Results 21 to 30 of about 109,879 (70)

Clinical characteristics and biomarkers of severe immune checkpoint inhibitor-related pneumonitis triggered by immunotherapy followed by radiation: a case report

Frontiers in Immunology
BackgroundThe advent of immune checkpoint inhibitors (ICIs) has revolutionized the treatment landscape for tumor patients, dramatically improving survival rate. However, patients treated with immunotherapy are inevitably at risk of immune-related adverse
Yan Zhu, Jianhe Yu, Qun Ren, Xiang Wu, Hongxia Xu, Tian Tian, Jiang Liu   +6 more
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A review focuses on a neglected and controversial component of SCI: myelin debris

Frontiers in Immunology
Myelin sheath, as the multilayer dense structure enclosing axons in humans and other higher organisms, may rupture due to various injury factors after spinal cord injury, thus producing myelin debris.
Yuchen Zhou, Yuchen Zhou, Tao Xu, Tao Xu, Yiyan Zhou, Yiyan Zhou, Wei Han, Zhengchao Wu, Zhengchao Wu, Changwei Yang, Changwei Yang, Xiaoqing Chen   +11 more
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Non-coding RNAs in bladder cancer, a bridge between gut microbiota and host?

Frontiers in Immunology
In recent years, the role of gut microbiota (GM) in bladder cancer has attracted significant attention. Research indicates that GM not only contributes to bladder carcinogenesis but also influences the efficacy of adjuvant therapies for bladder cancer ...
Jun Zou, Baisheng Xu, Peiyue Luo, Tao Chen, Huanglin Duan   +4 more
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Maternal high fat diet exposure modifies amniotic fluid metabolites and expands group 3 innate lymphoid cells dependent on the maternal microbiome and MyD88-signaling

Frontiers in Immunology
BackgroundMaternal high fat diet (mHFD) exposure expands IL-17 producing group 3 innate lymphoid cells (IL17+ve ILC3) in the small intestine of neonatal murine offspring and increases their susceptibility to intestinal inflammation.
Xinying Niu, Dongmei Lu, Sana Jaleel, Suzette N. Palmer, Suzette N. Palmer, Mala Mahendroo, Xiaowei Zhan, Julie Mirpuri   +7 more
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In silico analysis for the development of multi-epitope vaccines against Mycobacterium tuberculosis

Frontiers in Immunology
As Bacille Calmette-Guérin (BCG) vaccine’s effectiveness is limited to only children, the development of new tuberculosis (TB) vaccines is being studied using several platforms, and a novel TB vaccine that overcomes this limitation is required.
Jin-Seung Yun, Jin-Seung Yun, A Reum Kim, Soo Min Kim, Eunkyung Shin, Sang-Jun Ha, Dokeun Kim, Hye-Sook Jeong   +7 more
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Telitacicept in combination with B-cell depletion therapy in MuSK antibody-positive myasthenia gravis: a case report and literature review

Frontiers in Immunology
Muscle-specific kinase (MuSK) myasthenia gravis (MG) is relatively rare and has a higher incidence of myasthenic crisis compared with other subtypes. However, there is still a lack of effective treatment for refractory MuSK MG. We report the case of a 70-
Jia Wang, Haotao Zheng, Jia Wei, Jiaping Wu, Ziyang Feng, Xueqin Chen, Yangsicheng Liu, Wenxin Qin, Xiude Qin, Fanxin Kong   +9 more
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TCR-CD3 signal strength regulates plastic coexpression of IL-4 and IFN-γ in Tfh-like cells

Frontiers in Immunology
The development of T follicular helper (Tfh) cells is an ongoing process resulting in the formation of various Tfh subsets. Despite advancements, the precise impact of T cell receptor (TCR) stimulation on this process remains incompletely understood ...
Niels J. M. Verstegen, Niels J. M. Verstegen, Tineke Jorritsma, Anja ten Brinke, Matteo Barberis, Matteo Barberis, Matteo Barberis, S. Marieke van Ham, S. Marieke van Ham   +8 more
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GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma

Frontiers in Immunology
BackgroundSex hormones and their related receptors have been reported to impact the development and progression of tumors. However, their influence on the composition and function of the tumor microenvironment is not well understood.
Yanyan Yang, Yanyan Yang, Yongchun Wang, Hao Zou, Zhixiong Li, Weibai Chen, Zhijie Huang, Yulan Weng, Xingjuan Yu, Jing Xu, Limin Zheng, Limin Zheng   +11 more
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Neutrophil-activating protein in Bacillus spores inhibits casein allergy via TLR2 signaling

Frontiers in Immunology
BackgroundMilk allergy commonly occurs in children, mainly caused by bovine-derived casein (CAS) protein. Neutrophil-activating protein (NAP) of Helicobacter pylori plays an immunomodulatory role with potential to suppress Th2-type immune responses ...
Zhuwei Liang, Zhuwei Liang, Zhuwei Liang, Chao Zhang, Xiaoyu Liu, Kaiyue Yang, Zhile Xiong, Zhile Xiong, Bingshao Liang, Jialiang Mai, Jialiang Mai, Xiaojun Xiao, Jie Liu, Pingchang Yang, Damo Xu, Damo Xu, Zhenwen Zhou, Zhenwen Zhou, Zhenwen Zhou   +18 more
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Primary Care Asthma Attack Prediction Models for Adults: A Systematic Review of Reported Methodologies and Outcomes

Journal of Asthma and Allergy
Lijun Ma,1,* Holly Tibble1,2,* 1Usher Institute, University of Edinburgh, Edinburgh, Scotland; 2Asthma UK Centre for Applied Research, Edinburgh, Scotland*These authors contributed equally to this workCorrespondence: Holly Tibble, Usher ...
Ma L, Tibble H
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