Results 81 to 90 of about 14,626,809 (402)

A REP-FAMSEC Method as a Tool in Explaining Reaction Mechanisms: A Nucleophilic Substitution of 2-Phenylquinoxaline as a DFT Case Study [PDF]

, 2021
Brian Kamogelo Mdhluli, Winston Nxumalo, Ignacy Cukrowski   +2 more
openalex   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Isotopic Scaling in Nuclear Reactions

, 2000
A three parameter scaling relationship between isotopic distributions for elements with Z$\leq 8$ has been observed that allows a simple description of the dependence of such distributions on the overall isospin of the system.
A. Majumder, A. S. Botvina, Aage Bohr, B. A. Li, Bao-An Li, C. K. Gelbke, C. K. Gelbke, G. J. Kunde, G. Verde, H. S. Xu, H. S. Xu, I. Bombaci, J. Brzychczyk, J. Randrup, J. Tõke, M. B. Tsang, M. D’Agostino, R. Laforest, R. Wada, S. Albergo, S. R. Souza, Scott Pratt, V. E. Viola, V. V. Volkov, V. Weisskopf, W. A. Friedman, W. A. Friedman, W. A. Friedman, W. Friedman, W. G. Lynch, W. U. Schroeder   +30 more
core   +1 more source

Synthetically Diversified Protein Nanopores: Resolving Click Reaction Mechanisms.

ACS Nano, 2019
Nanopores are emerging as a powerful tool for the investigation of nanoscale processes at the single-molecule level. Here, we demonstrate the methionine-selective synthetic diversification of α-hemolysin (α-HL) protein nanopores and their exploitation as
M. M. Haugland, S. Borsley, Dominic F. Cairns-Gibson, Alex Elmi, S. Cockroft   +4 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Research progress on removing typical organic heavy metal complexes from water by adsorption

Gongye shui chuli
The efficient removal of low concentration, recalcitrant, and highly toxic organic heavy metal complexes in industrial wastewater is a hot issue in the field of heavy metal pollution control.
ZHANG Wei, LUO Xubiao, OUYANG Ting, LIU Zhengwei, XIONG Ping   +4 more
doaj   +1 more source

Micropollutant Oxidation Studied by Quantum Chemical Computations: Methodology and Applications to Thermodynamics, Kinetics, and Reaction Mechanisms.

Accounts of Chemical Research, 2019
The abatement of organic micropollutants during oxidation processes has become an emerging issue for various urban water systems such as drinking water, wastewater, and water reuse.
P. Tentscher, Minju Lee, U. von Gunten
semanticscholar   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

A Brief Overview of TiO2 Photocatalyst for Organic Dye Remediation: Case Study of Reaction Mechanisms Involved in Ce-TiO2 Photocatalysts System

Journal of nanomaterials, 2018
The ever-increasing world population and the rapid growth of industrialization globally make necessary the development of clean technologies and affordable materials for remediating environmental pollution from petroleum-based hydrocarbons and dyes ...
M. Pawar, S. Topcu Sendogdular, P. Gouma
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source