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Prohibitins [PDF]

open access: yesCurrent Biology, 2017
Tatsuta and Langer introduce prohibitins, membrane scaffolding proteins found predominantly in mitochondria.
Takashi Tatsuta, Thomas Langer
exaly   +6 more sources

The emerging roles of prohibitins in folliculogenesis [PDF]

open access: yesFrontiers in Bioscience - Elite, 2012
Prohibitins are members of a highly conserved eukaryotic protein family containing the stomatin/prohibitin/flotillin/HflK/C (SPFH) domain (also known as the prohibitin (PHB) domain) found in divergent species from prokaryotes to eukaryotes. Prohibitins are found in unicellular eukaryotes, fungi, plants, animals and humans.
Winston Thompson   +2 more
exaly   +3 more sources

SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability [PDF]

open access: yesBiochimica Et Biophysica Acta - Molecular Cell Research, 2008
International audienceStomatin is a member of a large family of proteins including prohibitins, HflK/C, flotillins, mechanoreceptors and plant defense proteins, that are thought to play a role in protein turnover. Using different proteomic approaches, we
Jean-Claude Martinou, Willy Bienvenut
exaly   +4 more sources

Prohibitins: mitochondrial partners in development and stress response

open access: yesTrends in Plant Science, 2010
Twelve years after their discovery in plants, prohibitins (PHBs) have retained their status as some of the most enigmatic mitochondrial proteins. Although the original hypothesis that PHBs act as negative cell cycle regulators has lost its impetus in ...
James Whelan   +2 more
exaly   +2 more sources

Targeting prohibitins at the cell surface prevents Th17‐mediated autoimmunity

open access: yesEMBO Journal, 2018
peer reviewedT helper (Th)17 cells represent a unique subset of CD4(+) T cells and are vital for clearance of extracellular pathogens including bacteria and fungi. However, Th17 cells are also involved in orchestrating autoimmunity.
Frauke Zipp   +2 more
exaly   +2 more sources

Prohibitins Regulate Membrane Protein Degradation by the m -AAA Protease in Mitochondria

open access: yesMolecular and Cellular Biology, 1999
Prohibitins comprise a protein family in eukaryotic cells with potential roles in senescence and tumor suppression. Phb1p and Phb2p, members of the prohibitin family in Saccharomyces cerevisiae, have been implicated in the regulation of the replicative ...
Thomas Langer
exaly   +1 more source
Some of the next articles are maybe not open access.

Formation of Membrane-bound Ring Complexes by Prohibitins in Mitochondria

Molecular Biology of the Cell, 2005
Thomas Langer, Kirstin Model
exaly  

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