Complementary role of humanitarian civil society organisations in bridging gaps in immunisation programming in conflict and crisis-affected settings: the REACH Project experience. [PDF]
Olorunsaiye CZ +7 more
europepmc +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Comparison of measured and modeled data for carcinogen workplace exposure assessment: a case study on chromium trioxide under REACH and OSH frameworks. [PDF]
Zellino C +14 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
'Hard-to-Reach' or 'Hardly Reached'? Underservice, Marginalisation and Inequity in Care. [PDF]
Jackson D, Bond C, Watson A, Cleary M.
europepmc +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Characteristics of Human-Like Virtual Profiles in Relation to Audience Reach and Engagement on Instagram: Secondary Data Analysis. [PDF]
Lebrecht AM +3 more
europepmc +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Using Instagram for public education in trauma prevention: experience of an academic Trauma League. [PDF]
Dos Santos HAF +5 more
europepmc +1 more source

