Results 151 to 160 of about 7,822,367 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Deficits in Forelimb Reach Learning in a Mouse Model of Fragile X Syndrome. [PDF]

eNeuro
Young LF, Derham A, Zhu R, Suvrathan A.
europepmc   +1 more source

Do microfinance institutions reach the poorest? [PDF]

The question raised in the title is an important one to the microfinance sector, especially since the Microcredit Summit held in Washington, DC, in 1997.
Henry, Carla, Lapenu, Cécile, Sharma, Manohar, Zeller, Manfred   +3 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Somatosensory input drives membrane potential dynamics in motor cortex during voluntary limb movement. [PDF]

PLoS Biol
Voigt BC, Rau F, Estebanez L, Poulet JFA.   +3 more
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Response of sediment delivery ratio to water-sediment and riverbed boundary conditions during flood events in the lower yellow river since 2000. [PDF]

Sci Rep
Zhang X, Zhang M, Zhang C, Zhang X, Sun Z.   +4 more
europepmc   +1 more source

The German Constitution of July 31, 1919. [PDF]

, 1921
Reach, Emil
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Modified Star Excursion Balance Test Performance in Individuals With Chronic Ankle Instability: A Participant-Level Analysis. [PDF]

J Foot Ankle Res
Forsyth L, Simpson J, Pourkazemi F, Torp DM, Burcal C, Koldenhoven RM, Donovan L, Jaffri A, Al Adal S, Mitchell A, Childs CR.   +10 more
europepmc   +1 more source