Results 91 to 100 of about 20,257 (224)

RBP4 and THBS2 are serum biomarkers for diagnosis of colorectal cancer

Oncotarget, 2017
The potential role of serum RBP4 and THBS2 as biomarker in colorectal cancer (CRC) diagnosis has never been studied. We investigated in large sample using quantitative ELISA method to explore whether serum RBP4 and THBS2 can act as biomarkers for CRC diagnosis.
Weiqiang Fei, Li Chen, Jiaxin Chen, Qinglan Shi, Lumin Zhang, Shuiping Liu, Lingfei Li, Lili Zheng, Xiaotong Hu   +8 more
openalex   +4 more sources

Chronic silencing of subsets of cortical layer 5 pyramidal neurons has a long‐term influence on the laminar distribution of parvalbumin interneurons and the perineuronal nets

Journal of Anatomy, Volume 246, Issue 4, Page 479-504, April 2025.
Chronic silencing of subsets of layer 5 projection neurons has distinct effects on the laminar distribution of PV interneurons and the perineuronal nets in the adult primary motor and somatosensory cortex. Abstract Neural networks are established throughout cortical development, which require the right ratios of glutamatergic and GABAergic neurons ...
Florina P. Szabó, Veronika Sigutova, Anna M. Schneider, Anna Hoerder‐Suabedissen, Zoltán Molnár   +4 more
wiley   +1 more source

The relationship between NAFLD and retinol-binding protein 4 - an updated systematic review and meta-analysis

Lipids in Health and Disease, 2023
Purpose Retinol-binding protein 4 (RBP4) has been considered to be related to metabolic related diseases, such as hyperuricemia, obesity, and diabetes mellitus.
Rui Hu, Xiaoyue Yang, Xiaoyu He, Guangyao Song   +3 more
doaj   +1 more source

Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases

Obesity Reviews, EarlyView.
ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar, Joanna Razafiarison, Fawaz Alzaid, Fahd Al‐Mulla, Rasheed Ahmad   +4 more
wiley   +1 more source

Serum retinol‐binding protein 4 as a predictor of cardiovascular events in elderly patients with chronic heart failure

ESC Heart Failure, 2020
Aims RBP4 is an adipokine with adverse effects on cardiovascular system. Increased circulating retinol‐binding protein 4 (RBP4) has been linked to chronic heart failure (CHF).
Xiu‐Zhen Li, Kang‐Zhen Zhang, Jian‐Jun Yan, Li Wang, Yue Wang, Xi‐Yu Shen, Hui‐Xian Sun, Li Liu, Can Zhao, Hui‐Wei He, Lian‐Sheng Wang, Wei Gao, Xiang Lu   +12 more
doaj   +1 more source

Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression

Journal of Lipid Research, 2022
Hepatocytes secrete retinol-binding protein 4 (RBP4) into circulation, thereby mobilizing vitamin A from the liver to provide retinol for extrahepatic tissues. Obesity and insulin resistance are associated with elevated RBP4 levels in the blood. However,
Julia S. Steinhoff, Carina Wagner, Ulrike Taschler, Sascha Wulff, Marie F. Kiefer, Konstantin M. Petricek, Sylvia J. Wowro, Moritz Oster, Roberto E. Flores, Na Yang, Chen Li, Yueming Meng, Manuela Sommerfeld, Stefan Weger, Andrea Henze, Jens Raila, Achim Lass, Michael Schupp   +17 more
doaj   +1 more source

Extracellular Vesicles: Biology, Intercellular Communication and Therapeutic Potential in Diabetes

Advanced Therapeutics, Volume 9, Issue 2, February 2026.
Exosome packaging in diabetes mellitus is depicted. Induced expression levels of RBP4, WNT related proteins, TGFB1, BMPs, VEGFs, STAT3, Calpain2 and altered expression levels of microRNAs in the exosomes are responsible for the inflammatory actions, defective central metabolism, myofibroblasts proliferation, dysregulated cell migration, cell ...
Swayam Prakash Srivastava, Lydia Herrmann, Eden Ozkan, Abhiram Kunamneni, Vinamra Swaroop, Geetika Nehra, Rohit Srivastava, Pratima Tripathi, Ken Inoki, Julie E. Goodwin   +9 more
wiley   +1 more source

Determination of FABP4, RBP4 and the MMP-9/NGAL complex in the serum of women with breast cancer

Oncology Letters, 2020
Breast cancer is the most common type of cancer in females and is the leading cause of cancer-associated death among women, worldwide. The present study aimed to measure the serum levels of fatty acid-binding protein 4 (FABP4), retinol binding protein 4 (
D. Tsakogiannis, E. Kalogera, F. Zagouri, E. Zografos, Dimitris Balalis, G. Bletsa   +5 more
semanticscholar   +1 more source

Assessment of Serum Retinol Binding Protein 4 in Patients with Hepatocellular Carcinoma [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Retinol Binding Protein 4 (RBP4) may be indirectly involved in the induction of carcinogenesis as it was identified as a key regulator of insulin resistance in obesity and diabetes.
Yehia Mohamed El Shazly, Mohamed Abd El Moghny, Reham Ezzat Al Swaff, Hany Ali Hussein, Hany Samir Rasmy, Moataz Aly Ahmad   +5 more
doaj   +1 more source

Integrative cross‐tissue and spatially resolved single‐cell profiling uncovers tumour‐educated inflammatory remodelling of tissue‐resident macrophage ecosystem with immunotherapeutic prognostic significance in pan‐cancer

Clinical and Translational Medicine, Volume 16, Issue 2, February 2026.
Pan‐cancer analysis reveals an inflammatory phenotype remodeling of tissue‐resident macrophages (iTRM) in the tumor microenvironment, which is associated with immunosuppression. Tissue‐resident macrophages and monocyte‐derived macrophages exhibit convergent differentiation toward a similar inflammatory phenotype. iTRM‐enriched ecosystems are associated
Weikai Wang, Zibin Chen, Yuhan Huang, Zhihao Hu, Peixin Zhu, Zhuoli Huang, Jingzhi Lv, Ziru Liao, Yuhui Zheng, Chen Wei, Baibing Guan, Yin Zeng, Xinyue Zhu, Yafei Yang, Guibo Li, Xin Jin, Xi Chen, Xiao Yang, Zikun Ma, Jianhua Yin   +19 more
wiley   +1 more source