Results 31 to 40 of about 104,598 (50)

Sterile inflammation of peritoneal membrane caused by peritoneal dialysis: focus on the communication between immune cells and peritoneal stroma

Frontiers in Immunology
Peritoneal dialysis is a widely used method for treating kidney failure. However, over time, the peritoneal structure and function can deteriorate, leading to the failure of this therapy.
Hongyong Su, Rong Zou, Jinqi Su, Xiaocui Chen, Haijuan Yang, Ning An, Chen Yang, Jixin Tang, Huafeng Liu, Cuiwei Yao   +9 more
doaj   +1 more source

The single-dose Janssen Ad26.COV2.S COVID-19 vaccine elicited robust and persistent anti-spike IgG antibody responses in a 12-month Ugandan cohort

Frontiers in Immunology
IntroductionThe study investigation examined the immune response to the Janssen Ad26.COV2.S COVID-19 vaccine within a Ugandan cohort, specifically targeting antibodies directed against spike (S) and nucleocapsid (N) proteins.
Jennifer Serwanga, Jennifer Serwanga, Laban Kato, Gerald Kevin Oluka, Gerald Kevin Oluka, Violet Ankunda, Jackson Sembera, Claire Baine, Isaac Kitabye, Angela Namuyanja, Solomon Opio, Joseph Ssebwana Katende, Joseph Ssebwana Katende, Peter Ejou, The COVID-19 Immunoprofiling Team, The COVID-19 Immunoprofiling Team, Pontiano Kaleebu, Pontiano Kaleebu   +17 more
doaj   +1 more source

A review of lactate-lactylation in malignancy: its potential in immunotherapy

Frontiers in Immunology
Lactic acid was formerly regarded as a byproduct of metabolism. However, extensive investigations into the intricacies of cancer development have revealed its significant contributions to tumor growth, migration, and invasion.
Jinhui Zha, Jinhui Zha, Junan Zhang, Jingfen Lu, Guangcheng Zhang, Guangcheng Zhang, Mengzhan Hua, Weiming Guo, Jing Yang, Gang Fan   +9 more
doaj   +1 more source

Comparison of neoadjuvant chemotherapy or chemoradiotherapy plus immunotherapy for locally resectable esophageal squamous cell carcinoma

Frontiers in Immunology
BackgroundNeoadjuvant chemotherapy plus immunotherapy (nCT + ICIs) and neoadjuvant chemoradiotherapy plus immunotherapy (nCRT + ICIs) both induced favorable pathological response and tolerant toxicities for locally resectable esophageal squamous cell ...
Guozhen Yang, Guozhen Yang, Guozhen Yang, Haodong Yue, Haodong Yue, Xiaomin Zhang, Chufeng Zeng, Chufeng Zeng, Chufeng Zeng, Linyu Tan, Linyu Tan, Linyu Tan, Xu Zhang, Xu Zhang, Xu Zhang   +14 more
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Omalizumab for the reduction of allergic reactions to foods: a narrative review

Frontiers in Allergy
The frequency of food allergies varies between 2% and 10%, depending on characteristics including age, region, race, and method of diagnosis self-reported by patients or oral food challenges (OFCs). The most common allergies reported are tree nuts (1.2%),
Hafsa Ghouri, Ashna Habib, Zainab Nazir, Nimerta Lohana, Aymar Akilimali   +4 more
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C5a stimulation induces caspase-1 activation and mature IL-1β production in human peripheral blood mononuclear cells

Immunological Medicine
The complement component C5a contributes to the recruitment of immune cells to inflamed tissues and local inflammation. The proinflammatory cytokine interleukin (IL)-1β is also related to inflammatory disorders through inflammasome activation.
Yuya Fujita, Haruki Matsumoto, Kenji Inada, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, Takeshi Machida, Kiyoshi Migita   +12 more
doaj   +1 more source

NF9 peptide specific cytotoxic T lymphocyte clone cross react to Y453F mutation of SARS-CoV-2 virus spike protein

Immunological Medicine
The recognition by cytotoxic T cells (CTLs) is essential for the clearance of SARS-CoV-2 virus-infected cells. Several viral proteins have been described to be recognized by CTLs. Among them, the spike (S) protein is one of the immunogenic proteins.
Aiko Murai, Terufumi Kubo, Takayuki Ohkuri, Junko Yanagawa, Yuki Yajima, Akemi Kosaka, Dongliang Li, Toshihiro Nagato, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Takeshi Nagasaki, Yoshihiko Hirohashi, Hiroya Kobayashi, Toshihiko Torigoe   +14 more
doaj   +1 more source

Efficacy and safety of mycophenolate mofetil for steroid reduction in neuromyelitis optica spectrum disorder: a prospective cohort study

Immunological Medicine
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune inflammatory disease that can affect multiple generations and cause complications with long-term prednisolone treatment.
Ritsu Akatani, Norio Chihara, Shusuke Koto, Sotaro Mori, Takuji Kurimoto, Makoto Nakamura, Hisatsugu Tachibana, Yoshihisa Otsuka, Takehiro Ueda, Takashi Omori, Kenji Sekiguchi, Riki Matsumoto   +11 more
doaj   +1 more source

Synovial-tissue resident macrophages play proinflammatory functions in the pathogenesis of RA while maintaining the phenotypes in the steady state

Immunological Medicine
Synovial tissue-resident macrophages (STRMs) maintain normal joint homeostasis in a steady state. However, it is unclear whether STRMs still play homeostatic roles or change the functions in the joint of rheumatoid arthritis (RA), where infiltrating ...
Kazuhiro Kai, Hisakata Yamada, Ryosuke Tsurui, Koji Sakuraba, Kenjiro Fujimura, Shinya Kawahara, Yukio Akasaki, Hidetoshi Tsushima, Toshifumi Fujiwara, Daisuke Hara, Jun-ichi Fukushi, Shinichiro Sawa, Yasuharu Nakashima   +12 more
doaj   +1 more source

Gut‐lung axis and asthma: A historical review on mechanism and future perspective

Clinical and Translational Allergy
Background Gut microbiota are closely related to the development and regulation of the host immune system by regulating the maturation of immune cells and the resistance to pathogens, which affects the host immunity. Early use of antibiotics disrupts the
Xiu‐Ling Song, Juan Liang, Shao‐Zhu Lin, Yu‐Wei Xie, Chuang‐Hong Ke, Dang Ao, Jun Lu, Xue‐Mei Chen, Ying‐Zhi He, Xiao‐Hua Liu, Wen Li   +10 more
doaj   +1 more source