Results 21 to 30 of about 1,545 (164)
Prohibitin and mitochondrial biology [PDF]
Trends in Endocrinology & Metabolism, 2009 Prohibitins are ubiquitous, evolutionarily conserved proteins that are mainly localized in mitochondria. The mitochondrial prohibitin complex comprises two subunits, PHB1 and PHB2. These two proteins assemble into a ring-like macromolecular structure at the inner mitochondrial membrane and are implicated in diverse cellular processes: from ...
Artal-Sanz, Marta +1 more
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Mitochondrial prohibitin complex regulates fungal virulence via ATG24-assisted mitophagy
Communications Biology, 2022 Prohibitins recruit ChATG24 into the mitochondria to modulate mitophagy, thereby affecting the virulence of Colletotrichum higginsianum.
Yaqin Yan +9 more
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Mitophagy: Permitted by Prohibitin [PDF]
Current Biology, 2017 Autophagic responses specific for damaged or superfluous mitochondria are crucial for the maintenance of cellular and organismal homeostasis. Recent data demonstrate that components of the inner mitochondrial membrane that are unmasked upon outer membrane permeabilization facilitate the autophagic destruction of the organelle.
Lorenzo, Galluzzi +2 more
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The role of prohibitin in cell signaling [PDF]
The FEBS Journal, 2010 Prohibitin‐1 (PHB, also known as PHB1), a member of the Band‐7 family of proteins, is highly conserved evolutionarily, widely expressed, and present in different cellular compartments. Genetic studies with different organism models have provided strong evidence for an important biological role of PHB in mitochondrial function, cell proliferation, and ...
Suresh, Mishra +2 more
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Unveiling the potential of prohibitin in cancer [PDF]
Cancer Letters, 2015 Recently, research has shed new light on the role of Prohibitin (PHB) in cancer pathogenesis across an array of cancer types. Important mechanisms for PHB have been unveiled in several cancers, especially with regard to the androgen independent state of prostate cancer (PC) and oestrogen dependent breast cancer.
Koushyar, Sarah +2 more
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The Interferon-Inducible Mouse Apolipoprotein L9 and Prohibitins Cooperate to Restrict Theiler's Virus Replication. [PDF]
PLoS ONE, 2015 Apolipoprotein L9b (Apol9b) is an interferon-stimulated gene (ISG) that has antiviral activity and is weakly expressed in primary mouse neurons as compared to other cell types.
Marguerite Kreit +3 more
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Redox Biology, 2021 Background: Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) are linked to several mitochondrial alterations. Cigarette smoke (CS) alters the structure and function of mitochondria.
Krishna Prahlad Maremanda +2 more
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Prohibitins are required for cancer cell proliferation and adhesion.
PLoS ONE, 2010 Prohibitin 1 (PHB1) is a highly conserved protein that together with its homologue prohibitin 2 (PHB2) mainly localizes to the inner mitochondrial membrane.
Claudia Sievers +3 more
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The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin‐related protein. [PDF]
The EMBO Journal, 1994 The two major classes of antigen receptors on murine B lymphocytes, mIgM and mIgD, are both contained in a complex with two additional molecules, Ig-alpha and Ig-beta, which permit signal transduction. Accordingly, early biochemical events after antigen binding to either receptor are similar; biological effects, however, are different.
M, Terashima +6 more
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Mitochondrial Quality Control Mechanisms and the PHB (Prohibitin) Complex
Cells, 2018 Mitochondrial functions are essential for life, critical for development, maintenance of stem cells, adaptation to physiological changes, responses to stress, and aging.
Blanca Hernando-Rodríguez +1 more
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