Results 1 to 10 of about 54,136 (48)

Unleashing the Potential of Oral Deliverable Nanomedicine in the Treatment of Inflammatory Bowel DiseaseSummary

Cellular and Molecular Gastroenterology and Hepatology
Inflammatory bowel disease (IBD), marked by chronic gastrointestinal tract inflammation, poses a significant global medical challenge. Current treatments for IBD, including corticosteroids, immunomodulators, and biologics, often require frequent systemic
Chunhua Yang, Kripa Sharma, Rabeya Jafrin Mow, Eunice Bolay, Anand Srinivasan, Didier Merlin   +5 more
doaj   +1 more source

Incremental increases in physiological fluid shear progressively alter pathogenic phenotypes and gene expression in multidrug resistant Salmonella

Gut Microbes
The ability of bacteria to sense and respond to mechanical forces has important implications for pathogens during infection, as they experience wide fluid shear fluctuations in the host. However, little is known about how mechanical forces encountered in
Jiseon Yang, Jennifer Barrila, Eric A. Nauman, Seth D. Nydam, Shanshan Yang, Jin Park, Ami D. Gutierrez-Jensen, Christian L. Castro, C. Mark Ott, Kristina Buss, Jason Steel, Anne D. Zakrajsek, Mary M. Schuff, Cheryl A. Nickerson   +13 more
doaj   +1 more source

Clinical study on the necessity and feasibility of routine MRCP in patients with cholecystolithiasis before LC

BMC Gastroenterology
Background In the past quite a long time, intraoperative cholangiography(IOC)was necessary during laparoscopic cholecystectomy (LC). Now magnetic resonance cholangiopancreatography (MRCP) is the main method for diagnosing common bile duct stones (CBDS ...
Xu Guo, Qing Fan, Yiman Guo, Xinming Li, Jili Hu, Zhuoyin Wang, Jing Wang, Kai Li, Nengwei Zhang, Buhe Amin, Bin Zhu   +10 more
doaj   +1 more source

The P2Y1 receptor in the colonic myenteric plexus of rats and its correlation with opioid-induced constipation

BMC Gastroenterology
This study was designed to explore the expression changes of P2Y1 receptors in the distal colonic myenteric layer of rats. An opioid induced constipation(OIC) rat model was generated by intraperitoneal (i.p) injection of loperamide.
Yuqiong Zhao, Huijuan Luo, Xiaojie Ren, Binghan Jia, Jinzhao Li, Lixin Wang, Junping Li   +6 more
doaj   +1 more source

Detecting non-alcoholic fatty liver disease and risk factors in health databases: accuracy and limitations of the ICD-10-AM

BMJ Open Gastroenterology, 2021
Objective The prevalence of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) cirrhosis is often underestimated in healthcare and administrative databases that define disease burden using International Classification of ...
Amy L Johnson, Leigh U Horsfall, Chris Moser, Elizabeth E Powell, Patricia C Valery, Kelly Lee Hayward   +5 more
doaj   +1 more source

Congenital Sucrase–Isomaltase Deficiency: Same Mutation with Different Clinical Presentations

The Turkish Journal of Gastroenterology
Background/Aims: Congenital sucrase–isomaltase deficiency is an autosomal recessive inherited disaccharidase deficiency characterized by chronic osmotic diarrhea.
Fatma İssi İrlayıcı, Burcu Güven , Murat Çakır   +2 more
doaj   +1 more source

Prognostic Value of S100 Family mRNA Expression in Hepatocellular Carcinoma

The Turkish Journal of Gastroenterology
Background/Aims: The S100 family contains more than 20 Ca2+-binding proteins that participate in numerous cellular biological processes. However, the prognostic value of individual S100s in hepatocellular carcinoma (HCC) remains unclear.
Renrui Wan, Zhenhua Tan , Hai Qian, Peng Li, Jian Zhang, Xiaofeng Zhu , Ping Xie, Lingyan Ren   +7 more
doaj   +1 more source

RAS-Selective Lethal 3-Induced Ferroptosis Promotes the Antitumor Efficiency of Anti-Programmed Cell Death Protein 1 Treatment in Colorectal Cancer

The Turkish Journal of Gastroenterology
Background/Aims: Anti-programmed cell death protein 1 (PD-1) treatment has exhibited clinical benefits in colorectal cancer (CRC). However, the low response rate of CRC to immunotherapy is an urgent problem that needs to be solved.
Shiyv Lu, Zhilu Yao, Qing Cheng, Jianping Wu, Yuanye Jiang, Hui Lin   +5 more
doaj   +1 more source

Circular RNA SNX27 Facilitates Gastric Cancer Progression By Sponging miR-638

The Turkish Journal of Gastroenterology
Background/Aims: Accumulating evidences have shown an important role of circular RNAs (circRNAs) in the tumorigenesis of gastric cancer (GC). Nevertheless, whether circSNX27 plays a role in GC remains undetermined.
Yanfeng Xi, Yu Gai, Weixing Zhang, Meihua Wang, Qian Liu, Yanzhi Bi   +5 more
doaj   +1 more source

Utility of gastroscopy in the left lateral semi-recumbent position: A blood-free coup!

Endoscopy International Open, 2023
Biswa Ranjan Patra, Sidharth Harindranath, Abu Aasim Ansari, Shubham Gupta, Chetan Saner, Shashank Pujalwar, Arun Vaidya, Ankita Singh, Mohit Aggarwal, Akash Shukla   +9 more
doaj   +1 more source