Results 131 to 140 of about 26,875 (312)

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim   +37 more
wiley   +1 more source

REVIEW ON RC COLUMN JACKETING

open access: yesInternational Journal of Engineering Applied Sciences and Technology, 2020
Bhanu Prakash P.M, Dr.Vijaya Kumar Y.M
openaire   +1 more source

Pharmacokinetic profiling of imatinib in relation to CYP3A4 activity in leukaemia patients

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Imatinib pharmacokinetics exhibit large interindividual variability because of differences in CYP3A4 activity—the main imatinib‐metabolizing enzyme. While therapeutic drug monitoring is effective, it requires steady‐state conditions and frequent sampling.
Anna Sofie Buhl Rasmussen   +14 more
wiley   +1 more source

Development of P-I diagrams for FRP strengthened RC columns

open access: yes, 2011
In this study, numerical simulations are performed to construct the Pressure-Impulse (P-I) diagrams for FRP strengthened RC columns to provide correlations between the damage levels of FRP strengthened RC columns and blast loadings. Numerical model of RC
Hao, Hong, Mutalib, A.
core  

Non-Conventional and Sustainable Retrofitting of Fire-Exposed Reinforced Concrete Columns Using Basalt Fiber–Engineered Geopolymer Composites

open access: yesBuildings
The increasing demand for sustainable and resilient construction solutions calls for the integration of innovative, non-conventional materials in structural retrofitting.
Ruba Palanivelu   +3 more
doaj   +1 more source

Evaluating effectiveness of risk minimization through healthcare professional surveys: A review of post‐authorization studies, 2022–2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Risk minimization measures (RMMs) are key regulatory tools to ensure safe medicinal product use. Regulatory guidelines recommend pre‐specifying the targets, or ‘thresholds’, for assessing RMM effectiveness. We aimed to review recent industry‐sponsored post‐authorization safety studies (PASS) that evaluated the effectiveness of RMMs ...
Kexin Zhu   +7 more
wiley   +1 more source

A data-driven prediction method for shear bearing capacity of flexural-shear type RC column based on PCC-XGB-SHAP

open access: yesCase Studies in Construction Materials
The calculation of shear bearing capacity of RC columns is crucial for seismic design and safety assessment. However, due to the complex shear mechanisms of RC columns under seismic loading and the multitude of influencing factors, there is a lack of ...
Tao Huang   +3 more
doaj   +1 more source

Validation of the ABL + DT model: An ecosystemic framework for integrating arts and digital technologies in primary education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Primary education teachers face increasing challenges in engaging diverse learners and fostering creativity, digital competence and other transversal skills, often lacking clear, practical guidance for integrating these skills into their classrooms.
Nella Escala   +2 more
wiley   +1 more source

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