Results 21 to 30 of about 177,602 (172)

Effects of berberine (BBR) to inhibit the degradation of RB1 mRNA with poly(A) (RB1-pro-RB1) or without poly(A) (RB1-pro-RB1-Δpoly A-).

, 2014
(A) Cartoon of the plasmid models used in this study. Polyadenylation signals were showed in red. (B) Expressions of GFP in cells with transfection of RB1-promoter-RB1-GFP with and without poly(A) plasmids detected using Western blot.
Li-Jun Du (288666), Yu-Shuang Chai (288661), Zhi-Yi Yuan (288662), Feng Du (288665), Fan Lei (288658), Dong-Ming Xing (288664), Jun Hu (5721), Jing-Fei Jiang (288656), Yu-Gang Wang (288657), Xi Lu (288663)   +9 more
core   +1 more source

Pseudosarcomatous myofibroblastic lesion of the urinary bladder: A rare entity posing a diagnostic challenge and therapeutic dilemma

Diagnostic Pathology, 2008
Background Pseudosarcomatous myofibroblastic lesions of the urinary bladder are relatively rare entities of an uncertain pathogenesis and benign indolent nature.
Deliveliotis Charalambos, Chrisofos Michail, Mennonna Maria, Papatsoris Athanasios G, Papathomas Thomas G, Parasi Aikaterini, Lekas Alexandros, Lazaris Andreas C   +7 more
doaj   +1 more source

RB1-Promotormethylierung bei Glioblastomen [PDF]

, 2021
Glioblastome sind astrozytäre Tumore, gehören zu den aggressivsten Tumorerkrankungen des Menschen und sind mit einer infausten Prognose vergesellschaftet.
Breitfelder, Gerrit
core   +1 more source

Knowledge and Practices of Women Regarding Malaria and Its Prevention: A Community-Based Study in an Area under Malaria Elimination Programme in Iran

Journal of Arthropod-Borne Diseases
Background: Indoor residual spraying (IRS) and long-lasting insecticidal nets (LLINs) are two core interventions for control and prevention of malaria infection.
Mehdi Zare, Hassan Vatandoost, Mussa Soleimani-Ahmadi, Alireza Sanei-Dehkordi, Seyed Aghil Jaberhashemi, Shokrollah Mohseni   +5 more
doaj   +1 more source

Chondrosarcoma of the spine: A rare case with unusual presentation

Diagnostic Pathology, 2006
Chondrosarcoma is the third most common primary malignancy of bone, affecting primarily the pelvic and shoulder girdles and being extremely rare in the spine.
Charalabopoulos Konstantinos, Doukas Michael, Michos Evangelos, Voulgaris Spyridon, Panelos John, Batistatou Anna   +5 more
doaj   +1 more source

Species Composition and Spatial Distribution of Medically Important Scorpions in the Northern Part of Kerman Province, Iran

Journal of Arthropod-Borne Diseases
Background: Kerman Province is one of the endemic foci of scorpionism in southeastern Iran. Totally 17 species are reported for Kerman Province fauna. The current study seeks to determine the fauna of medically important scorpions in northern parts of ...
Mohammad Amin Gorouhi, Arman Izadian, Mulood Mohammadi Bavani, Alireza Sanei-Dehkordi, Amir Mohammad Habibi, Godwin Nutifafa Gidiglo, Abbas Aghaei Afshar, Seyed Massoud Madjdzadeh, Saideh Yousefi, Leila Shirani-Bidabadi, Yaser Salim Abadi, Hossein Barahoei, Ismaeil Alizadeh   +12 more
doaj   +1 more source

Functional characterization and analgesic effects of mixed cannabinoid receptor/T-type channel ligands

Molecular Pain, 2011
Background Both T-type calcium channels and cannabinoid receptors modulate signalling in the primary afferent pain pathway. Here, we investigate the analgesics activities of a series of novel cannabinoid receptor ligands with T-type calcium channel ...
You Haitao, Gadotti Vinicius M, Petrov Ravil R, Zamponi Gerald W, Diaz Philippe   +4 more
doaj   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Melanocyte homeostasis in vivo tolerates Rb1 loss in a developmentally independent fashion

, 2010
There has been uncertainty regarding the precise role that the pocket protein Rb1 plays in murine melanocyte\ud homeostasis. It has been reported that the TAT-Cre mediated loss of exon 19 from a floxed Rb1 allele causes\ud melanocyte apoptosis in vivo ...
Kay, GF, Walker, Graeme J., Kay, Graham F., Wayne A. Schroder, Mould, AW, Schroder, WA, Ian D. Tonks, Arne W. Mould, Hayward, NK, Tonks, ID, Graeme J. Walker, Tonks, Ian D., Bosenberg, Marcus, Mould, Arne W., Bosenberg, M, Schroder, Wayne A., Hacker, Elke, Hacker, E, Elke Hacker, Hayward, Nicholas K., Walker, GJ, Marcus Bosenberg, Nicholas K. Hayward, Graham F. Kay   +23 more
core   +1 more source

Identification of potentially actionable genetic variants in epithelial ovarian cancer: a retrospective cohort study

npj Precision Oncology
Ovarian cancer is the most lethal gynecologic malignancy, mainly due to late-stage diagnosis, frequent recurrences, and eventually therapy resistance.
Charlotte Fieuws, Joni Van der Meulen, Kristiaan Proesmans, Emiel A. De Jaeghere, Siebe Loontiens, Jo Van Dorpe, Philippe Tummers, Hannelore Denys, Koen Van de Vijver, Kathleen B. M. Claes   +9 more
doaj   +1 more source