Results 31 to 40 of about 96,018 (50)

Bronchial thermoplasty in asthma: current perspectives

Journal of Asthma and Allergy, 2015
Balaji Laxmanan, D Kyle Hogarth Section of Pulmonary and Critical Care Medicine, University of Chicago Medicine, Chicago, IL, USA Abstract: Bronchial thermoplasty (BT) is a novel therapy for patients with severe asthma.
Laxmanan B, Hogarth DK
doaj  

Natural killer (NK) cell mediated antibody-dependent cellular cytotoxicity (ADCC) in tumour immunotherapy with therapeutic antibodies

Frontiers in Immunology, 2013
In the last decade several therapeutic antibodies have been FDA and EMEA approved. Although their mechanisms of action in vivo is not fully elucidated, antibody-dependent cellular cytotoxicity (ADCC) mediated by natural killer (NK) cells is presumed to ...
Ursula Jördis Eva Seidel, Patrick eSchlegel, Peter eLang   +2 more
doaj   +1 more source

Natural Killer Cell Recruitment to the Lung During Influenza A Virus Infection Is Dependent on CXCR3, CCR5, and Virus Exposure Dose

Frontiers in Immunology, 2018
Natural killer (NK) cells are vital components of the antiviral immune response, but their contributions in defense against influenza A virus (IAV) are not well understood.
Lindsey E. Carlin, Emily A. Hemann, Zeb R. Zacharias, Jonathan W. Heusel, Kevin L. Legge, Kevin L. Legge   +5 more
doaj   +1 more source

Hydrogen Sulfide Reduces Myeloid-Derived Suppressor Cell-Mediated Inflammatory Response in a Model of Helicobacter hepaticus-Induced Colitis

Frontiers in Immunology, 2018
Chronic inflammation contributes to tumor initiation in colitis-associated colorectal cancer (CRC). Indeed, inflammatory bowel disease (IBD) patients show an increased risk of developing CRC.
Paola De Cicco, Theodore Sanders, Giuseppe Cirino, Kevin J. Maloy, Angela Ianaro   +4 more
doaj   +1 more source

Cholinergic stimulation prevents the development of autoimmune diabetes: Evidence for the modulation of Th17 effector cells via an IFNgamma-dependent mechanism

Frontiers in Immunology, 2016
Type I diabetes (T1D) results from T cell-mediated damage of pancreatic β-cells and loss of insulin production. The cholinergic anti-inflammatory pathway represents a physiological link connecting the central nervous and immune systems via vagus nerve ...
Junu George, Ghada Bashir, Mohammed M Qureshi, Yassir A Mohamed, Jamil Roumanos Azzi, Basel K al-Ramadi, Maria J Fernandez-Cabezudo   +6 more
doaj   +1 more source

The role of ion channels in microglial activation and proliferation – a complex interplay between ligand-gated ion channels, K+ channels and intracellular Ca2+

Frontiers in Immunology, 2015
Microglia are often referred to as the immune cells of the brain. They are most definitely involved in immune responses to invading pathogens and inflammatory responses to tissue damage.
Martin James Stebbing, Jennifer Marie Cottee, Indrajeetsinh eRana, Indrajeetsinh eRana   +3 more
doaj   +1 more source

A guide to bioinformatics for immunologists

Frontiers in Immunology, 2013
Bioinformatics includes a suite of methods, which are cheap, approachable, and many of which are easily accessible without any sort of specialized bioinformatic training. Yet, despite this, bioinformatic tools are under-utilized by immunologists. Herein,
Fiona Jane Whelan, Nicholas eYap, Michael G Surette, G. Brian eGolding, Dawn M. E. Bowdish   +4 more
doaj   +1 more source

Inflammation, innate immunity and the intestinal stromal cell niche: opportunities and challenges

Frontiers in Immunology, 2015
Stromal cells of multiple tissues contribute to immune-mediated protective responses and, conversely, the pathological tissue changes associated with chronic inflammatory disease.
Benjamin M J Owens, Benjamin M J Owens
doaj   +1 more source

Very Early-Onset Inflammatory Manifestations of X-Linked Chronic Granulomatous Disease

Frontiers in Immunology, 2017
Chronic granulomatous disease (CGD) is a rare primary immune deficiency caused by mutations in genes coding for components of the nicotinamide adenine dinucleotide phosphate oxidase, characterized by severe and recurrent bacterial and fungal infections ...
Roxane Labrosse, Jane Abou-Diab, Annaliesse Blincoe, Guilhem Cros, Thuy Mai Luu, Colette Deslandres, Martha Dirks, Laura Fazilleau, Philippe Ovetchkine, Pierre Teira, Françoise LeDeist, Françoise LeDeist, Isabel Fernandez, Fabien Touzot, Helene Decaluwe, Ugur Halac, Elie Haddad, Elie Haddad   +17 more
doaj   +1 more source

Comparison of the Asthma Health Questionnaire-33-Japan and the Short-Form 36-Item Health Survey for Measuring Quality of Life in Japanese Patients with Asthma

Allergology International, 2008
Background: The Asthma Health Questionnaire (AHQ)-Japan is useful for assessing quality of life (QOL) in Japanese patients with asthma. However, no studies have compared the AHQ-Japan to other QOL instruments.
Masato Muraki, Hideo Ichihashi, Ryuta Haraguchi, Takashi Iwanaga, Hirokazu Kubo, Yuji Tohda   +5 more
doaj   +1 more source