Results 191 to 200 of about 26,803 (327)

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

, 2016
Chunyan Wang, Su Guo, Jia Yu Wang, Xu Guang Yan, Margaret Farrelly, Yuan Yuan Zhang, Fen Liu, Hamed Yari, Ting La, Fu Xi Lei, Lei Jin, Xu Dong Zhang, Chen Chen Jiang   +12 more
openalex   +2 more sources

Reactivation of a latent precore mutant hepatitis B virus related chronic hepatitis during infliximab treatment for severe spondyloarthropathy [PDF]

, 2005
Daniel Wendling, B Auge, D Bettinger, A Lohse, G Le Huede, S Bresson-Hadni, E Toussirot, J-P Miguet, G Herbein, V Di Martino   +9 more
openalex   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

The roles of mutant p53 in reprogramming and inflammation in breast cancers. [PDF]

Cell Death Differ
Kummar S, Fellous M, Levine AJ.
europepmc   +1 more source

Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells. [PDF]

Invest New Drugs, 2023
Tang M, Crown J, Duffy MJ.
europepmc   +1 more source

Biosynthesis of Hematin Compounds in a Hemin Requiring Strain of \u3cem\u3eMicrococcus pyogenes\u3c/em\u3e var. \u3cem\u3eaureus:\u3c/em\u3e I. The Significance of Coenzyme A for the Terminal Synthesis of Catalase [PDF]

, 1957
Jensen, Joerg
core   +1 more source

A Modular DNAzyme for Precise Visualization and Intervention of Alternative Splicing Isoforms in Live Cells

Advanced Science, EarlyView.
A Stringent dUPlex‐activated Error Robust (SUPER) DNAzyme system enables real‐time imaging of alternative mRNA splicing (e.g., Bcl‐xL/Bcl‐xS) in living cells via target‐triggered split‐DNAzyme reassembly and dual‐color fluorescence. It also achieves mRNA‐selective knockdown through DNAzyme‐based gene regulation, serving as a versatile tool for splicing
Mengru Lin, Jiale Sun, Yuqing Mao, Yuhao Tang, Fuan Wang, Zhihong Liu, Jing Wang   +6 more
wiley   +1 more source

UBE2T-Mediated HP1α Ubiquitination Enhances Nucleolar Function and Promotes the Progression of IDH1/TP53-Mutant Glioma. [PDF]

Clin Cancer Res
Zhou F, Sun Y, Chen X, Wu D, Tao Z, Wu L, Chen G, Liu X, Yu T.   +8 more
europepmc   +1 more source

Broad-Spectrum Antidote Discovery by Untangling the Reactivation Mechanism of Nerve-Agent-Inhibited Acetylcholinesterase. [PDF]

Chemistry, 2022
Lindgren C, Forsgren N, Hoster N, Akfur C, Artursson E, Edvinsson L, Svensson R, Worek F, Ekström F, Linusson A.   +9 more
europepmc   +1 more source

Cardiovascular Reactivity [PDF]

Circulation Research, 1954
I H, PAGE, J W, McCUBBIN
openaire   +2 more sources