Results 91 to 100 of about 443,894 (309)

Analysis of non-premixed turbulent reacting flows [PDF]

Studies of chemical reactions occurring in turbulent flows are important in the understanding of combustion and other applications. Current numerical methods are limited in their applications due to the numerical resolution required to completely capture
Hill, James C., Leonard, Andy D.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Numerical Investigation of Hydrogen Production via Methane Steam Reforming in Tubular Packed Bed Reactors Integrated with Annular Metal Foam Gas Channels

Energies
Methane steam reforming is the most widely adopted hydrogen production technology. To address the challenges associated with the large radial thermal resistance and low mass transfer rates inherent in the tubular packed bed reactors during the MSR ...
Yifan Han, Zihui Zhang, Zhen Wang, Guanmin Zhang   +3 more
doaj   +1 more source

Switching Dynamics in Reaction Networks Induced by Molecular Discreteness [PDF]

, 2006
To study the fluctuations and dynamics in chemical reaction processes, stochastic differential equations based on the rate equation involving chemical concentrations are often adopted. When the number of molecules is very small, however, the discreteness
Gibson M A, Horsthemke W, Kunihiko Kaneko, Nicolis G, Olsson N, Thul R, van Kampen N G, Yuichi Togashi   +7 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Collective flows of light particles in the Au+Au collision at intermediate energies

, 2014
The Skyrme potential energy density functional is introduced into the Ultrarelativistic Quantum Molecular Dynamics (UrQMD) model and the updated version is applied to studying the directed and elliptic flows of light particles (protons, neutrons ...
Guo, Chenchen, Li, Qingfeng, Li, Zhuxia, Trautmann, W., Wang, Yongjia, Zhang, Hongfei   +5 more
core   +1 more source

Effects of heat release on triple flames [PDF]

, 1995
Heat release effects on laminar flame propagation in partially premixed flows are studied. Data for analysis are obtained from direct numerical simulations of a laminar mixing layer with a uniformly approaching velocity field.
Liñán Martínez, Amable, Ruetsch, G., Vervisch, L.   +2 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Mass Transfer and MHD Free Convection Flow Across a Stretching Sheet with a Heat Source and Chemical Reaction

East European Journal of Physics
This work examines mass transfer and MHD free convective flow across a stretching sheet in the presence of a heat source and a chemical reaction. The sheet's stretching action propels the flow, while a magnetic field applied perpendicular to the flow ...
Sunmoni Mudoi, Satyabhushan Roy, Dipak Sarma, Ankur Kumar Sarma   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source