Results 21 to 30 of about 178,030 (50)

Neoadjuvant therapy for melanoma: rationale for neoadjuvant therapy and pivotal clinical trials

Therapeutic Advances in Medical Oncology, 2022
The treatment of malignant melanoma has drastically changed over the past decade with the advent of immune checkpoint blockade, targeted therapy with BRAF/MEK inhibition, and other novel therapies such as oncolytic virus intralesional therapy.
Russell G. Witt, Derek J. Erstad, Jennifer A. Wargo   +2 more
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Deep Learning Model for Intracranial Hemangiopericytoma and Meningioma Classification

Frontiers in Oncology, 2022
BackgroundIntracranial hemangiopericytoma/solitary fibrous tumor (SFT/HPC) is a rare type of neoplasm containing malignancies of infiltration, peritumoral edema, bleeding, or bone destruction.
Ziyan Chen, Ziyan Chen, Ningrong Ye, Ningrong Ye, Nian Jiang, Nian Jiang, Qi Yang, Qi Yang, Siyi Wanggou, Siyi Wanggou, Xuejun Li, Xuejun Li   +11 more
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Comparative Clinical Efficacy of ‘Concurrent Chemoradiotherapy (CCRT) and Anlotinib’ Than CCRT in Patients with Locally Advanced ESCC

Technology in Cancer Research & Treatment, 2022
Objective: Radiotherapy or chemoradiotherapy has been preferred as the clinical therapeutic modalities to combat locally advanced esophageal squamous cell carcinoma (ESCC).
Gang Wang MD, Narasimha M. Beeraka MRes, PhD, Wenjing Xiao MD, PhD, Yaowen Zhang MD, Nannan Xue MD, Gongan Chen MD, Junqi Liu MD, PhD, Yang Liu MD   +7 more
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α-Hederin Inhibits the Proliferation of Hepatocellular Carcinoma Cells via Hippo-Yes-Associated Protein Signaling Pathway

Frontiers in Oncology, 2022
AimsYes-associated protein (YAP), a downstream protein in the Hippo signaling pathway, plays an important role in tumor proliferation, including in hepatocellular carcinoma (HCC).
Tongqing Chen, Dongdong Sun, Qijuan Wang, Tingting Zhou, Jiani Tan, Changliang Xu, Haibo Cheng, Weixing Shen   +7 more
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A Comprehensive Evaluation of the Application of the Halcyon(2.0) IMRT Technique in Long-Course Radiotherapy for Rectal Cancer

Technology in Cancer Research & Treatment, 2022
Objective: To evaluate if the Halcyon(2.0) Intensity Modulation Radiotherapy (IMRT) technique has an advantage in the long-course rectal cancer radiotherapy. Methods: A total of 20 clinical IMRT plans of Halcyon(2.0) for long-course (2Gy in 25 fractions)
Jiajun Zheng MSc, Yuqing Xia MSc, Li Sun BSc   +2 more
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The Aryl Hydrocarbon Receptor in the Pathogenesis of Environmentally-Induced Squamous Cell Carcinomas of the Skin

Frontiers in Oncology, 2022
Cutaneous squamous cell carcinoma (SCC) is one of the most frequent malignancies in humans and academia as well as public authorities expect a further increase of its incidence in the next years.
Christian Vogeley, Katharina M. Rolfes, Jean Krutmann, Thomas Haarmann-Stemmann   +3 more
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Integrated Bioinformatics Analysis and Validation of the Prognostic Value of RBM10 Expression in Hepatocellular Carcinoma

Cancer Management and Research, 2022
Shu-Jie Pang,1,* Zhe Sun,1,* Wen-Feng Lu,1,* Hui Si-Ma,1 Zhi-Peng Lin,2 Yang Shi,1 Ying-Cheng Yang,1 Xi-Jun Zhao,1 Guang-Shun Yang,1 Guang-Zhi Jin,3 Ning Yang1 1Department V of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second ...
Pang SJ, Sun Z, Lu WF, Si-Ma H, Lin ZP, Shi Y, Yang YC, Zhao XJ, Yang GS, Jin GZ, Yang N   +10 more
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Combination of ShuangDan Capsule and Sorafenib Inhibits Tumor Growth and Angiogenesis in Hepatocellular Carcinoma Via PI3K/Akt/mTORC1 Pathway

Integrative Cancer Therapies, 2022
Hepatocellular carcinoma (HCC) is a high mortality liver cancer. The existing treatments (transplantation, chemotherapy, and individualized treatment) with limitations.
Wenbo Ding PhD, Xiuwei Chen PhD, Licheng Yang Master, Yaping Chen PhD, Jie Song PhD, Weiquan Bu PhD, Bin Feng PhD, Meng Zhang Master, Yi Luo PhD, Xiaobin Jia PhD, Liang Feng PhD   +10 more
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Immune Infiltration and Clinical Outcome of Super-Enhancer-Associated lncRNAs in Stomach Adenocarcinoma

Frontiers in Oncology, 2022
Super-enhancers (SEs) comprise large clusters of enhancers that highly enhance gene expression. Long non-coding RNAs (lncRNAs) tend to be dysregulated in cases of stomach adenocarcinoma (STAD) and are vital for balancing tumor immunity.
Li Peng, Li Peng, Jiang-Yun Peng, Jiang-Yun Peng, Dian-Kui Cai, Dian-Kui Cai, Yun-Tan Qiu, Yun-Tan Qiu, Qiu-Sheng Lan, Qiu-Sheng Lan, Jie Luo, Jie Luo, Bing Yang, Bing Yang, Hai-Tao Xie, Ze-Peng Du, Xiao-Qing Yuan, Xiao-Qing Yuan, Yue Liu, Dong Yin, Dong Yin   +20 more
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CAF-Associated Paracrine Signaling Worsens Outcome and Potentially Contributes to Chemoresistance in Epithelial Ovarian Cancer

Frontiers in Oncology, 2022
BackgroundHigh-grade serous ovarian cancer (HGSOC) is the predominant and deadliest form of ovarian cancer. Some of its histological subtypes can be distinguished by frequent occurrence of cancer-associated myofibroblasts (CAFs) and desmoplastic stroma ...
Michael Wessolly, Elena Mairinger, Sabrina Borchert, Agnes Bankfalvi, Pawel Mach, Kurt Werner Schmid, Rainer Kimmig, Paul Buderath, Fabian Dominik Mairinger   +8 more
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