Results 41 to 50 of about 343,577 (69)

Impact of standardized immunophenotyping and MRD monitoring on early mortality reduction in childhood leukemia: a step towards addressing healthcare disparities in vulnerable populations from Southern Mexico

Frontiers in Oncology
BackgroundDespite high cure rates for pediatric B-cell acute lymphoblastic leukemia (B-ALL) in high-income countries, early mortality remains unacceptably high in low- and middle-income countries (LMICs), largely due to limited access to risk-adapted ...
Laura Alfaro-Hernández, Laura Alfaro-Hernández, Dalia Ramírez-Ramírez, Rubí Romo-Rodríguez, Karen Ayala-Contreras, Ángeles del Campo-Martínez, Enrique López-Aguilar, Janet Flores Lujano, Aldo Allende-López, Erika Alarcón-Ruiz, Ma Del Rocio Banos-Lara, Ma Del Rocio Banos-Lara, Diana Casique-Aguirre, Diana Casique-Aguirre, Jesús Elizarrarás-Rivas, Javier Antonio López-Aquino, Miguel Ángel Garrido-Hernández, Daniela Olvera-Caraza, Vanessa Terán-Cerqueda, Juan Carlos Solís-Poblano, Pierre Mitchel Aristil-Chery, Enoch Alvarez-Rodríguez, Enoch Alvarez-Rodríguez, Wilfrido Herrera-Olivares, Lénica Anahí Chavez-Aguilar, Aquilino Márquez-Toledo, Lena Sarahi Cano-Cuapio, Nuria Citlalli Luna-Silva, Maria Angélica Martínez-Martell, Anabel Beatriz Ramirez-Ramirez, Juan Carlos Rodríguez-Espinosa, Daniela Medina-León, Roberto Rodríguez-Díaz, Minerva Mata-Rocha, Amanda Idaric Olivares-Sosa, Haydeé Rosas-Vargas, Juan Manuel Mejia-Arangure, Juan Manuel Mejia-Arangure, Lourdes Millán-Pérez-Peña, Rosana Pelayo, Rosana Pelayo, Juan Carlos Núñez-Enríquez   +41 more
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In silico identification of microRNAs as candidate colorectal cancer biomarkers

Tumor Biology, 2019
The involvement of microRNA in cancers plays a significant role in their pathogenesis. Specific expressions of these non-coding RNAs also serve as biomarkers for early colorectal cancer diagnosis, but their laboratory/molecular identification is ...
Adewale Oluwaseun Fadaka, Ashwil Klein, Ashley Pretorius   +2 more
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Amino acids shape the metabolic and immunologic landscape in the tumor immune microenvironment: from molecular mechanisms to therapeutic strategies

Cancer Biology & Medicine
The tumor immune microenvironment (TIME) represents a complex battlefield where metabolic competition and immune evasion mechanisms converge to drive cancer progression.
Ziyou Lin, Chang Chang, Shuyu Zhao, Lan Fang, Ping Wang   +4 more
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High expression of G-protein signaling modulator 2 in hepatocellular carcinoma facilitates tumor growth and metastasis by activating the PI3K/AKT signaling pathway

Tumor Biology, 2017
The aim of this study was to investigate the role of G-protein signaling modulator 2 in the carcinogenesis and progression of hepatocellular carcinoma. We previously showed that G-protein signaling modulator 2 was upregulated in hepatitis B virus-related
Xiao-Qin He, Yue-Feng Zhang, Jia-Jun Yu, Yuan-Yuan Gan, Na-Na Han, Mei-Xia Zhang, Wei Ge, Jun-Jian Deng, Yong-Fa Zheng, Xi-Ming Xu   +9 more
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Drugging the ‘undruggable’ KRAS: breakthroughs, challenges, and opportunities in pancreatic cancer

Cancer Biology & Medicine
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor prognosis that is driven primarily by oncogenic KRAS mutations present in > 90% of cases.
Nawaz Khan, Umar Raza, Syed Aqib Ali Zaidi, Muhadaisi Nuer, Kayisaier Abudurousuli, Yipaerguli Paerhati, Alifeiye Aikebaier, Wenting Zhou   +7 more
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Knockdown of long non-coding RNA HOXD-AS1 inhibits gastric cancer cell growth via inactivating the JAK2/STAT3 pathway

Tumor Biology, 2017
Long non-coding RNA HOXD-AS1 (HOXD cluster antisense RNA 1) has been demonstrated to be closely associated with the progression of several tumors. However, the biological function of HOXD-AS1 and the underlying molecular mechanism in gastric cancer are ...
Li Zheng, Jiangtao Chen, Zhongyong Zhou, Zhikuan He   +3 more
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UMNH:Mamm:282

, 2021
UMNH:Mamm:282 Voucher specimen study ...
UMNH VZ Staff
core  

Lactate and lactylation in breast cancer: current understanding and therapeutic opportunities

Cancer Biology & Medicine
Breast cancer (BC) has the highest prevalence among cancers specific to women, and its incidence rates are increasing in many countries. Subtypes of BC, including HER2-positive or triple-negative BC, exhibit differing treatment responses; consequently ...
Lan Huang, Xuemei Chen, Meina Yan, Ze Xiang, Jian Wu   +4 more
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Silencing of bach1 gene by small interfering RNA–mediation regulates invasive and expression level of miR-203, miR-145, matrix metalloproteinase-9, and CXCR4 receptor in MDA-MB-468 breast cancer cells

Tumor Biology, 2017
Background: Recently experimental validation of the networks revealed bach1, a basic leucine zipper transcription factor, as the common regulator of several functional invasive genes.
Reza Mohammadzadeh, Mojgan Saeid Harouyan, Seyed Mansour Ale Taha   +2 more
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Decreased long non-coding RNA SPRY4-IT1 contributes to ovarian cancer cell metastasis partly via affecting epithelial–mesenchymal transition

Tumor Biology, 2017
Long non-coding RNAs play important roles in the regulation of cellular processes including cell proliferation, differentiation, and metastasis. The dysregulation of long non-coding RNAs, such as the SPRY4-IT1 (SPRY4 intronic transcript 1), has been ...
Jing Yu, Qi Han, Yulan Cui
doaj   +1 more source