Results 1 to 10 of about 52,206 (120)

How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation. [PDF]

open access: yesPLoS Computational Biology, 2013
Osteosarcomas (OS) are complex bone tumors with various genomic alterations. These alterations affect the expression and function of several genes due to drastic changes in the underlying gene regulatory network.
Kathrin Poos   +5 more
doaj   +1 more source

Serum Interleukins as Potential Prognostic Biomarkers in HBV-Related Acute-on-Chronic Liver Failure

open access: yesMediators of Inflammation, 2022
Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is relatively common in China and has complex pathogenesis, difficult clinical treatment, and poor prognosis. Immune status is an important factor affecting ACLF prognosis.
Lili Zhang   +7 more
doaj   +1 more source

Korean Red Ginseng extract induces angiogenesis through activation of glucocorticoid receptor

open access: yesJournal of Ginseng Research, 2017
Background: Our previous studies have demonstrated that ginsenoside-Rg1 can promote angiogenesis in vitro and in vivo through activation of the glucocorticoid receptor (GR).
Wai-Nam Sung   +4 more
doaj   +1 more source

Electrogenicity accompanies photoreduction of the iron-sulfur clusters FA and FB in photosystem I [PDF]

open access: yes, 1998
Photovoltage responses accompanying electron transfer on the acceptor side of photosystem I (PS I) were investigated in proteoliposomes containing PS I complexes from the cyanobacterium Synechococcus sp. PCC 6301 using a direct electrometrical technique.
Brettel   +23 more
core   +2 more sources

Correlation of Low Levels of α-1 Antitrypsin and Elevation of Neutrophil to Lymphocyte Ratio with Higher Mortality in Severe COVID-19 Patients

open access: yesMediators of Inflammation, 2021
Background. Variations in COVID-19 prevalence, severity, and mortality rate remain ambiguous. Genetic or individual differences in immune response may be an explanation.
Ghazaleh Shimi   +6 more
doaj   +1 more source

Soluble IL-2 Receptor in Dermatomyositis: Its Associations with Skin Ulcers and Disease Activity

open access: yesMediators of Inflammation, 2020
Objective. To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM). Methods. Serum sIL-2R levels were measured in 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid ...
Linrong He   +6 more
doaj   +1 more source

Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects

open access: yesMediators of Inflammation, 2016
The cytokine erythropoietin (EPO) stimulates proliferation and differentiation of erythroid progenitor cells. Moreover, EPO has neuroprotective, anti-inflammatory, and antioxidative effects, but the use of EPO as a neuroprotective agent is hampered by ...
Oksana Dmytriyeva   +3 more
doaj   +1 more source

The development dynamics and spreading peculiarities of the pathological process in the retroperitonael space in acute pancreatitis

open access: yesPatologìâ, 2015
Despite rapid development of medicine, acute pancreatitis (AP) is still a problem. Aim. To evaluate pathological changes of retroperitoneal space (RS), the results of ultrasound research, computed tomography and laparoscopy were studied in 62 patients
V. V. Ganzhy   +3 more
doaj   +1 more source

Effect of Tityus serrulatus venom on cytokine production and the activity of murine macrophages

open access: yesMediators of Inflammation, 2002
The purpose of this study was to investigate the effects of Tityus serrulatus venom (TSV) on murine peritoneal macrophages evaluated in terms of activation. The effects of crude TSV were analysed by detection of cytokines, oxygen intermediate metabolites
Vera L. Petricevich
doaj   +1 more source

Pathological changes in the structures of the blood-brain barrier in acute cerebral circulatory disorders

open access: yesPatologìâ, 2012
Morphological changes of the blood-brain barrier were investigated in case of an acute brain disturbed circulation. Autocontrol of vessels with their dilatation and formation of aggregation from formal elements were shown from the onset of the disease ...
S.І. Tertyshny, V.E. Gulenko
doaj   +1 more source

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