Results 101 to 110 of about 20,257 (224)

Changes of Serum CTRP12 in Patients With Coronary Artery Disease After the Treatment of Percutaneous Coronary Intervention and Its Relationship With In‐Stent Restenosis

Clinical Cardiology, Volume 49, Issue 1, January 2026.
Serum CTRP12 levels are significantly lower in CAD patients, and significant correlate to disease severity and dynamic changes after PCI. They may serve as a potential biomarker for diagnosing CAD and predicting ISR occurrence. ABSTRACT Background C1q/tumor necrosis factor‐related protein 12 (CTRP12) plays a protective role in coronary artery disease ...
Botao Zhao, Yuchao Shen
wiley   +1 more source

Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Elevated SUA can lead to oxidative stress, endothelial dysfunction, inflammation and impaired function of adipocytes—all of which collectively impede insulin receptor activity and downstream signalling. Key pathways involved include activation of the NLRP3 inflammasome, suppression of AMPK and induction of mitochondrial dysfunction.
Nurshad Ali
wiley   +1 more source

Retinol binding protein 4 restricts PCV2 replication via selective autophagy degradation of viral ORF1 protein

Communications Biology
Autophagy is a highly conserved degradative process that has been linked to various functions, including defending host cells against pathogens. Although the involvement of autophagy in porcine circovirus 2 (PCV2) infection has become apparent, it ...
Qingbing Han, Hejiao Zhao, Meng Chen, Wenshuo Xue, Jun Li, Lei Sun, Yingli Shang   +6 more
doaj   +1 more source

Retinol-binding protein 4 (RBP4) and high sensitivity C-reactive protein (hs-CRP) levels in patients with diminished ovarian reserve (DOR): a cross-sectional study

Reproductive Biology and Endocrinology, 2020
Background Antioxidant/oxidant imbalance has been reported to be related to diminished ovarian reserve (DOR). Vitamin A (retinol), a kind of antioxidant, plays a role in restoring ovarian oxidative damage, while C-reactive protein (CRP) is the classical ...
Wen Zou, Zehao Wang, Jing-sheng Xia, Jing Yang   +3 more
semanticscholar   +1 more source

Serum Retinol Levels and Risk of Asthma: Evidence From the NHANES and Mendelian Randomization

Food Frontiers, Volume 7, Issue 1, January 2026.
The results of cross‐sectional studies and MR analysis support an association between serum retinol and the prevalence of asthma in adults. Higher serum retinol levels may serve as a protective factor against asthma. ABSTRACT Given the ongoing controversy regarding the relationship between serum retinol levels and asthma, this study aims to clarify ...
Xingyang Chen, Meichen Li, Boyang Qu, Yanrong Ao, Hong Gu, Yuan Tian, Yuan Song, Weiwei Cui   +7 more
wiley   +1 more source

Serum retinol-binding protein 4 levels in polycystic ovary syndrome

Endocrine Connections, 2019
Objective: Serum levels of retinol-binding protein 4 (RBP4), an adipokine thought to affect systemic insulin sensitivity, were compared between women with polycystic ovary syndrome (PCOS) and non-PCOS controls to evaluate the association of RBP4 with ...
Shilpa Lingaiah, Laure Morin-Papunen, Terhi Piltonen, Inger Sundström-Poromaa, Elisabet Stener-Victorin, Juha S Tapanainen   +5 more
doaj   +1 more source

Exercise training alters postprandial serum RBP4 in older adults

The FASEB Journal, 2012
Serum retinol binding protein 4 (sRBP4) is a specific carrier for retinol and an adipokine that has been associated with insulin resistance. The purpose of this study was to determine the effect of six months of endurance training on fasting and postprandial sRBP4 concentrations in response to ingestion of a high‐fat, high‐calorie ...
Josef Brandauer, Edward Paul Weiss, Danielle Marie Berardinelli, James Michael Hagberg   +3 more
openaire   +1 more source

Retinol binding protein 4 (Rbp4) mRNA translation in hepatocytes is enhanced by activation of mTORC1.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Increased expression of the peptide hormone retinol-binding protein 4 (RBP4) has been implicated in the development of insulin resistance, type 2 diabetes, and visual dysfunction.
Jaclyn Welles, Allyson L. Toro, Siddharth Sunilkumar, S. Stevens, Carson Purnell, S. Kimball, Michael D. Dennis   +6 more
semanticscholar   +1 more source

Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia

IET Systems Biology, Volume 20, Issue 1, January/December 2026.
This study provides reference for fatty acid metabolism related potential candidate genes for sarcopenia and initially creates an effective machine learning models for further investigating the direction of the mechanism level. ABSTRACT Sarcopenia is an ageing‐related disease characterised primarily by skeletal muscle functional decline.
Ruopeng Yang, Shan Gu, Yang Li, Ping Xia
wiley   +1 more source

Unveiling the Proteomic Landscape of Extracellular Vesicles: Implications for Neurodegeneration and Neuroprotection

Journal of Neurochemistry, Volume 170, Issue 1, January 2026.
Extracellular vesicles (EVs) are tiny, membrane‐covered packets that cells naturally release to send molecular information to one another. In the brain, they function as couriers that move proteins, lipids, and other signals between neurons, glial cells, and the blood–brain barrier.
Berenice N. Bernal‐Vicente, Isaac Ponce, Emmanuel Ríos‐Castro, Perla Moreno‐Castilla, Luis B. Tovar‐y‐Romo   +4 more
wiley   +1 more source