Results 151 to 160 of about 53,167 (298)

The Enhanced Whey Protein Oral Bioavailability and Muscle Anabolism Ability by a Simple and Effective Piperine‐Whey Protein Synergistic Codelivery System

open access: yesAdvanced Science, EarlyView.
WP(Pip) is a mixture of whey protein and piperine‐loaded nanoemulsion stabilized by WP through microfluidic homogenization. Acting as a “smart key,” piperine opens epithelial tight junctions to enhance absorption of whey protein and, thereby increasing circulating amino acid availability, synergistically up‐regulates the mTOR signaling pathway in ...
Qing Yue   +10 more
wiley   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu   +10 more
wiley   +1 more source

Detachment‐Induced FAK‐STAT3‐NNMT Inhibits CTCs Anoikis to Promote Breast Cancer Metastasis by Enhancing Fatty Acid Oxidation

open access: yesAdvanced Science, EarlyView.
The FAK‐STAT3‐NNMT axis drives anoikis resistance in circulating tumor cells by reprogramming fatty acid oxidation. Targeting this metabolic vulnerability suppresses metastasis, untangling a key mechanism of breast cancer progression and revealing NNMT as a promising therapeutic target.
Qingchao Tong   +13 more
wiley   +1 more source

Enhanced erosion by continental arc volcanism as a driver of the Cambrian Explosion. [PDF]

open access: yesNat Commun
Wu Y   +12 more
europepmc   +1 more source

Ages from Re-Os isotopes in peridotites

open access: yesInternational Kimberlite Conference Extended Abstracts: 2008, 2019
openaire   +2 more sources

Glucuronolactone Promotes Mucin Sulfation to Alleviate Deoxynivalenol‐Induced Intestinal Injury via Microbiota‐Dependent and ‐Independent AHR Activation

open access: yesAdvanced Science, EarlyView.
Glucuronolactone (GLU) as a natural metabolite of glucose, increases Lactobacillus amylovorus abundance and luminal IAA level to activate AHR signaling. In addition, GLU itself can directly elevate AHR signaling activity independently of microbiota and IAA.
Chenbin Cui   +8 more
wiley   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo   +9 more
wiley   +1 more source

Evaluating the Use and Feasibility of Indocyanine Green (ICG) as a Beacon of Precision in Sentinel Node Biopsy for Breast Cancer from an Oncoplastic Practice in India. [PDF]

open access: yesCancers (Basel)
Koppiker CB   +13 more
europepmc   +1 more source

Photonuclear Population of 229m,gTh in Th‐Doped Crystals Toward Nuclear Clock Development

open access: yesAdvanced Science, EarlyView.
This study demonstrates a novel photonuclear approach for producing the nuclear clock isomer 229mTh in thorium‐doped crystals, overcoming current supply limitations. Through cross‐section calculations and Monte Carlo simulations, we identify optimal crystal materials and irradiation conditions, achieving high signal‐to‐noise ratios.
Hao‐Yang Lan   +9 more
wiley   +1 more source

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