Results 111 to 120 of about 26,803 (327)

Review on Abyssomicins: Inhibitors of the Chorismate Pathway and Folate Biosynthesis

Molecules, 2018
Antifolates targeting folate biosynthesis within the shikimate-chorismate-folate metabolic pathway are ideal and selective antimicrobials, since higher eukaryotes lack this pathway and rely on an exogenous source of folate.
Carmen Sadaka, Edmund Ellsworth, Paul Robert Hansen, Richard Ewin, Peter Damborg, Jeffrey L. Watts   +5 more
doaj   +1 more source

Utilising proteomic approaches to understand oncogenic human herpesviruses [PDF]

, 2014
The γ‑herpesviruses Epstein-Barr virus and Kaposi's sarcoma‑associated herpesvirus are successful pathogens, each infecting a large proportion of the human population.
Baquero-Perez, B, Berndt, A, Hughes, DJ, Jackson, BR, Owen, CB, Schumann, S, Whitehouse, A   +6 more
core   +1 more source

Advanced Porous Materials for Maritime Carbon Capture

Advanced Materials, EarlyView.
Carbon capture from emission sources, such as marine vessels, has attracted significant attention over the years. To achieve this goal, sorbents such as metal–organic frameworks (MOFs), porous polymer networks (PPNs), covalent organic frameworks (COFs), and their post‐synthetic modifications are currently being explored.
Kelechi Festus, Ankit Mondal, Jazmine Marquez, Aishi Sikdar, Urme Podder, Qingsheng Wang, Hong‐Cai Zhou   +6 more
wiley   +1 more source

Energy‐Efficient, Sustainable Cascade Glucose Electrooxidation into Glucaric Acid

Advanced Materials, EarlyView.
This study presents a tandem system that efficiently converts glucose into glucaric acid while generating renewable electricity. By decoupling the oxidation process into two cascaded steps, the system achieves an overall 90% Faradaic efficiency and 80% conversion efficiency at ∼0.6 VRHE, significantly reducing energy consumption compared to traditional
Mingming He, Chao Huang, Mingzi Sun, Ruixuan Wang, Yun Song, Jianjun Su, Weihua Guo, Yinger Xin, Qiang Zhang, Yong Liu, Geng Li, Zihao Li, Rui Xue, Bolong Huang, Ben Zhong Tang, Ruquan Ye   +15 more
wiley   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source

Soft Electromagnetic Actuator and Oscillator

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This work presents a groundbreaking soft electromagnetic system capable of bistable actuation and self‐regulated oscillation. Using liquid metal and silicone as a compliant conductor, the actuator enables force generation, sensing, and feedback with minimal power.
Noah D. Kohls, Yi Chen Mazumdar
wiley   +1 more source

Offline hippocampal reactivation during dentate spikes supports flexible memory [PDF]

, 2023
Stephen B. McHugh, Vítor Lopes‐dos‐Santos, Manfredi Castelli, Giuseppe P. Gava, Sophie E. Thompson, Shu K. E. Tam, Katja Hartwich, David Dupret   +7 more
openalex   +1 more source

Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications

Advanced Optical Materials, EarlyView.
This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei, Luping Wang, Haitong Jing, Xian Qin, Jiong‐Wei Wang, Xiaogang Liu   +5 more
wiley   +1 more source

(3Z)-5-Chloro-3-(Hydroxyimino)indolin-2-one attenuates hyperglycemia, increased hepatic glycogen content and hepatic damage induced by malathion acute exposure in rats

Nutrition & Metabolism, 2019
Background Organophosphorus pesticides (OP’s) are heavily constituted in agriculture, gardens, home and veterinary and although it is useful, there are concerns about the environment, safety and health of human and animals. In this study, we investigated
Edina da Luz Abreu, Anne Suély Pinto Savall, Allyson Ardais Boneberg, Bianca Barreto Martins, Vanessa Carratú Gervini, Tuane Bazanella Sampaio, André Ricardo Fajardo, Natália Paroul, Daniel Henrique Roos, Simone Pinton   +9 more
doaj   +1 more source

Neuronal Cell Model and Methods of Use Therefor [PDF]

, 2001
The present invention provides, inter alia, a PC12 cell quiescently infected with a neurotropic virus. Preferred quiescently-infected neural cells are those wherein the neurotropic virus is a neurotropic herpes virus.
Danaher, Robert J., Jacob, Robert J., Miller, Craig S.   +2 more
core   +1 more source