Results 71 to 80 of about 352,512 (360)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Maribavir for Preemptive Treatment of Cytomegalovirus Reactivation.

New England Journal of Medicine, 2019
BACKGROUND Maribavir is a benzimidazole riboside with activity against cytomegalovirus (CMV). The safety and efficacy of maribavir for preemptive treatment of CMV infection in transplant recipients is not known.
J. Maertens, C. Cordonnier, P. Jaksch, X. Poiré, M. Uknis, Jingyang J. Wu, A. Wijatyk, F. Saliba, O. Witzke, S. Villano   +9 more
semanticscholar   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Clinical and epidemiological features of infections caused by HHV-6A and HHV-6B [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To determine the detection rates of HHV-6A and HHV-6B compared to other herpes viruses in children of different age groups. Materials and Methods.
Lysenkova M.Yu., Karazhas N.V., Rybalkina T.N., Veselovsky P.A., Burmistrov E.M., Boshyan R.E., Melekhina E.V., Svitich O.A., Muzyka A.D., Petukhova E.V., Gorelov A.V.   +10 more
doaj  

serologic markers of Epstein-Barr virus reactivation in the conditions of viral encephalitis in young patients

Журнал инфектологии, 2015
The reactivation of Epstein-Barr virus on the background of some basic disease revealed during the development of encephalitis of various etiology could act as a co-factor to trigger the process of demyelinazation of central nervous system tissues ...
O. V. Goleva, E. A. Murina, Z. A. Osipova   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Memory Reactivation during Learning Simultaneously Promotes Dentate Gyrus/CA2,3 Pattern Differentiation and CA1 Memory Integration

Journal of Neuroscience, 2020
Events that overlap with previous experience may trigger reactivation of existing memories. However, such reactivation may have different representational consequences within the hippocampal circuit. Computational theories of hippocampal function suggest
Robert J. Molitor, Katherine R. Sherrill, Neal W. Morton, Alexandra A. Miller, A. Preston   +4 more
semanticscholar   +1 more source

Application and reactivation of magnetic nanoparticles in Microcystis aeruginosa harvesting

, 2015
This study developed a magnetic nanoparticles (MNPs) harvesting and reactivation technique for rapid cyanobacteria Microcystis aeruginosa separation. The harvesting of raw MNPs achieved high efficiency of 99.6% with the MNPs dosage of 0.58g MNPs/g dry ...
Li, Wenyan, Luo, Chunling, Lin, Zhong, Zhen, Zhen, Fu, Yu, Liu, Yueqiao, Zhang, Dayi, Ding, Aizhong, Xu, Yunfeng   +8 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Chagas' Disease and HIV Co-infection: Genotypic Characterization of the Trypanosoma cruzi Strain

Memorias do Instituto Oswaldo Cruz, 1998
In the past few years, new aspects of the immunopathology of Chagas' disease have been described in immunosuppressed patients, such as fatal central nervous system lesions related to the reactivation of the parasite. This article is the first description
Pacheco Raquel S, Ferreira Marcelo S, Machado Maria Inês, Brito Célia MM, Pires Marize Q, Da-Cruz Alda M, Coutinho Sérgio G   +6 more
doaj