Results 141 to 150 of about 7,803,272 (294)
Advanced Science, EarlyView.A bioactive self‐delivering SNAP‐TAC platform responds to tumor‐associated cathepsin B and glutathione, enabling in situ bioorthogonal synthesis of a BRD4‐degrading proteolysis‐targeting chimera within the tumor microenvironment. The resulting BRD4 degradation and PD‐L1 downregulation synergize with photodynamic therapy‐induced immunogenic cell death ...
Shiqin Jian +14 more
wiley +1 more source
, 2015 The paper presents a new bottom-up integrated approach combining hydrogeochemistry and social sciences for tackling groundwater issues in rural areas. Under the need to assess anthropogenic impacts due to combined agricultural and domestic pollution, the
Re Viviana, RE, Viviana
core
cis‐Carboxylate Enhancement of Mn(III)‐OH Hydrogen Atom Abstraction through PCET Thermodynamics
Advanced Science, EarlyView.ABSTRACT Manganese(III)‐hydroxo intermediates are proposed as key hydrogen atom abstraction (HAA) species in manganese‐dependent enzymes, yet how first‐sphere carboxylate ligands control their proton‐coupled electron transfer (PCET) thermodynamics remains poorly understood.
Yuri Lee +4 more
wiley +1 more source
Data from the GCA article "Highly siderophile element and Re-Os isotope systematics of a Neoproterozoic Iron Formation and its temporal relation to glaciation events"THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST
Schulz, Toni +1 more
core +1 more source
Advanced Science, EarlyView.Osmium nanoparticles anchored on CoFe layered double hydroxide (Os/CoFe LDH) stabilize high‐valent Co/Fe species and modulate the interfacial water configuration via surface engineering. This work presents a facile surface engineering strategy for constructing efficient and durable OER electrocatalysts for alkaline seawater, and expands the ...
Xindong She +8 more
wiley +1 more source
Advanced Science, EarlyView.Biophysical studies of Doc2B yield a cryo‐electron microscopy structure of its complex with the synaptic vesicle priming factor Munc13‐1 and its binding site to the SNARE complex that mediates synaptic vesicle fusion. These and other results suggest a novel model whereby Doc2 proteins regulate neurotransmitter release through sequential interactions ...
Cyrus T. Rastegar +8 more
wiley +1 more source
Overcoming Out‐of‐Plane Conduction by Changing Nanosheet Morphology
Advanced Science, EarlyView.HTaWO6 membrane made of stacked nanotubes exhibits high out‐of‐plane proton conductivity of 1.7 mS/cm. High current density (1.26 A cm−2) and power density (294 mW cm−2) indicate the potential as a fuel‐cell electrolyte. The morphology‐driven strategy establishes topology engineering as a new design principle for efficient ion transport in two ...
Yuichi Sakuda +7 more
wiley +1 more source
Advanced Science, EarlyView.USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian +9 more
wiley +1 more source
Rhizodeposition Drives One Third of Belowground Carbon Input in Agroecosystems
Advanced Science, EarlyView.This study quantifies photosynthesized C allocation in the plant–soil system across six crop types: barley, wheat, maize, rice, legumes and grasses. It reports C partitioning into shoot respiration, shoot‐C, root‐C, net rhizodeposition and root‐derived CO2, providing standardized percentage averages and GPP‐derived absolute values as a robust baseline ...
Zhengjun Yan +10 more
wiley +1 more source
Ages from Re-Os isotopes in peridotites
International Kimberlite Conference Extended Abstracts: 2008, 2019 openaire +2 more sources