Optimised expression and purification of RBP4 and preparation of anti-RBP4 monoclonal antibody
FEBS Open Bio, 2022 The expression level of retinol‐binding protein 4 (RBP4) protein is closely related to liver damage and plays an important role in the diagnosis and prognosis of cancer.
Hui Li, Min He, Lichao Yang
exaly +2 more sources
Effect of Dietary Vitamin A, Breed, and Kidney Function on the Onset of Urinary Vitamin A Excretion and the Vitamin A Transport Complex in Growing Dogs. [PDF]
J Anim Physiol Anim Nutr (Berl)ABSTRACT Vitamin A (retinol and retinyl esters) is present in substantial amounts in the urine of healthy adult dogs, but the mechanisms affecting its excretion are poorly understood. To assess whether the onset of urinary vitamin A excretion is dependent on dietary vitamin A intake, breed, and/or parameters of kidney function, 48 puppies from two ...
Raila J, Özpinar H, Schweigert FJ.
europepmc +2 more sources
RBP4 promotes denervation-induced muscle atrophy through STRA6-dependent pathway
Journal of Cachexia, Sarcopenia and MuscleBackgrounds Fat infiltration of skeletal muscle has been recognized as a common feature of many degenerative muscle disorders. Retinol binding protein 4 (RBP4) is an adipokine that has been demonstrated to be correlated with the presence and severity of ...
Xiang Lu, Yun-Feng Rui, Wei Gao
exaly +2 more sources
Biological Functions of RBP4 and Its Relevance for Human Diseases
Frontiers in Physiology, 2021 Retinol binding protein 4 (RBP4) is a member of the lipocalin family and the major transport protein of the hydrophobic molecule retinol, also known as vitamin A, in the circulation.
Julia S. Steinhoff +2 more
exaly +3 more sources
Mass spectrometry-based urinary proteomic analysis in feline chronic kidney disease. [PDF]
Physiol RepAbstract Chronic kidney disease (CKD) is highly prevalent in domestic cats (Felis catus), which might serve as a spontaneous disease model for human CKD. Urinary proteomics is a promising tool for CKD diagnosis and management; yet, minimal information is available in cats. This study aimed to explore the urinary proteome in cats with CKD and assess its
Huang JHC +3 more
europepmc +2 more sources
RBP4 interferes with tongue squamous cell carcinoma progression by inhibiting the PI3K/AKT signaling pathway and promoting macrophage M1-type polarization [PDF]
Scientific ReportsTongue squamous cell carcinoma (TSCC) is a common type of oral mucosal epithelial malignancy that can severely affect patient quality of life. Therefore, novel therapeutic strategies for TSCC are needed.
Ying Yan, Nan Miao, Xiaofeng Wang
doaj +2 more sources
Single-sequence based gFET-aptasensors for the discrimination of apo- and holo-RBP4 in human serum [PDF]
Scientific ReportsRetinol-binding protein 4 (RBP4) is a key transporter of all-trans-retinol (vitamin A), circulating in blood as either holo-RBP4 (retinol-bound) or apo-RBP4 (retinol-free).
Hu Xing +16 more
doaj +2 more sources
Hepatology, EarlyView., 2022 Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong +9 more
wiley +1 more source
Genetics Research, 2022 Backgrounds. Retinol-binding protein 4 (RBP4) is a monomeric-binding protein belonging to the lipocalin protein family, which has been reported to be dysregulated in several malignancies such as breast cancer and lung cancer.
Xinqing Deng +3 more
doaj +1 more source
Elevated Serum Retinol Binding Protein 4 is Associated with the Risk of Diabetic Cardiomyopathy
Reviews in Cardiovascular Medicine, 2022 Background: Retinol binding protein 4 (RBP4), a biomarker for insulin resistance in type 2 diabetes (DM), is increased in heart failure. This case-control study aims to determine the association between serum RBP4 levels and diabetic cardiomyopathy (DCM).
Haihua Shan +8 more
doaj +1 more source