Results 41 to 50 of about 1,728 (183)
Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses [PDF]
, 2020 International audienceFlavaglines are cyclopenta[b]benzofurans found in plants of the genus Aglaia, several species of which are used in traditional Chinese medicine.
Nebigil, Canan G +5 more
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Downregulation of lung mitochondrial prohibitin in COPD [PDF]
Respiratory Medicine, 2012 Prohibitins (PHB1 and PHB2) are versatile proteins located at the inner mitochondrial membrane, maintaining normal mitochondrial function and morphology. They interact with the NADH dehydrogenase protein complex, which is essential for oxidoreductase activity within cells. However, their expression in lung epithelium, especially in smokers and patients
Soulitzis, Nikolaos +6 more
openaire +2 more sources
Haematologica, 2017 Fluorizoline is a new synthetic molecule that induces apoptosis by selectively targeting prohibitins. In the study herein, the pro-apoptotic effect of fluorizoline was assessed in 34 primary samples from patients with chronic lymphocytic leukemia ...
Ana M. Cosialls +12 more
doaj +1 more source
The Identification of Prohibitin in the Rat Heart Mitochondria in Heart Failure
Biomedicines, 2021 Mitochondria are considered the main organelles in the cell. They play an important role in both normal and abnormal heart function. There is a supramolecular organization between the complexes of the respiratory chain (supercomplexes (SCs)), which are ...
Yulia Baburina +5 more
doaj +1 more source
Mitochondrial Band-7 family proteins: scaffolds for respiratory chain assembly?
Frontiers in Plant Science, 2014 The band-7 protein family comprises a diverse set of membrane-bound proteins characterised by the presence of a conserved domain. The exact function of this band-7 domain remains elusive, but examples from animal and bacterial stomatin-type proteins ...
Bernadette eGehl, Lee James Sweetlove
doaj +1 more source
The IgM antigen receptor of B lymphocytes is associated with prohibitin and a prohibitin-related protein. [PDF]
The EMBO Journal, 1994 The two major classes of antigen receptors on murine B lymphocytes, mIgM and mIgD, are both contained in a complex with two additional molecules, Ig-alpha and Ig-beta, which permit signal transduction. Accordingly, early biochemical events after antigen binding to either receptor are similar; biological effects, however, are different.
M, Terashima +6 more
openaire +2 more sources
Mitochondrial dysfunction and adipogenic reduction by prohibitin silencing in 3T3-L1 cells. [PDF]
PLoS ONE, 2012 Increase in mitochondrial biogenesis has been shown to accompany brown and white adipose cell differentiation. Prohibitins (PHBs), comprised of two evolutionarily conserved proteins, prohibitin-1 (PHB1) and prohibitin-2 (PHB2), are present in a high ...
Dong Liu +9 more
doaj +1 more source
Parasites & Vectors, 2018 Background Leishmaniasis, a disease caused by parasites of the genus Leishmania, infects roughly 12 million people worldwide, with about two million new cases per year. Prohibitins (PHBs) are highly conserved proteins belonging to the stomatin-prohibitin
Teresa Cruz-Bustos +4 more
doaj +1 more source
Biological and Cellular Functions of the Microdomain-Associated FWL/CNR Protein Family in Plants
Plants, 2020 Membrane microdomains/nanodomains are sub-compartments of the plasma membrane enriched in sphingolipids and characterized by their unique protein composition.
Sandra Thibivilliers +2 more
doaj +1 more source
PLoS Genetics, 2012 Fusion and fission of mitochondria maintain the functional integrity of mitochondria and protect against neurodegeneration, but how mitochondrial dysfunctions trigger neuronal loss remains ill-defined.
Carsten Merkwirth +7 more
doaj +1 more source