Results 121 to 130 of about 203,884 (312)

Diapause development in Aquarius paludum (Heteroptera: Gerridae)

open access: yesEuropean Journal of Entomology, 2004
Diapause fixation and development were studied in females of a Czech population of Aquarius paludum by monitoring changes in oxygen uptake, weight and reproduction potential in field adults between August and February.
Tetsuo HARADA   +3 more
doaj   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

open access: yesAdvanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li   +9 more
wiley   +1 more source

Unraveling tuberculosis patient cluster transmission chains: integrating WGS-based network with clinical and epidemiological insights

open access: yesFrontiers in Public Health
BackgroundTuberculosis remains a global health threat, and the World Health Organization reports a limited reduction in disease incidence rates, including both new and relapse cases.
Darja Sadovska   +13 more
doaj   +1 more source

Stress History Establishes a Transient Tolerant State That Shapes Antibiotic Survival Upon Resuscitation

open access: yesAdvanced Science, EarlyView.
High‐throughput single‐cell analysis of resuscitating bacteria reveals a starvation‐history‐dependent transiently tolerant subpopulation that survives β$\beta$‐lactam exposure by temporarily reducing growth. Distinct from classical persisters, these actively growing yet dynamically modulated cells dominate survival across clinically relevant antibiotic
Kieran Abbott   +5 more
wiley   +1 more source

Late reactivation of thyroid orbitopathy [PDF]

open access: yes, 2004
BackgroundThyroid orbitopathy is characterized by spontaneous remissions and exacerbations. Although data on the natural history are scarce, the active phase is usually self-limited, encompassing an average period of 18-36 months.
King, G., Selva-Nayagam, D., Chen, C.
core   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen   +18 more
wiley   +1 more source

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

open access: yesAdvanced Science, EarlyView.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth   +10 more
wiley   +1 more source

Utilization of Used Bleaching Clay in Pellet Fuel Production with Torrefied Oil Palm Fronds

open access: yesBioResources, 2023
Torrefaction oil palm fronds was studied as a renewable biomass resource for efficient and sustainable pellet fuel production. Employing microwave heating during torrefaction, the process optimized the conditions to enhance the fuel properties. At 300 °C
Pensiri Romyen   +5 more
doaj  

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Timing Customer Reactivation Initiatives [PDF]

open access: yes, 2020
Firms operating in non-contractual settings use customer reactivation initiatives to stimulate inactive customers to resume purchasing. Customer reactivation requires these firms to identify which customers have become inactive at what point in time, and
Wieringa, Jaap E.   +2 more
core  

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