Adipokine Retinol Binding Protein 4 and Cardiovascular Diseases [PDF]
Frontiers in Physiology, 2022 The morbidity and mortality of cardiovascular diseases (CVDs) have been increasing year by year all over the world and expanding greatly to the younger population, which becomes the leading causes of death globally that threatens human life safety ...
Yanjing Ji +3 more
doaj +5 more sources
Retinol Binding Protein 4 Promotes Chondrocyte and Osteoclast Differentiation [PDF]
BiologyRetinol-binding protein 4 (RBP4), an adipokine secreted by adipose tissues, has been implicated in metabolic inflammation and insulin resistance. Type 2 diabetes (T2D) is a recognized risk factor for osteoarthritis, with both conditions characterized by ...
Adam Quincey +2 more
doaj +4 more sources
Retinol and retinol binding protein 4 levels and COVID-19: a Mendelian randomization study [PDF]
BMC Pulmonary MedicineBackground The Corona Virus Disease 2019 (COVID-19) pandemic has struck globally. Whether the related proteins of retinoic acid (RA) signaling pathway are causally associated with the risk of COVID-19 remains unestablished.
Haixia Wang +5 more
doaj +4 more sources
Retinol-binding protein-4 and nonalcoholic fatty liver disease [PDF]
Chinese Medical Journal, 2022 . Nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common as the global economy grows and living standards improve. Timely and effective preventions and treatments for NAFLD are urgently needed.
Hangkai Huang, Chengfu Xu, Yuanyuan Ji
doaj +4 more sources
Electrochemical Aptasensing Platform for the Detection of Retinol Binding Protein-4 [PDF]
BiosensorsHere, we present the results of our the electrochemical aptasensing strategy for retinol binding protein-4 (RBP-4) detection based on a thiolated aptamer against RBP-4 and 6-mercaptohexanol (MCH) directly immobilized on a gold electrode surface. The most
Kamila Malecka-Baturo +4 more
doaj +4 more sources
Retinol and Retinol Binding Protein 4 Levels and Cardiometabolic Disease Risk. [PDF]
Circ Res, 2022 Background: Despite mechanistic studies linking retinol and RBP4 (retinol binding protein 4) to the pathogenesis of cardiovascular diseases (CVD) and type 2 diabetes (T2D), epidemiological evidence is still conflicting. We investigated whether conflicting results of previous studies may be explained by differences in the ...
Schiborn C +10 more
europepmc +7 more sources
The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review. [PDF]
Int J Environ Res Public Health, 2022 Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force.
Ratajczyk K +8 more
europepmc +4 more sources
Retinol-binding protein 4 in cardiovascular diseases: mechanisms and therapeutic perspectives [PDF]
Frontiers in Cardiovascular MedicineCardiovascular diseases (CVDs) continue to be the leading cause of mortality worldwide, highlighting the need for enhanced diagnostic tools to enable early intervention.
Jiefang Chen +4 more
doaj +2 more sources
Association of retinol binding protein 4 with risk of gestational diabetes [PDF]
Diabetes Research and Clinical Practice, 2013 We investigated association of maternal retinol binding protein 4 (RBP4) with risk of gestational diabetes (GDM).GDM cases (N=173) and controls (N=187) were selected from among participants of a cohort study of risk factors of pregnancy complications.
Daniel Enquobahrie +2 more
exaly +3 more sources
Retinol binding protein 4 enhances cellular cholesterol uptake to facilitate influenza A virus infection [PDF]
PLoS PathogensViruses hijack host cell machinery to facilitate their own replication. Therefore, identifying key cellular factors and processes involved in viral infection is crucial for developing host-directed therapies.
Hejiao Zhao +6 more
doaj +3 more sources