mediators of Inflammation, 2014 Controlling structural organization and signaling motif display is of great importance to design the functional tissue regenerating materials. Synthetic phage, genetically engineered M13 bacteriophage has been recently introduced as novel tissue ...
So Young Yoo +2 more
doaj +1 more source
Cinical, morphological and functional comparisons in acute period of ischemic hemispheric stroke
Patologìâ, 2013 The aim of the research was the optimization of diagnostic and prognostic approaches in patients in acute period of ischemic supratentorial stroke depending on lateralization of lesion focus on the basis of clinical, computed tomography and computed ...
A. A. Kuznetsov
doaj +1 more source
Advanced Science, EarlyView.Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo +20 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
The Relationship between Torque teno Virus and TLR2 rs5743708 Polymorphism with Breast Cancer
Journal of Medical Microbiology and Infectious Diseases, 2021 Introduction: Breast cancer is one of the most important causes of mortality in women. Various factors are involved in the development of cancer, including viruses. Toll-like receptors (TLRs) have an essential role in the innate immune system.
Majid Komijani +2 more
doaj +1 more source