Results 41 to 50 of about 1,629 (118)

Modulatory Effects of Cirsimarin on Lung Cancer A549 Cells Migration in 2D and 3D Cultures Involves Transcriptional Regulation of Metalloproteinases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.
In 2D culture, the cirsimarin (i) decreased cell viability in both assays, (ii) induced apoptosis, (iii) reduced clonogenicity, (iv) prevented cell migration, (v) induced DNA damage, and (vi) negatively modulated gene expression. In the 3D model, reductions in spheroid viability, area, and cell migration were also observed.
Anna Gabriele Prado dos Santos, Celina Yung‐Ai Lin Lee, Érica Romão Pereira, Andresa Hiromi Sakai, Diego Luís Ribeiro, Victor Antônio Silva Lima, Marcos Bispo Pinheiro Camara, Cláudia Quintino da Rocha, Sabine A. S. Langie, Ilce Mara de Syllos Cólus, Juliana Mara Serpeloni   +10 more
wiley   +1 more source

A new taxon of saurischian dinosaur from the Coelophysis Quarry of New Mexico, USA (Triassic: latest Norian or Rhaetian) highlights herrerasaurian diversity in the latest Triassic

Papers in Palaeontology, Volume 12, Issue 2, March/April 2026.
Abstract The most complete record of the earliest dinosaur lineages is from the Carnian from the higher latitudes of Pangea (e.g. present‐day Brazil, Argentina), but dinosaurian assemblages from the upper stages of the Upper Triassic are better known from the low latitudes of Pangea (present day southwestern USA).
Simba Srivastava, Sterling J. Nesbitt
wiley   +1 more source

Avaliação da razão cintura-quadril de indivíduos cardiopatas [PDF]

, 2014
Introdução: As doenças cardiovasculares são responsáveis por 16,7 milhões de mortes/ano. Alguns estudos demonstram a utilidade da relação cintura/quadril (RCQ) como indicador de localização de gordura corporal e preditor de risco coronariano.
Dias, Caroline Pieta, Zamberlan, Ana Rita, Roncada, Cristian, Tiggmann, Carlos Leandro, Fogaça, Luciano Toigo   +4 more
core   +1 more source

Balancing Harvesting and Conservation: Demographic Responses of a Threatened Palm to Anthropogenic Disturbance

Ecology and Evolution, Volume 16, Issue 1, January 2026.
Nineteen years of demographic data reveal a consistent decline of Euterpe edulis in forest fragments, highlighting the species' vulnerability. While the population shows resilience to fruit harvesting, palm heart extraction leads to a demographic collapse.
Eduardo T. B. Mendes, Rita C. Q. Portela
wiley   +1 more source

Anti‐Infective Effect of Anacardium occidentale L. Flowers Against Eskape Group Bacteria In Vitro, In Vivo, and In Silico

BioMed Research International, Volume 2026, Issue 1, 2026.
Background/Objectives The study evaluated the in vitro antibacterial activity of the ethanolic extract of Anacardium occidentale flowers (EHAo) against ESKAPE pathogens and investigated the in vivo effects of the extract in Tenebrio molitor lethally infected with Staphylococcus aureus.
Pâmela Gomes Santos, Josivan Regis Farias, Simone Batista Muniz, Danielle Cristine Gomes Franco, Ariadina Jansen Campos Fontes, Liane Maria Rodrigues Santos, Flavia Raquel Fernandes Nascimento, Claudia Quintino Rocha, Alexandra Martins dos Santos Soares, Rosane Nassar Meireles Guerra, Poorani Gurumallesh Prabu   +10 more
wiley   +1 more source

FOXP3 Polymorphism and Upregulation of the CXCL12‐CXCR4‐SNAIL Axis with High Infiltration of M2TAM by STAT3/NFKB Pathways Influence the Survival of Cervical Cancer Patients

Advanced Biology, Volume 9, Issue 12, December 2025.
This study highlights how cervical carcinoma progression is shaped by immune–tumor interactions within the TME. M2‐TAM infiltration, regulated through STAT3/NF‐κB and linked to CXCL12–CXCR4, promotes immune suppression, angiogenesis, and poor survival.
George A. Lira, Fábio M. de Azevedo, Ingrid G. S. Lins, Janaína C. O. Crispim, Giovanna A. Lira, Rômulo S. Cavalcante, Ricardo Cobucci, Carolina O. Mendes‐Aguiar, Rafaela Torres Dantas Da Silva, Vinícius E. da Silva, Ryan C. Q. Aquino, Raimundo F. Araújo Júnior   +11 more
wiley   +1 more source

Relação do índice de massa corporal, da relação cintura-quadril e da circunferência abdominal com a mortalidade em mulheres idosas: seguimento de 5 anos Relationship between body mass index, waist circumference, and waist-to-hip ratio and mortality in elderly women: a 5-year follow-up study

Cadernos de Saúde Pública, 2005
Este estudo analisa a associação entre a relação cintura-quadril (RCQ), a circunferência abdominal (CA) e o índice de massa corporal (IMC) com a mortalidade total e cardiovascular em 575 mulheres idosas ambulatoriais por um seguimento de cinco anos.
Marcos A. S. Cabrera, Maurício Wajngarten, Otávio C. E. Gebara, Jayme Diament   +3 more
doaj   +1 more source

Identifying Key Questions and Challenges in Microchimerism Biology

Advanced Science, Volume 12, Issue 48, December 29, 2025.
This study identifies key unanswered questions about microchimerism, the presence of cells from one individual living in another. Experts highlight how these cells may affect health, pregnancy, and disease. This study outlines research priorities and challenges in detecting and studying these rare microchimeric cells, aiming to guide future discoveries
Kristine J. Chua, Rachel C. Quilang, Katja Sallinger, Christina Athena Aktipis, Petra Arck, Diana W. Bianchi, Hyun‐Dong Chang, Henderson J. Cleaves II, Michael Eikmans, Heidi E. S. Fjeldstad, David Haig, Whitney E. Harrington, William Horsnell, Daniel P. Jacobsen, Mads Kamper‐Jørgensen, Sami B. Kanaan, Kiarash Khosrotehrani, Nathalie C. Lambert, J. Lee Nelson, Maria B. Olsen, Tiffany D. Pan, Jelmer R. Prins, Frank A. Schildberg, Anne Cathrine Staff, Anders Ståhlberg, Ina A. Stelzer, Christopher Urbschat, Sing Sing Way, Melissa A. Wilson, Jody Ye, Thomas Kroneis, Amy M. Boddy   +31 more
wiley   +1 more source

Fusion de réseaux de contraintes qualitatives définis sur différents formalismes qualitatifs

, 2009
National audienceDans cet article nous nous intéressons au problème de la fusion de réseaux de contraintes qualitatives (RCQ) définis sur différents formalismes qualitatifs.
Condotta, Jean-Francois, Kaci, Souhila, Schwind, Nicolas, Marquis, Pierre   +3 more
core   +2 more sources

Equity in diagnosis through adequate clinical trial design in diagnostic performance studies

Alzheimer's &Dementia, Volume 21, Issue S2, December 2025.
Abstract Background Access to healthcare is unbalanced across different populations with disparities in the availability of diagnostic tests. Additionally, test development currently relies on studies with limited representation of minorities and comorbidities present in the real clinical population.
Imke Kirste, David Caley, Clara Quijano Rubio, Margherita Carboni   +3 more
wiley   +1 more source