Results 51 to 60 of about 53,919 (139)

ST2 myocardial stress marker research in patients with obstructive sleep apnea and gastroesophageal reflux disease

Patologìâ, 2020
Objective – To investigate the ST2 marker dynamics in the serum in patients with combined obstructive sleep apnea (OSA) and gastroesophageal reflux disease (GERD) and analyze its relationship with myocardial dysfunction. Materials and methods.
V. I. Kryvenko , O. A. Svityltska
doaj   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, Volume 13, Issue 36, 29 June 2026.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Patients With Stage III PLCNEC Advocated for Radiotherapy Combined With Chemotherapy While With Stage IV Focus on Individualized Management: Evidence From SEER

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background PLCNEC is a rare and highly aggressive lung cancer with a poor prognosis. Multimodal therapy, primarily chemotherapy‐based, is the standard for advanced PLCNEC, but the role of radiotherapy remains unclear. Methods We analyzed 1086 PLCNEC patients receiving chemotherapy from the Surveillance, Epidemiology, and End Results (SEER ...
Yuze Zhao, Guantong Liu, Haitao Li, Yu Li, Ting Lin, Zefeng Xie   +5 more
wiley   +1 more source

Salmonella-induced changes in the gut microbiota and immune response genes transcriptome during administration of vancomycin and Bacteroides fragilis

Patologìâ, 2017
The aim. To study Salmonella-induced changes in the intestinal wall microbiota, the expression of Salmonella effector proteins SipA, SopB, SopE2 and transcriptional activity of genes FFAR2, Foxp3, RORγt in rat GALT during administration of vancomycin and
Yu. V. Bukina, A. M. Kamyshnyi, N. N. Polishchuk   +2 more
doaj   +1 more source

Influence of oxidative stress on cardiovascular parameters in patients with combined flow of chronic obstructive pulmonary disease and arterial hypertension

Patologìâ, 2013
Introduction. It is well known that active forms of oxygen, such as hydrogen peroxide, superoxide anion, hydroxyl radical and others are involved in different pathological conditions, such as cell necrosis, senescence, apoptosis, autophagy ...
V. G. Deinega , V. V. Kryvenko
doaj   +1 more source

Ductular reaction or hepatic reparative complex: immunohistochemical features in liver cirrhosis in patients with chronic hepatitis

Patologìâ, 2018
Until recently, a discussion about the mechanisms of development and the biological role of the ductular reaction, which develops in patients with chronic liver diseases continues among hepatologists and pathomorphologists. Purpose of the study.
V. A. Tumanskiy , S. V. Fen’
doaj   +1 more source

Age clinical and laboratory features of primary Epstein-Barr viral infection in children

Patologìâ, 2020
Aim: to delineate the clinical presentation and laboratory profile of primary Epstein-Barr viral infection (EBVI) in children. Materials and methods. A retrospective study was conducted on the demographic, clinical and laboratory data of 104 children ...
O. V. Konakova, O. V. Usachova, Ye. A. Silina, T. M. Pakholchuk, O. A. Dralova   +4 more
doaj   +1 more source

The role in thanatogenesis of generalized brain edema in ischemic cerebral infarction (computer-morphometric research)

Patologìâ, 2012
This work presents the results of computer-morphometric study of perivascular and pericellular free (oedematous) spaces in brain cortex at death from the ischemic cerebral infarction and from reasons unconnected directly with cerebral pathology.
E. A. Dyadyk
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Myocardial remodeling and arterial stiffness depending on aldosterone level in patients with chronic kidney disease and arterial hypertension

Patologìâ, 2019
The aim. To analyze the relationship between serum aldosterone levels and myocardial remodeling and changes in elastic properties of arteries in patients with chronic kidney disease (CKD) and hypertension (AH). Materials and methods. A cross-secitonal
O. V. Kuryata, V. V. Semenov
doaj   +1 more source