Results 111 to 120 of about 352,512 (360)
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Research and Reports in Tropical Medicine, 2021 Zubair Shahid,1 Nadia Karim,1 Fakhar Shahid,2 Zohaib Yousaf1,3 1Internal Medicine, Hamad Medical Corporation, Doha, Qatar; 2General Surgery, Hamad Medical Corporation, Doha, Qatar; 3Dresden International University, Dresden, GermanyCorrespondence: Zubair
Shahid Z, Karim N, Shahid F, Yousaf Z
doaj
Post-natalizumab disease reactivation in multiple sclerosis: systematic review and meta-analysis
Therapeutic Advances in Neurological Disorders, 2019 Background: Natalizumab (NTZ) is sometimes discontinued in patients with multiple sclerosis, mainly due to concerns about the risk of progressive multifocal leukoencephalopathy.
L. Prosperini +4 more
semanticscholar +1 more source
Predictive modeling of reactivation rates.
, 2013 (A) Shown is the correlation between the measured reactivation (x-axis) and the predicted reactivation (trained outputs) (y-axis) using 588 out of 600 total input-output points (see methods section - Neural network model).
Fuqu Yu (273687) +7 more
core +1 more source
Autobiographical Memory Reactivation and Cognitive Restructuring
, 2022 A number of studies have investigated strategies to interfere with the reconsolidation of episodic memories by pairing episodic memory reactivation with learning new information (e.g., Scully et al., 2017; Speer et al., 2021).
Xandra Kredlow
core +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
Sleep spindle refractoriness segregates periods of memory reactivation
bioRxiv, 2017 The stability of long-term memories is enhanced by reactivation during sleep. Correlative evidence has linked memory reactivation with thalamocortical sleep spindles, although their functional role is poorly understood.
J. Antony +5 more
semanticscholar +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Hepatitis C Virus and Hepatitis B Virus Co-Infection
Viruses, 2020 Hepatitis C virus (HCV) and hepatitis B virus (HBV) co-infection can be encountered in either virus endemic countries. Co-infection can also be found in populations at risk of parenteral transmission.
Yi-Fen Shih, Chun-Jen Liu
doaj +1 more source
A Sleeping Giant: Late HBV Reactivation After Rituximab-Based Chemotherapy Despite Correct Prophylaxis [PDF]
Anna A Nowicka,1– 3 Anna Szymanek-Pasternak,1,2 Justyna Janocha-Litwin,1,2,4 Krzysztof Simon1,2 1Clinical Department of Infectious Diseases and Hepatology, Wroclaw Medical University, Wroclaw, Poland; 2First Department of Infectious Diseases, J ...
Janocha-Litwin J +3 more
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