Results 211 to 220 of about 124,194 (317)

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Structure-guided modification of a lead cholinesterase-targeting oxime to improve peripheral site binding. [PDF]

Arh Hig Rada Toksikol
Maraković N, Probst N, Čadež T, Zandona A.   +3 more
europepmc   +1 more source

Tensile Stimulation in Biorelevant Culture Conditions Enhances MSC and TPSC Tenogenesis on Aligned Electrospun Scaffolds

Advanced NanoBiomed Research, EarlyView.
Biomimetic electrospun scaffold incorporating GDF‐7‐loaded mesoporous silica nanoparticles, combined with mechanical stimulation and physiological oxygen tension, guides tenogenic differentiation of mesenchymal stromal cell and tendon progenitor stem cell. This integrated approach enhances cell proliferation, matrix deposition, and tendon‐specific gene
Vera Citro, Aldo R. Boccaccini, Nicholas R. Forsyth, Tina P. Dale   +3 more
wiley   +1 more source

Nanodiamond mediated delivery of pyridinium oxime antidotes to central nervous system for potential treatment of exposure to nerve agents. [PDF]

Chem Biol Interact
Bondar D, Smirnova O, Nagappa NM, Heinmaa I, Soukup O, Kobrlova T, Opravil J, Hrabinova M, Jun D, Starkov P, Spuul P, Kuča K, Mochalin VN, Karpichev Y.   +13 more
europepmc   +1 more source

Two‐Dimensional Polymers as Modular Metal‐Free Solid‐State Catalysts for Efficient Sono‐Piezo‐Photocatalytic Hydrogen Peroxide Production

Angewandte Chemie International Edition, EarlyView.
This study demonstrates the high piezo‐photocatalytic activity of solid molecular catalysts (SMCs) in the production of hydrogen peroxide from water and oxygen. Through the rational design of molecular motifs (diphenylpyridine or terpyridine) and backbone functionalities (methyl group, aliphatic amine antenna, or aromatic pyrrole unit), as well as ...
Sarah Brettschneider, Keanu V. A. Birkelbach, Marcus Lantzius‐Beninga, Ahmed Mourran, Gurudas Chakraborty, Peter J. C. Hausoul, Andreas Herrmann, Regina Palkovits   +7 more
wiley   +1 more source

Case report: Treatment of severe phorate poisoning. [PDF]

Front Toxicol
Kunlun W, Jun Y, Shiming X, Jie S, Mingqiang G, Yuxia Z, Weichun M.   +6 more
europepmc   +1 more source

Prediction of a new broad-spectrum reactivator capable of reactivating acetylcholinesterase inhibited by nerve agents

, 2005
V. Dohnal, K. Kuča, D. Jun
semanticscholar   +1 more source

Network Theory Analysis of Allosteric Drug-Rescue Mechanisms in the Tumor Suppressor Protein p53 Y220C Mutant. [PDF]

Int J Mol Sci
Cowan BS, Thayer KM.
europepmc   +1 more source

Light‐Responsive Carbon Dots with Photochromism and Excitation‐Dependent Room Temperature Phosphorescence

Advanced Physics Research, EarlyView.
A light‐responsive system with photochromism and excitation‐dependent phosphorescence was constructed by microwave synthesis of nitrogen‐doped carbon dots(N‐CDs), which provides insights into the design and synthesis of CDs with multifunctional optical properties, promoting the application expansion of intelligent responsive materials in the fields of ...
Xiaoqi Fang, Yuan Li, Junjie Cui, Zhenye Xu, Zifei Ge, Chengwei Hu, Khurram Abbas, Hong Bi   +7 more
wiley   +1 more source

Evaluation of a Product Intended for Microbiological Control in Animal Production, and Its Combination With Halquinol

Animal Research and One Health, EarlyView.
Activo Liquid and Halquinol inhibit Salmonella and Escherichia coli in culture media. Activo Liquid exhibits bactericidal action, whereas HA is bacteriostatic, and their combination results in positive or indifferent interactions. This combination effectively inhibits E. coli throughout digestion simulation, thus reducing the required concentrations of
Alberto Gonçalves Evangelista, Lucas dos Santos Janotto, Adriana Paula Possamai, Carolina Cini Perry, Francine Lemes Ribeiro, Rafael Canonenco de Araujo, Fernando Bittencourt Luciano   +6 more
wiley   +1 more source