Results 51 to 60 of about 177,602 (172)
Mediators of Inflammation, 2014 Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis (MS) in which activated T cell and neutrophil interactions lead to neuroinflammation.
Dagmara Weronika Wojkowska +4 more
doaj +1 more source
Advances in Double‐Stranded DNA Targeting Technologies
Exploration, Volume 6, Issue 1, February 2026.Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen +8 more
wiley +1 more source
Introduction: Better treatments for ovarian cancer are needed to eliminate residual peritoneal disease after initial debulking surgery. The present study evaluated Trastuzumab to deliver Pb-214/Bi-214 for targeted alpha therapy (TAT) for HER2-positive ...
Mike Zamiara (17842874) +10 more
core +1 more source
, 2019 Acute liver injury (ALI) induced by acetaminophen (APAP) is the main cause of drug-induced liver injury. Previous reports indicated liver failure could be alleviated by saponins (ginsenosides) from Panax ginseng against APAP-induced inflammatory ...
Jiang, Shuang +9 more
core +1 more source
Myostain is involved in ginsenoside Rb1-mediated anti-obesity
, 2022 Obesity, one of the major public health problems worldwide, has attracted increasing attention. Ginsenoside Rb1 is the most abundant active component of Panax ginseng C.A.Mey (Araliaceae) and is reported to have beneficial effects on obesity and diabetes.
Gui-Jun Liu (12698369) +9 more
core +1 more source
Diagnostic PathologyBackground Crizotinib, an oral first-generation tyrosine kinase inhibitor (TKI), is superior to systemic chemotherapy for the treatment of non-small cell lung cancer (NSCLC) with positive rearrangement of anaplastic lymphoma kinase (ALK).
Peng Zhang +4 more
doaj +1 more source
Susceptibility of lung epithelium to neutrophil elastase: protection by native inhibitors
Mediators of Inflammation, 1997 The development of emphysema is thought to be due to an imbalance of proteases (especially neutrophil elastase [NE]) and antiproteases with loosening of the respiratory epithelium as an early event.
L. Bingle +5 more
doaj +1 more source
Epiphyseal Primary Diffuse Large B-Cell Lymphoma of Bone
Case Reports in Pathology, 2018 Primary lymphoma of bone (PLB) confined to the epiphysis has only been described in four other patients. Due to the rarity of this entity, diagnosis has often been delayed, leading to mismanagement with adverse clinical consequences.
Shachar Kenan +4 more
doaj +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Sequences of acetyl CoA carboxylase promoter for tumour necrosis factor action
Mediators of Inflammation, 1993 Tumour necrosis factor (TNF) inhibits the accumulation of acetyl CoA carboxylase (ACC) mRNA by decreasing the rate of ACC gene transcription. The ACC mRNA species found in 30A5 cells are generated from promoter II and TNF inhibits the accumulation of ...
Keerang Park +2 more
doaj +1 more source