Results 101 to 110 of about 443,894 (309)

Light Element Synthesis in High Entropy Relativistic Flows Associated with Gamma Ray Bursts

open access: yes, 2002
We calculate and discuss the light element freeze-out nucleosynthesis in high entropy winds and fireballs for broad ranges of entropy-per-baryon, dynamic timescales characterizing relativistic expansion, and neutron-to-proton ratios.
George M. Fuller   +4 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Universality in active chaos

open access: yes, 2004
Many examples of chemical and biological processes take place in large-scale environmental flows. Such flows generate filamental patterns which are often fractal due to the presence of chaos in the underlying advection dynamics.
Adilson E. Motter   +5 more
core   +1 more source

Phenomenological characterization and effect of reaction rate of coaxial reaction flow

open access: yes河南理工大学学报. 自然科学版
ObjectivesFor precise control of the coaxial reaction flow process, the macroscopic phenomenological characterization method and control law of reaction rate,Methodsthe cross-linking process of calcium alginate hydrogel hollow fiber was observed online by tracing Ca2+ with murexide indicator.
LI Yu   +5 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Laminar-Turbulent Patterning in Transitional Flows

open access: yes, 2017
Wall-bounded flows experience a transition to turbulence characterized by the coexistence of laminar and turbulent domains in some range of Reynolds number R, the natural control parameter.
Manneville, Paul
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Current Economic and Financial Crisis – New Issues or Returning to the Old Problems? Paradigms, Causes, Effects and Solutions Adopted [PDF]

open access: yesTheoretical and Applied Economics, 2011
At the ideological level, the current crisis, as the others in history, has triggered an intellectual debate among several applicable ideas: ultra-liberal theory of the "invisible hand" of Adam Smith, Keynes's theory of state interventionism and even neo-
Felix TOTIR, Ingrid-Mihaela DRAGOTĂ
doaj   +1 more source

Boundary layer integral matrix procedure: Verification of models [PDF]

open access: yes
The three turbulent models currently available in the JANNAF version of the Aerotherm Boundary Layer Integral Matrix Procedure (BLIMP-J) code were studied.
Bonnett, W. S., Evans, R. M.
core   +1 more source

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