Results 91 to 100 of about 31,026 (271)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Investigation of Workload Control Methods for Shops with Re-Entrant Flows

Management Systems in Production Engineering
The re-entrant flow with an unpredictable nature of arrival would apparently harm production plans and schedules in flow type of shops. The re-entrant flow with varied arrival frequencies in rotor blade manufacturing is quite complicated and results in ...
Prabhu Aruna, Raghunandana K, Yogesh Pai P, Barboza Augustine B.V.   +3 more
doaj   +1 more source

Optimization of an Air Filled Compact Re-Entrant Coaxial Resonator for a C-Band Bandpass Filter

IEEE Access, 2018
This paper proposes an enhanced model for a re-entrant coaxial resonator and analyzes the capacitance behavior between its different sections and the Q-factor, for which mathematical expressions are derived.
Christophe Hallet, Jean-Francois Favennec, Eric Rius, Jessica Benedicto, Ludovic Carpentier, Damien Pacaud   +5 more
doaj   +1 more source

Modeling and Analysis of Re-entrant Production Systems [PDF]

, 2006
This paper presents a model and analysis of a re-entrant production line with finite buffers and unreliable machines. Semiconductor device and liquid crystal display (LCD) fabrication processes are characterized as a re-entrant process, in which a ...
Gershwin, Stanley B., Jang, Young Jae
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Atrial Tachycardia in the Coronary Sinus Communicating With Circumflex Artery Aneurysm

JACC: Case Reports
Coronary artery fistula is a rare anomaly, and localized re-entrant atrial tachycardia (AT) in the coronary sinus (CS) has rarely been reported. We report a case in a patient with a left circumflex artery aneurysm associated with the CS fistula who ...
Mitsuaki Itoh, MD, PhD, Akira Shimane, MD, Tomofumi Takaya, MD, PhD, Hiroya Kawai, MD, PhD   +3 more
doaj   +1 more source

Partial cavity instabilities [PDF]

, 1998
This paper reviews some of the literature on partial cavity instabilities on single hydrofoils and then summarizes the striking differences in the appearance and behavior of partial cavities on swept foils (as opposed to two-dimensional, unswept foils ...
Brennen, C. E., Duttweiler, M. E.
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

STUDY ON TENSILE MECHANICAL BEHAVIOR OF X-TYPE RE-ENTRANT HONEYCOMB STRUCTURE

Jixie qiangdu, 2020
Based on the re-entrant mechanism,the microstructure of the star and the re-entrant hexagon is combined. This paper designs a new re-entrant honeycomb structure model（X-shaped structure）.
WANG Liang, LIU HaiTao
doaj