Results 121 to 130 of about 37,264 (315)
Capital Flows and Money Supply: The Degree of Sterilisation in Pakistan [PDF]
Under the current managed float exchange rate system; the central bank may respond to an exchange market disequilibria by changing either the international reserves or the exchange rates.
Abdul Qayyum, Muhammad Arshad Khan
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Chemical reaction effect on MHD free convection flow in a micropo
Alexandria Engineering Journal, 2016 The present study analyses the chemical reaction effect on a boundary layer flow of an electrically conducting micropolar fluid subject to transverse magnetic field along a vertical plate with variable wall temperature and concentration. The governing nonlinear partial differential equations are transformed into a system of coupled nonlinear ordinary ...
P.K. Rout +3 more
openaire +1 more source
Consumer reaction on tumbling funds - Evidence from retail fund outflows during the financial crisis 2007/2008 [PDF]
Contrary to the findings reported in some of the extant literature, our study indicates that over the past few years a change in investors’ behavior patterns means that investment decisions are made at short notice, and that shares are redeemed in a ...
Daniel Schmidt, Frank Schmielewski
core
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
The Unholy Trinity of Financial Contagion [PDF]
Over the last 20 years, some financial events, such as devaluations or defaults, have triggered an immediate adverse chain reaction in other countries -- which we call fast and furious contagion.
Carmen Reinhart +2 more
core +2 more sources
Rarefied Reactive Gas Flows over Simple and Complex Geometries Using an Open-Source DSMC Solver
AerospaceDuring atmospheric reentry, a significant number of chemical reactions are produced inside the high-temperature shock wave formed upstream of the spacecraft.
Rodrigo Cassineli Palharini +2 more
doaj +1 more source
Why Do Institutional Plan Sponsors Hire and Fire their Investment Managers? [PDF]
This paper examines the investment allocation decisions of pension plans, endowments, foundations, and other institutional plan sponsors. The experience and education of plan sponsors and the environment (both regulatory and agency) of the institutional ...
Christopher Knittel +3 more
core