A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane +33 more
wiley +1 more source
Elevated levels of advanced glycation end-products AGE10 in patients with reactive arthritis caused by Chlamydia trachomatis and Epstein-Barr virus infection. [PDF]
Immunol ResKril I +7 more
europepmc +1 more source
Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis
Arthritis &Rheumatology, EarlyView.Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm +2 more
wiley +1 more source
Reactive Arthritis Unmasked by Tuberculosis: A Rare Case of Poncet's Disease With Disseminated TB in a Malnourished Young Adult. [PDF]
Clin Case RepFarhan K +5 more
europepmc +1 more source
Reactive Arthritis Triggered by Adalimumab and Leflunomide in a Patient with Ankylosing Spondylitis. [PDF]
Clin Cosmet Investig Dermatol, 2022 Liu Y, He J, Jiang J, Wang Y, Liu T.
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Objective The spontaneous K/BxN mouse model of rheumatoid arthritis has been used extensively to study chronic inflammation, contribution of immune cells, and the primordial role of autoreactive antibodies in disease initiation and severity. Only the ubiquitous enzyme glucose‐6‐phosphate isomerase (GPI) is the target of IgG autoantibodies secreted by ...
Thibault Vanhoucke +8 more
wiley +1 more source
When the Infection Clears but Inflammation Persists: A Case of Chlamydia-Associated Reactive Arthritis Requiring Disease-Modifying Antirheumatic Drug (DMARD) Therapy. [PDF]
CureusKhawar Z, Umeozor I, Anis A.
europepmc +1 more source
Arthritis &Rheumatology, EarlyView.Objective Pain is the hallmark symptom of osteoarthritis (OA), and its biologic drivers remain poorly understood. Although the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular Treg cells, is not well understood.
Marie Binvignat +26 more
wiley +1 more source
HLA-B27, Mantoux Test, and Eosinophil Count: Help in the Diagnosis of Reactive Arthritis Due to Tubercular Hypersensitivity. [PDF]
CureusMakkar A, Pai VS, Panda PK.
europepmc +1 more source