Results 71 to 80 of about 1,126 (270)

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

Advanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu, Simin Bi, Zhechen Liu, Xiaofeng Zhou, Hengwei Qin, Nicola Dalbeth, Minbiao Ji, Yinghui Hua   +7 more
wiley   +1 more source

Selection and Treatment of Data for Radiocarbon Calibration: An Update to the International Calibration (IntCal) Criteria [PDF]

, 2013
High-quality data from appropriate archives are needed for the continuing improvement of radiocarbon calibration curves. We discuss here the basic assumptions behind 14C dating that necessitate calibration and the relative strengths and weaknesses of ...
Beck, J. Warren,, Grootes, Pieter, Reimer, Ron W.,, Blackwell, Paul G, Richards, David A, Richards, David, Manning, Sturt W., Bronk-Ramsey, Christopher, Hogg, Alan G.,, Hughen, Konrad, Richards, David A.,, Haflidason, Haflidi,, Blackwell, Paul, Scott, E. M., Beck, J Warren, Buck, C.E., Hogg, Alan G, Turney, Chris S.M., Beck, J.W., Bard, Edouard, van der Plicht, Johannes, Bard, E., Heaton, Timothy J., Kromer, Bernd, Hatté, Christine,, Manning, Sturt W.,, Hughen, Konrad A, Turney, Christian S M, Kaiser, K.F., Reimer, Paula J., Richards, David A., Van Der Plicht, J., Southon, John, Blackwell, P.G., Buck, Caitlin E., Plicht, Johannes van der,, Brown, David M., Guilderson, Thomas, P., Bronk Ramsey, C, Hughen, Konrad A., Scott, E Marian, Blackwell, Paul G., Ramsey, Christopher Bronk, Friedrich, Michael,, Blackwell, Paul G.,, Hogg, Alan G., Bayliss, Alex,, Turney, Christian, Reimer, Paula J.,, Brown, David M, Grootes, Pieter M.,, Kaiser, K. Felix, Hogg, A.G., Reimer, Paula; id_orcid, Hughen, Konrad A.,, Edwards, R. Lawrence, Guilderson, Thomas P.,, Reimer, PJ, Turney, C.S.M., Southon, John R.,, Grootes, Pieter M, Manning, Sturt W, Grootes, P.M., Hajdas, Irka,, Kaiser, K. Felix,, Reimer, Ron, Heaton, Timothy J.,, Grootes, Pieter M., Brown, David M.,, Haflidason, Haflidi, Edwards, R. Lawrence,, Southon, J.R., Southon, John R., Guilderson, Thomas P., Bard, Eduoard, Brown, David, Bayliss, A., Edwards, R Lawrence, Hogg, Alan, Heaton, T.J., Edwards, R.L., Southon, John R, Bard, Edouard,, Reimer, Ron W., Turney, Christian S.M.,, Bronk Ramsey, Christopher,, Manning, Sturt, Bayliss, Alex, Guilderson, Thomas, Heaton, Timothy, Reimer, Paula, Buck, Caitlin E.,, Friedrich, M., Hajdas, I., Buck, Caitlin, Reimer, Ron W, Friedrich, Michael, Kromer, Bernd,, Turney, Christian S. M., Guilderson, T.P., Hajdas, Irka, Scott, E. Marian,, Hatté, Christine, Kaiser, K Felix, Manning, S.W., Buck, Caitlin E, Richards, D.A., Scott, Marian E., Beck, J. Warren, Scott, E. Marian, Bronk Ramsey, Christopher, Heaton, Timothy J, Guilderson, Thomas P   +112 more
core   +1 more source

Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
Depression is increasingly recognized as a risk factor for chronic diseases, yet its biological impact on cancer remains unclear. Using data from more than 490 000 participants across three international cohorts, we show that depression significantly increases the risk of liver cancer.
Ruijiang Zeng, Mengmeng Wang, Kang Wang, Zhuo Xing, Yulong Hong, Tongtong Li, Geng Zong, Chong Yang, Dan Zhang, Zhangling Chen, Xin Jin   +10 more
wiley   +1 more source

Application of Re-Os Geochronolgy to Offshore California Basins [PDF]

, 2020
The rhenium-osmium (Re-Os) isotope system has historically been used with geochronological applications in the dating of igneous and metamorphic rocks, and in constraining the Earth’s geochemical evolution.
Silva, Leiser Guillermo 1992-
core  

Age and Source of the Jinjingzui Skarn-Type Gold Deposit in the Southeastern Hubei Province, China

Applied Sciences
The Jinjingzui gold (Au) deposit is located in the central part of Edong, China. The theoretical gold reserves are large with significant potential for mining and future development.
Yan Li, Chun Cheng, Yuan Yao, Qinghua Yan   +3 more
doaj   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Exclusive Hydroformylation of Terminal Olefins: A Phosphorus‐Free Ruthenium System for the Selective Functionalization of Complex Mixtures

Angewandte Chemie, EarlyView.
Development of a phosphorus‐free Ru/DBU catalyst enabling highly chemo‐ and regioselective hydroformylation of terminal olefins, sparing internal double bonds. Optimization of reaction parameters, ligand effects, and substrate scope including industrial feedstocks was realized.
Mohamed Niyaz Vellala Syed Ali, Ida Ziccarelli, Dilver Peña Fuentes, Christoph Kubis, Robert Franke, Ralf Jackstell, Matthias Beller   +6 more
wiley   +2 more sources

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

Tailoring High‐Valent Iron‐Oxo Species Redox via Extended π‐Fe3d–O2p Orbital Overlapping Toward Chemical‐Efficient Water Purification

Angewandte Chemie, EarlyView.
We address the long‐standing challenge of reactivity–selectivity trade‐off by precisely tuning the redox properties of Fe(IV), rather than simply accelerating its formation, to enable chemically efficient and low‐emission water treatment. ABSTRACT High‐valent iron oxo species (Fe(IV)) are attractive for wastewater treatment because of their high ...
Hongyu Zhou, Junwen Chen, Jiuyi Wang, Xinhao Wang, Qiming Zhang, Shiying Ren, Xuning Li, Li Gao, Shaobin Wang, Xiaoguang Duan   +9 more
wiley   +2 more sources

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source