Results 71 to 80 of about 12,566,865 (365)

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Reaction mechanism of formate dehydrogenase studied by computational methods

JBIC Journal of Biological Inorganic Chemistry, 2018
Formate dehydrogenases (FDHs) are metalloenzymes that catalyse the reversible conversion of formate to carbon dioxide. Since such a process may be used to combat the greenhouse effect, FDHs have been extensively studied by experimental and theoretical ...
G. Dong, U. Ryde
semanticscholar   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Reaction mechanism of SiC-TiSi₂ by melt infiltration method

Cailiao gongcheng, 2019
The melt infiltration method is one of the main preparation method of SiC matrix composites. Complex reactions and multi-component diffusion are involved in molten-Si infiltration of a C-based preform.
ZHOU Yi-ran, LIU Hu, YANG Jin-hua, JIANG Zhuo-yu, LYU Xiao-xu, JIAO Jian   +5 more
doaj   +1 more source

Hydration mechanism of heterogeneous alkaline deacetylation of chitin [PDF]

Vestnik MGTU, 2017
In the work the hypothesis has been proposed explaining the features of the kinetics of chitin/chitosan alkali deacetylation reaction in highly concentrated solutions of sodium hydroxide, which almost completely stops after 30–60 min after the start of ...
Novikov V. Yu., Konovalova I. N. , Kuchina Yu. A. , Dolgopyatova N. V. , Cherkun Yu. A.   +4 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Perspective—A New Viewpoint on the Mechanism of the Hydrogen Evolution Reaction on Various Transition Metal Electrodes

ECS Advances
In the research for the catalytic activity of metals, the electronegativity (EN) and valence electronic configuration (VEC) of the atoms of metals have been considered as important factors.
Youyi Sun
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Photo-catalytic selective organic transformations by Fe-doped octahedral molecular sieves (manganese oxide) nano-structure

Journal of Asian Ceramic Societies, 2018
The future development of chemistry entails environment-friendly and energy-sustainable alternatives for organic transformations. Visible light photo-catalysis can address these challenges. Octahedral molecular sieve manganese oxide (cryptomelane, OMS-2)
S. Said, Heba H. El Maghrabi, M. Riad, S. Mikhail   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source