Results 1 to 10 of about 196,738 (50)

Survival Analysis and Correlates with Molecular Epidemiology: 10-year Retrospective Series of High-Grade Glioma in Pakistan

Journal of Cancer and Allied Specialties, 2023
Introduction: High-grade gliomas are malignant, recurring primary CNS tumors requiring extensive postoperative chemotherapy and radiation treatment. Isocitrate dehydrogenase (IDH), 1p19q, and ATRX mutations significantly influence survival and response ...
Mashal Shah, Saad Bin Anis, Irfan Yousaf, Mohammad Hamza Bajwa   +3 more
doaj   +1 more source

A Rare Case of Primary Malignant Melanoma of Cervical Spine having Extramedullary Intradural Origin: A Single Case Report and Literature Review

Journal of Cancer and Allied Specialties, 2023
Introduction: Primary spinal malignant melanoma (PSMM) of extra medullary intradural origin is a rare malignant condition with limited current literature regarding its clinical course, magnetic resonance imaging (MRI) findings, treatment strategies and ...
Irfan Haider, Sarah Khan, Fawad Ul Qamar, Yasir Inam, Kashmala Gul, Iftikhar Ali Rana   +5 more
doaj   +1 more source

Chemotherapy-free radiotherapy combined with immune checkpoint inhibitors: a new regimen for locally advanced non-small cell lung cancer?

Cancer Biology & Medicine, 2023
Maintenance immunotherapy after concurrent chemoradiotherapy remains the standard therapeutic approach in patients with unresectable locally advanced non-small cell lung cancer (LA-NSCLC).
Lin Ma, Liufu Deng, Jianfeng Peng, Jinming Yu, Xiangjiao Meng   +4 more
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Prognostic value of platelet-to-lymphocyte ratio in patients with unresectable hepatocellular carcinoma undergoing transarterial chemoembolization and tyrosine kinase inhibitors plus immune checkpoints inhibitors

Frontiers in Oncology
PurposeTo investigate the prognostic value of platelet-to-lymphocyte ratio (PLR) in patients with unresectable hepatocellular carcinoma (uHCC) treated with transarterial chemoembolization (TACE) and tailored tyrosine kinase inhibitors (TKIs) plus immune ...
Yiwan Guo, Wenlong Wu, Bo Sun, Tingting Guo, Keke Si, Chuansheng Zheng, Xin Li   +6 more
doaj   +1 more source

Treatment decision for recurrences in non-small cell lung cancer during or after adjuvant osimertinib: an international Delphi consensus report

Frontiers in Oncology
IntroductionOsimertinib is recommended by major guidelines for use in the adjuvant setting in patients with EGFR mutation-positive NSCLC following the significant improvement in disease-free survival observed in the Phase III ADAURA trials.
Myriam Mirza, Aseem Shrivastava, Cecile Matthews, Natasha Leighl, Calvin S. H. Ng, David Planchard, David Planchard, Sanjay Popat, Sanjay Popat, Sanjay Popat, Julia Rotow, Egbert F. Smit, Ross Soo, Masahiro Tsuboi, Fan Yang, Brendon Stiles, Christian Grohe, Yi-Long Wu   +17 more
doaj   +1 more source

Characteristics of patients with newly diagnosed hematological malignancies referred for echocardiography

Frontiers in Oncology
ObjectiveThe importance of cardio-hemato-oncology programs is increasing. The main aim of the study was to identify all coexisting cardiovascular disorders in patients with new hematological malignancies referred for echocardiography during baseline ...
Jarosław Kępski, Sebastian Szmit, Ewa Lech-Marańda   +2 more
doaj   +1 more source

Triple-Negative Breast Cancer: Emerging Biomarkers for Early Diagnosis, Prognosis, and Treatment [PDF]

Middle East Journal of Cancer
Breast cancer (BC) is a heterogeneous disease characterized by significant global mortality and incidence rates. Annually, approximately 1 million cases of BC are diagnosed worldwide, with over 170,000 classified as triple-negative.
Zahra Roshanizadeh, Mohammad Reza Haghshenas, Abbas Ghaderi   +2 more
doaj   +1 more source

Combinatorial immunotherapy of N-803 (IL-15 superagonist) and dinutuximab with ex vivo expanded natural killer cells significantly enhances in vitro cytotoxicity against GD2+ pediatric solid tumors and in vivo survival of xenografted immunodeficient NSG mice

Journal for ImmunoTherapy of Cancer, 2021
Background Children with recurrent and/or metastatic osteosarcoma (OS), neuroblastoma (NB) and glioblastoma multiforme (GBM) have a dismal event-free survival (<25%). The majority of these solid tumors highly express GD2.
Patrick Soon-Shiong, Dean A. Lee, Yaya Chu, Gaurav Nayyar, Jeffrey T Safrit, Susiyan Jiang, Jeremy M. Rosenblum, Mitchell S. Cairo   +7 more
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Unilateral hippocampal sparing during whole brain radiotherapy for multiple brain metastases: narrative and critical review

Frontiers in Oncology
BackgroundThe landscape of brain metastases radiotherapy is evolving, with a shift away from whole-brain radiotherapy (WBRT) toward targeted stereotactic approaches aimed at preserving neurocognitive functions and maintaining overall quality of life. For
Petr Pospisil, Petr Pospisil, Ludmila Hynkova, Ludmila Hynkova, Lucie Hnidakova, Lucie Hnidakova, Jana Maistryszinova, Jana Maistryszinova, Pavel Slampa, Pavel Slampa, Tomas Kazda, Tomas Kazda   +11 more
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The Impact of Glutamine Mouthwash on Preventing Mucositis Following Administration of High Doses of Methotrexate in Children with Acute Lymphoblastic Leukemia: A Randomized Clinical Trial [PDF]

Middle East Journal of Cancer
Background: Acute lymphoblastic leukemia (ALL) represents the predominant childhood cancer. High-dose methotrexate is integral to leukemia treatment protocols.
Mohammad Naderisorki, Hossein Karami, Ebrahim Salehifar, Helieh Jafari   +3 more
doaj   +1 more source