Results 61 to 70 of about 1,827 (179)
Parasites & Vectors, 2018 Background Leishmaniasis, a disease caused by parasites of the genus Leishmania, infects roughly 12 million people worldwide, with about two million new cases per year. Prohibitins (PHBs) are highly conserved proteins belonging to the stomatin-prohibitin
Teresa Cruz-Bustos +4 more
doaj +1 more source
Expression of prohibitins on the surface of activated T cells. [PDF]
, 2012 Prohibitins (prohibitin-1 and -2) comprise a family of highly conserved proteins that are mainly localized to mitochondria. Recent studies showed that prohibitins are up-regulated upon T cell activation and play an essential role in maintaining ...
19346 +13 more
core +1 more source
Biological and Cellular Functions of the Microdomain-Associated FWL/CNR Protein Family in Plants
Plants, 2020 Membrane microdomains/nanodomains are sub-compartments of the plasma membrane enriched in sphingolipids and characterized by their unique protein composition.
Sandra Thibivilliers +2 more
doaj +1 more source
Prohibitin as an oxidative stress biomarker in the eye [PDF]
International Journal of Biological Macromolecules, 2010 Identification of biomarker proteins in the retina and retinal pigment epithelium (RPE) under oxidative stress may imply new insights into signaling mechanisms of retinal degeneration at the molecular level. Proteomic data from an in vivo mice model in constant light and an in vitro oxidative stress model are compared to controls under normal ...
Hyunju, Lee +10 more
openaire +2 more sources
PLoS Genetics, 2012 Fusion and fission of mitochondria maintain the functional integrity of mitochondria and protect against neurodegeneration, but how mitochondrial dysfunctions trigger neuronal loss remains ill-defined.
Carsten Merkwirth +7 more
doaj +1 more source
Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity. [PDF]
PLoS ONE, 2015 Magnesium (Mg2+) is essential for enzymatic activity, brain function and muscle contraction. Blood Mg2+ concentrations are tightly regulated between 0.7 and 1.1 mM by Mg2+ (re)absorption in kidney and intestine.
Maxime G Blanchard +8 more
doaj +1 more source
Structure-function analysis of human stomatin: A mutation study. [PDF]
PLoS ONE, 2017 Stomatin is an ancient, widely expressed, oligomeric, monotopic membrane protein that is associated with cholesterol-rich membranes/lipid rafts. It is part of the SPFH superfamily including stomatin-like proteins, prohibitins, flotillin/reggie proteins ...
Stefanie Rungaldier +5 more
doaj +1 more source
Advanced Science, EarlyView.Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo +11 more
wiley +1 more source
Prohibitin, an antiproliferative protein, is localized to mitochondria
FEBS Letters, 1995 Prohibitin is a ubiquitously expressed protein with antiproliferative properties. When rat prohibitin tagged with a carboxy‐terminal c‐Myc epitope was expressed in baby hamster kidney cells the protein was targeted to mitochondria. In immunofluorescence microscopy prohibitin colocalized with a mitochondrial marker E3. Immunoelectron microscopy revealed
Ikonen, E +3 more
openaire +5 more sources
Flavaglines as natural products targeting eIF4A and prohibitins: From traditional Chinese medicine to antiviral activity against coronaviruses [PDF]
, 2020 International audienceFlavaglines are cyclopenta[b]benzofurans found in plants of the genus Aglaia, several species of which are used in traditional Chinese medicine.
Nebigil, Canan G +5 more
core +2 more sources