Results 91 to 100 of about 443,134 (353)

On analysis of chemical reactions coupled gas flows in SOFCs [PDF]

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009)   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Pulsating Front Speed-up and Quenching of Reaction by Fast Advection

open access: yes, 2007
We consider reaction-diffusion equations with combustion-type non-linearities in two dimensions and study speed-up of their pulsating fronts by general periodic incompressible flows with a cellular structure.
Andrej Zlatoš   +13 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

High speed turbulent reacting flows: DNS and LES [PDF]

open access: yes
Work on understanding the mechanisms of mixing and reaction in high speed turbulent reacting flows was continued. Efforts, in particular, were concentrated on taking advantage of modern computational methods to simulate high speed turbulent flows.
Givi, Peyman
core   +1 more source

Kinetic modeling of detonation and effects of negative temperature coefficient

open access: yes, 2016
The kinetic modeling and simulation of reactive flows, especially for those with detonation, are further investigated. From the theoretical side, a new set of hydrodynamic equations are deduced, where the viscous stress tensor and heat flux are replaced ...
Lin, Chuandong   +4 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Current Economic and Financial Crisis – New Issues or Returning to the Old Problems? Paradigms, Causes, Effects and Solutions Adopted [PDF]

open access: yesTheoretical and Applied Economics, 2011
At the ideological level, the current crisis, as the others in history, has triggered an intellectual debate among several applicable ideas: ultra-liberal theory of the "invisible hand" of Adam Smith, Keynes's theory of state interventionism and even neo-
Felix TOTIR, Ingrid-Mihaela DRAGOTĂ
doaj   +1 more source

Numerical Study on Regenerative Cooling Characteristics of Kerosene Scramjets

open access: yesInternational Journal of Aerospace Engineering, 2020
The use of kerosene-based regenerative cooling for scramjet has been found widespread attention due to its inherent nature of high energy utilization efficiency and good thermal protection performance. In order to provide a reference for the later design
Xuan Jin, Chibing Shen, Xianyu Wu
doaj   +1 more source

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