Results 91 to 100 of about 133,963 (328)

Use systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans

open access: yesFrontiers in Pharmacology, 2014
In the kidney, glucose in glomerular filtrate is reabsorbed primarily by sodium-glucose cotransporters 1 (SGLT1) and 2 (SGLT2) along the proximal tubules.
Yasong eLu   +3 more
doaj   +1 more source

Reabsorption

open access: yes
Citation: 'reabsorption' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.16021 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +2 more sources

Glucose Reabsorption in Experimental Glomerulonephritis

open access: yesExperimental Biology and Medicine, 1977
SummaryThe relationship between glo-merular filtration rate and tubular glucose reabsorption was examined in rats with experimental glomerulonephritis. Glomerular filtration rates (single kidney) varied from 0.09 to 0.95 ml/min and superficial nephron filtration rates ranged from 4.4 to 38.2 nl/ min. A direct linear relationship between filtration rate
J, Kawamura, D C, Mazumdar, H, Lubowitz
openaire   +2 more sources

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

open access: yesAdvanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park   +23 more
wiley   +1 more source

Reactive Oxygen Species Modulation of Na/K-ATPase Regulates Fibrosis and Renal Proximal Tubular Sodium Handling

open access: yesInternational Journal of Nephrology, 2012
The Na/K-ATPase is the primary force regulating renal sodium handling and plays a key role in both ion homeostasis and blood pressure regulation. Recently, cardiotonic steroids (CTS)-mediated Na/K-ATPase signaling has been shown to regulate fibrosis ...
Jiang Liu   +3 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Dental Reabsorptions

open access: yes, 2021
Dental reabsorptions can be classified as being caused by trauma, infection, or by a hyperplastic invasive, often idiopathic process. Objectives: The aim of this paper is to classify all types of dental reabsorptions based on their etiology. It will describe their pathogenesis, histologic manifestations, risk factors, and clinical or radiological ...
openaire   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

open access: yesAdvanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones   +14 more
wiley   +1 more source

Analysis of efficacy of SGLT2 inhibitors using semi-mechanistic model

open access: yesFrontiers in Pharmacology, 2014
Renal sodium-dependent glucose co-transporter 2 (SGLT2) is one of the most promising targets for the treatment of type 2 diabetes. Two SGLT2 inhibitors, dapagliflozin and canagliflozin, have already been approved for use in USA and Europe; several ...
Oleg eDemin Jr   +3 more
doaj   +1 more source

Increased Glomerular Hydrostatic Pressure is Associated with Tubular Creatinine Reabsorption in Healthy Subjects

open access: yesKidney & Blood Pressure Research, 2020
Background: Cr is secreted by the proximal tubules and thus Cr clearance (Ccr) can overestimate inulin clearance (Cin). However, in some cases, Ccr can even underestimate Cin. This suggests that Cr could be reabsorbed in the tubuli.
Akihiro Tsuda   +7 more
doaj   +1 more source

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