Results 31 to 40 of about 199,364 (50)

Dysregulated cancer cell transdifferentiation into erythrocytes is an additional metabolic stress in hepatocellular carcinoma

Tumor Biology, 2018
A number of human and canine hepatocellular carcinoma tissues showed clear signs of hypoxia indicated by HIF1α-activation and the presence of large clusters of cells resembling erythrocytes at different stages of nuclear elimination without any defined ...
Abigail Hughes, Gurtej K Dhoot
doaj   +1 more source

Impact of Oncological Treatment on Quality of Life in Patients with Head and Neck Malignancies: A Systematic Literature Review (2020–2025)

Current Oncology
Background: Quality of life (QoL) is a critical indicator in assessing the success of oncological treatments for head and neck malignancies, reflecting their impact on physiological functions and psychosocial well-being beyond mere survival.
Raluca Grigore, Paula Luiza Bejenaru, Gloria Simona Berteșteanu, Ruxandra Ioana Nedelcu-Stancalie, Teodora Elena Schipor-Diaconu, Simona Andreea Rujan, Bianca Petra Taher, Șerban Vifor Gabriel Berteșteanu, Bogdan Popescu, Irina Doinița Popescu, Alexandru Nicolaescu, Anca Ionela Cîrstea, Catrinel Beatrice Simion-Antonie   +12 more
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Sporamin induces apoptosis and inhibits NF-κB activation in human pancreatic cancer cells

Tumor Biology, 2017
Sporamin, a Kunitz-type trypsin inhibitor (TI) from sweet potato tuberous roots, has demonstrated anti-tumor activity through poorly defined mechanisms. Furthermore, the effects of sporamin on pancreatic cancer have not been explored.
Cuijuan Qian, Xiaoying Chen, Yongxiao Qi, Sheng Zhong, Xinyan Gao, Wenjun Zheng, Zhixiang Mao, Jun Yao   +7 more
doaj   +1 more source

Insights into the Prognostic Efficacy of the Geriatric Nutritional Risk Index for Nasopharyngeal Carcinoma in the Era of Volumetric Modulated Arc Therapy: A Nomogram for Predicting Long-Term Survival Outcomes

Current Oncology
Background: The geriatric nutritional risk index (GNRI), a composite metric of serum albumin and body weight, has emerged as a prognostic tool in various cancers.
Xiang Lin, Wei Wang, Jianming Ding, Zhaodong Fei, Chuanben Chen   +4 more
doaj   +1 more source

Association of mitochondrial copy number variation and T16189C polymorphism with colorectal cancer in North Indian population

Tumor Biology, 2017
Globally, colorectal cancer is the third most common type of cancer. Genetic instability leading to cancer development is one of the major causes for development of cancer.
Bhupender Kumar, Zafar Iqbal Bhat, Savita Bansal, Sunil Saini, Afreen Naseem, Khushnuma Wahabi, Archana Burman, Geeta Trilok Kumar, Sundeep Singh Saluja, M Moshahid Alam Rizvi   +9 more
doaj   +1 more source

DCP as a biomarker for TACE efficacy in hepatocellular carcinoma

Frontiers in Oncology
IntroductionPrimary hepatocellular carcinoma (PHC) requires advanced diagnostic and therapeutic strategies. While transcatheter arterial chemoembolization (TACE) is a cornerstone treatment, efficacy assessment remains challenging.MethodsWe ...
Hui Xie, Youwei Li, Jie Yang, Yuwei Tan, Jin Xu, Xiao Yang   +5 more
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Periostin promotes migration and invasion of renal cell carcinoma through the integrin/focal adhesion kinase/c-Jun N-terminal kinase pathway

Tumor Biology, 2017
Periostin (POSTN) is an extracellular matrix protein which is overexpressed in a variety of cancers and has been related to tumorigenesis of renal cell carcinoma.
Sun Chuanyu, Zhu Yuqing, Xu Chong, Xia Guowei, Zhao Xiaojun   +4 more
doaj   +1 more source

Impact of standardized immunophenotyping and MRD monitoring on early mortality reduction in childhood leukemia: a step towards addressing healthcare disparities in vulnerable populations from Southern Mexico

Frontiers in Oncology
BackgroundDespite high cure rates for pediatric B-cell acute lymphoblastic leukemia (B-ALL) in high-income countries, early mortality remains unacceptably high in low- and middle-income countries (LMICs), largely due to limited access to risk-adapted ...
Laura Alfaro-Hernández, Laura Alfaro-Hernández, Dalia Ramírez-Ramírez, Rubí Romo-Rodríguez, Karen Ayala-Contreras, Ángeles del Campo-Martínez, Enrique López-Aguilar, Janet Flores Lujano, Aldo Allende-López, Erika Alarcón-Ruiz, Ma Del Rocio Banos-Lara, Ma Del Rocio Banos-Lara, Diana Casique-Aguirre, Diana Casique-Aguirre, Jesús Elizarrarás-Rivas, Javier Antonio López-Aquino, Miguel Ángel Garrido-Hernández, Daniela Olvera-Caraza, Vanessa Terán-Cerqueda, Juan Carlos Solís-Poblano, Pierre Mitchel Aristil-Chery, Enoch Alvarez-Rodríguez, Enoch Alvarez-Rodríguez, Wilfrido Herrera-Olivares, Lénica Anahí Chavez-Aguilar, Aquilino Márquez-Toledo, Lena Sarahi Cano-Cuapio, Nuria Citlalli Luna-Silva, Maria Angélica Martínez-Martell, Anabel Beatriz Ramirez-Ramirez, Juan Carlos Rodríguez-Espinosa, Daniela Medina-León, Roberto Rodríguez-Díaz, Minerva Mata-Rocha, Amanda Idaric Olivares-Sosa, Haydeé Rosas-Vargas, Juan Manuel Mejia-Arangure, Juan Manuel Mejia-Arangure, Lourdes Millán-Pérez-Peña, Rosana Pelayo, Rosana Pelayo, Juan Carlos Núñez-Enríquez   +41 more
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In silico identification of microRNAs as candidate colorectal cancer biomarkers

Tumor Biology, 2019
The involvement of microRNA in cancers plays a significant role in their pathogenesis. Specific expressions of these non-coding RNAs also serve as biomarkers for early colorectal cancer diagnosis, but their laboratory/molecular identification is ...
Adewale Oluwaseun Fadaka, Ashwil Klein, Ashley Pretorius   +2 more
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Amino acids shape the metabolic and immunologic landscape in the tumor immune microenvironment: from molecular mechanisms to therapeutic strategies

Cancer Biology & Medicine
The tumor immune microenvironment (TIME) represents a complex battlefield where metabolic competition and immune evasion mechanisms converge to drive cancer progression.
Ziyou Lin, Chang Chang, Shuyu Zhao, Lan Fang, Ping Wang   +4 more
doaj   +1 more source